HCPCS Level II A4606: Oxygen Probe for Oximeter, Replacement

HCPCS Level II code A4606 identifies a replacement oxygen probe used with oximeter devices to measure peripheral oxygen saturation. The code covers a common durable medical equipment (DME) component needed across clinical, home care and outpatient settings. Nationally, replacement oximeter probes affect device maintenance, DME inventory management, and procedural accuracy for pulse oximetry monitoring.

Key payers discussed include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare and Medicare. Readers will find an overview of payer coverage patterns, billing considerations for replacement DME components, and operational benchmarks relevant to reimbursement and supply management. The review highlights typical sites of service where A4606 is billed, coding context for replacement parts, and the implications for claims processing and documentation requirements.

This analysis provides practical context for billing staff, DME suppliers, and compliance teams: what A4606 represents, how payers commonly treat replacement oximeter probes, and what operational metrics and policy updates to monitor. Data not available in the input is noted where applicable.

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Billing Code Overview

HCPCS Level II code A4606 represents an oxygen probe for use with an oximeter device, replacement. This item is a replaceable sensor component designed to measure peripheral oxygen saturation when connected to a compatible oximeter.

Service Type: Durable medical equipment component, replacement part
Typical Site of Service: Durable medical equipment settings, outpatient clinics, home health care environments, and other sites where oximetry devices are used

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HCPCS Level II A4606: Oxygen Probe for Oximeter, Replacement

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Billing Code Overview

Service Type: Durable medical equipment component, replacement part
Typical Site of Service: Durable medical equipment settings, outpatient clinics, home health care environments, and other sites where oximetry devices are used

Clinical & Coding Specifications

Clinical Context

A patient with a prescription for home pulse oximetry presents to a durable medical equipment (DME) supplier to obtain replacement components for their pulse oximeter. The supplier confirms the existing oximeter is functional but the reusable oxygen probe (sensor) has worn tubing and intermittent signal loss. The DME clinician documents patient identity, device make/model, reason for replacement (wear/contamination/damage), and that a replacement oxygen probe is medically necessary to ensure accurate SpO2 monitoring at home. The supplier dispenses the replacement oxygen probe A4606, records the device serial number, and provides patient education on proper probe attachment, cleaning, and storage. The typical workflow includes verification of the original device prescription, confirmation of medical necessity (e.g., chronic hypoxemia, recent hospital discharge requiring home monitoring), capturing supplier invoice and manufacturer part number, and submission of the HCPCS Level II code A4606 to the payer with appropriate modifier(s) if applicable. Typical site of service is a durable medical equipment supplier or the patient’s home when delivered by the supplier.

Related Diagnoses

ICD-10 Code	Description	Clinical Relevance
`J44.9`	Chronic obstructive pulmonary disease, unspecified	Patients with COPD commonly require home pulse oximetry to monitor oxygen saturation and guide supplemental oxygen use.
`J96.00`	Acute respiratory failure, unspecified whether with hypoxia or hypercapnia	Pulse oximetry sensors are essential for monitoring oxygenation in patients recovering from respiratory failure who require home monitoring.
`R09.02`	Hypoxemia	Direct indication for oxygen saturation monitoring and replacement of worn or malfunctioning oximeter probes.
`I50.9`	Heart failure, unspecified	Heart failure patients may have hypoxemia or require close oxygen monitoring, making replacement probes clinically relevant.
`Z46.6`	Encounter for fitting and adjustment of respiratory device	Administrative code used when equipment fitting, replacement, or adjustment of monitoring devices occurs.

Related CPT Codes

CPT Code	Description	Relationship to This Procedure
`94640`	Pressurized or nonpressurized inhalation treatment for acute airway obstruction or for sputum induction for diagnostic purposes (e.g., nebulizer therapy)	May be performed in conjunction with oxygen therapy management; respiratory therapists providing device education may also document therapeutic treatments in the same visit.
`94760`	Noninvasive ear or pulse oximetry for oxygen saturation (single determination)	Diagnostic code for a point-in-time SpO2 measurement often used before or after replacement of an oxygen probe to verify device function.
`99070`	Supplies and materials (except spectacles), provided by the physician over and above those usually included with the office visit	May be used by suppliers or clinicians to bill for small replacement items or supplies when payer allows; check payer policy for use with `A4606`.
`99000`	Handling and/or conveyance of specimen for transfer from the patient to a third-party laboratory (historical)	Rarely applicable; included for completeness when facility billing routines require a supply-handling code in the encounter.
`98960`	Education and training for patient self-management for a single chronic condition; individual, face-to-face, 30 minutes	Patient education on probe use and SpO2 monitoring may be billed using patient education codes if payer rules permit separate billing.

Related Modifiers

6 rows

Modifier
52
53
55
62
80
82

Related Provider Taxonomies

8 rows

Taxonomy Code
332B00000X
363LA2200X
207RR0500X
207T00000X
261QP3300X
2278H0200X
364SR0400X
207UN0902X

Related Codes

HCPCS-A4206-STERILE-SYRINGE-1CC-NEEDLE

HCPCS Level II A4206: Sterile Syringe with Needle, 1 cc or Less

HCPCS-A4207-STERILE-2CC-SYRINGE-WITH-NEEDLE

HCPCS A4207: Syringe with Needle, Sterile 2 cc, Each

HCPCS-A4208-STERILE-3CC-SYRINGE-WITH-NEEDLE

HCPCS Level II A4208: Syringe with Needle, Sterile 3 cc, Each

HCPCS-A4209-STERILE-SYRINGE-WITH-NEEDLE-5CC-OR-GREATER

HCPCS A4209: Syringe with Needle, Sterile 5 cc or Greater

HCPCS-A4210-NEEDLE-FREE-INJECTION-DEVICE

HCPCS A4210: Needle-Free Injection Device, Single

HCPCS-A4211-SUPPLIES-SELF-ADMINISTERED-INJECTIONS

HCPCS A4211: Supplies for Self-Administered Injections

HCPCS-A4212-NON-CORING-NEEDLE-STYLET-CATHETER-ACCESS-SUPPLY

HCPCS Level II A4212: Non-coring Needle or Stylet with or without Catheter

HCPCS-A4213-STERILE-SYRINGE-20CC-OR-GREATER

HCPCS Level II A4213: Sterile Syringe, 20 cc or Greater

HCPCS-A4215-STERILE-NEEDLE-SINGLE-EACH

HCPCS Level II A4215: Sterile Needle, Single Use, Each

HCPCS-A4216-STERILE-DILUENT-FLUSH-10ML

HCPCS A4216: Sterile Diluent/Flush, 10 ml

Showing 1–10 of 633

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

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Clinical & Coding Specifications

Clinical Context

Related Diagnoses

ICD-10 Code	Description	Clinical Relevance
`J44.9`	Chronic obstructive pulmonary disease, unspecified	Patients with COPD commonly require home pulse oximetry to monitor oxygen saturation and guide supplemental oxygen use.
`J96.00`	Acute respiratory failure, unspecified whether with hypoxia or hypercapnia	Pulse oximetry sensors are essential for monitoring oxygenation in patients recovering from respiratory failure who require home monitoring.
`R09.02`	Hypoxemia	Direct indication for oxygen saturation monitoring and replacement of worn or malfunctioning oximeter probes.
`I50.9`	Heart failure, unspecified	Heart failure patients may have hypoxemia or require close oxygen monitoring, making replacement probes clinically relevant.
`Z46.6`	Encounter for fitting and adjustment of respiratory device	Administrative code used when equipment fitting, replacement, or adjustment of monitoring devices occurs.

Related CPT Codes

CPT Code	Description	Relationship to This Procedure
`94640`	Pressurized or nonpressurized inhalation treatment for acute airway obstruction or for sputum induction for diagnostic purposes (e.g., nebulizer therapy)	May be performed in conjunction with oxygen therapy management; respiratory therapists providing device education may also document therapeutic treatments in the same visit.
`94760`	Noninvasive ear or pulse oximetry for oxygen saturation (single determination)	Diagnostic code for a point-in-time SpO2 measurement often used before or after replacement of an oxygen probe to verify device function.
`99070`	Supplies and materials (except spectacles), provided by the physician over and above those usually included with the office visit	May be used by suppliers or clinicians to bill for small replacement items or supplies when payer allows; check payer policy for use with `A4606`.
`99000`	Handling and/or conveyance of specimen for transfer from the patient to a third-party laboratory (historical)	Rarely applicable; included for completeness when facility billing routines require a supply-handling code in the encounter.
`98960`	Education and training for patient self-management for a single chronic condition; individual, face-to-face, 30 minutes	Patient education on probe use and SpO2 monitoring may be billed using patient education codes if payer rules permit separate billing.

Related Modifiers

6 rows

Modifier
52
53
55
62
80
82

Related Provider Taxonomies

8 rows

Taxonomy Code
332B00000X
363LA2200X
207RR0500X
207T00000X
261QP3300X
2278H0200X
364SR0400X
207UN0902X

Related Codes

HCPCS-A4206-STERILE-SYRINGE-1CC-NEEDLE

HCPCS Level II A4206: Sterile Syringe with Needle, 1 cc or Less

HCPCS-A4207-STERILE-2CC-SYRINGE-WITH-NEEDLE

HCPCS A4207: Syringe with Needle, Sterile 2 cc, Each

HCPCS-A4208-STERILE-3CC-SYRINGE-WITH-NEEDLE

HCPCS Level II A4208: Syringe with Needle, Sterile 3 cc, Each

HCPCS-A4209-STERILE-SYRINGE-WITH-NEEDLE-5CC-OR-GREATER

HCPCS A4209: Syringe with Needle, Sterile 5 cc or Greater

HCPCS-A4210-NEEDLE-FREE-INJECTION-DEVICE

HCPCS A4210: Needle-Free Injection Device, Single

HCPCS-A4211-SUPPLIES-SELF-ADMINISTERED-INJECTIONS

HCPCS A4211: Supplies for Self-Administered Injections

HCPCS-A4212-NON-CORING-NEEDLE-STYLET-CATHETER-ACCESS-SUPPLY

HCPCS Level II A4212: Non-coring Needle or Stylet with or without Catheter

HCPCS-A4213-STERILE-SYRINGE-20CC-OR-GREATER

HCPCS Level II A4213: Sterile Syringe, 20 cc or Greater

HCPCS-A4215-STERILE-NEEDLE-SINGLE-EACH

HCPCS Level II A4215: Sterile Needle, Single Use, Each

HCPCS-A4216-STERILE-DILUENT-FLUSH-10ML

HCPCS A4216: Sterile Diluent/Flush, 10 ml

Showing 1–10 of 633

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.