HCPCS A2039: Innovamatrix FD, Per Square Centimeter (Add-on)

Medicare pays $133 on average nationally for this procedure.

HCPCS Level II code A2039 describes billing for Innovamatrix FD charged per square centimeter as an add-on product used in surgical wound or skin repair procedures, typically supplied in outpatient surgical centers or hospital operating rooms and documented alongside the primary procedure for tissue regeneration or dermal matrix placement.

For related coverage guidance, see recent payer policy updates: Gynecomastia Surgery, Panniculectomy (Abdominal skin/fat surgery), Cosmetic and Reconstructive Procedures (for Ohio Only).

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HCPCS A2039: Innovamatrix FD, Per Square Centimeter (Add-on)

Medicare pays $133 on average nationally for this procedure.

For related coverage guidance, see recent payer policy updates: Gynecomastia Surgery, Panniculectomy (Abdominal skin/fat surgery), Cosmetic and Reconstructive Procedures (for Ohio Only).

Customize your policy alerts

Sign up for hcpcs A2039 policy alerts

Get alerted when payer policies referencing A2039 are released or updated.

Monitor payer policy activity

Receive email alerts as soon as relevant payer policies are published or updated.

Clinical & Coding Specifications

Clinical Context

A typical patient is an adult with a full-thickness or partial-thickness skin loss following trauma, surgical excision of a chronic wound or necrotic tissue, or a non-healing ulcer (e.g., diabetic foot ulcer, venous stasis ulcer). The clinician prepares the wound by debridement and hemostasis in an outpatient procedure room or ambulatory surgical center, then applies a biologic matrix dressing — billed using A2039 per square centimeter as an add-on material charge. The workflow includes wound assessment, sterile preparation, measurement of defect size to determine square centimeters of product used, application of the Innovamatrix FD product to the wound bed, securement with a secondary dressing, and patient/caregiver instructions for wound care and follow-up. Typical sites of service are outpatient wound clinics, physician offices with procedure capability, hospital outpatient departments, and ambulatory surgical centers. Common clinical teams include wound care specialists, general surgeons, plastic surgeons, podiatrists, and advanced practice providers overseeing dressing application and follow-up care.

Related CPT Codes

CPT Code	Description	Relationship to This Procedure
`11042`	Debridement, subcutaneous tissue (first 20 sq cm)	Often performed immediately prior to placement of a biologic matrix to prepare a clean wound bed.
`97602`	Removal of devitalized tissue from wound(s), selective debridement; without anesthesia (e.g., high-pressure waterjet)	May be used for non-surgical debridement prior to matrix application in clinic settings.
`15271`	Application of skin substitute graft to trunk, arms, legs; first 100 sq cm or less, wound(s) with exposed muscle, tendon, cartilage or bone	Used when a skin substitute graft is applied; relates to use of biologic matrices for larger or deeper wounds needing grafting.
`11044`	Debridement, muscle and/or fascia (first 20 sq cm)	Used when deeper debridement is required before application of a biologic matrix product.
`97605`	Negative pressure wound therapy (e.g., vacuum-assisted closure), initial; total wound(s) surface area up to 50 sq cm	May be used after matrix application to secure the product and promote adherence and healing.

Related Modifiers

5 rows

Modifier	Description	When to Use
22	Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…	- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
52	Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…	- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
53	Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…	- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
26	Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…	- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
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Related Provider Taxonomies

8 rows

Taxonomy Code	Specialty	Notes
207P00000X	Emergency Medicine Physician	An emergency physician focuses on the immediate decision making and action necessary to prevent death or any further disability both in the pre-hospit…
207Q00000X	Family Medicine Physician	Family Medicine is the medical specialty which is concerned with the total health care of the individual and the family. It is the specialty in breadt…
207X00000X	Orthopaedic Surgery Physician	An orthopaedic surgeon is trained in the preservation, investigation and restoration of the form and function of the extremities, spine and associated…
363A00000X	Physician Assistant	A physician assistant is a person who has successfully completed an accredited education program for physician assistant, is licensed by the state and…
363L00000X	Nurse Practitioner	(1) A registered nurse provider with a graduate degree in nursing prepared for advanced practice involving independent and interdependent decision mak…
207SG0202X	Clinical Biochemical Genetics Physician	A clinical biochemical geneticist demonstrates competence in performing and interpreting biochemical analyses relevant to the diagnosis and management…
226000000X	Recreational Therapist Assistant	Recreational Therapist Assistants work in support of or assistant to Recreational Therapists treating patients with disabilities, injuries, and illnes…
213EP0504X	Public Medicine Podiatrist	Podiatric Medicine & Surgery Service Providers · Podiatrist

Related ICD-10-CM Codes

21 rows

ICD-10-CM Code	Description
E10.621	Type 1 diabetes mellitus with foot ulcer
E11.621	Type 2 diabetes mellitus with foot ulcer
E11.622	Type 2 diabetes mellitus with other skin ulcer
I83.10	Varicose veins of unspecified lower extremity with inflammation
I83.813	Varicose veins of bilateral lower extremities with pain
I83.90	Asymptomatic varicose veins of unspecified lower extremity
L03.115	Cellulitis of right lower limb
L03.116	Cellulitis of left lower limb
L89.153	Pressure ulcer of sacral region, stage 3
L89.154	Pressure ulcer of sacral region, stage 4

Showing 1–10 of 21

Related Payer Policy Updates

Specialty: Plastic/Reconstructive Surgery1 / 3

10 rows

Policy	Payer	Effective Date
Gynecomastia Surgery	Cigna	2026-08-15
Panniculectomy (Abdominal skin/fat surgery)	moda_health_plan_inc	2026-08-13
Cosmetic and Reconstructive Procedures (for Ohio Only)	UnitedHealthcare	2026-08-01
Breast Reduction Surgery (for Idaho Only)	UnitedHealthcare	2026-08-01
Cosmetic and Reconstructive Procedures (for Tennessee Only)	UnitedHealthcare	2026-08-01
Cosmetic and Reconstructive Procedures (for Kentucky Only)	UnitedHealthcare	2026-08-01
Panniculectomy Surgery (for Kansas Only)	UnitedHealthcare	2026-08-01
Panniculectomy Surgery (for Tennessee Only)	UnitedHealthcare	2026-08-01
Liposuction for Lipedema	Ambetter Georgia	2026-08-01
Panniculectomy Surgery (for Nebraska Only)	UnitedHealthcare	2026-08-01

Related Codes

HCPCS-A2001-INNOVAMATRIX-PER-SQ-CM

HCPCS Level II A2001: Innovamatrix ac, per square centimeter (add-on)

HCPCS-A2002-MIRRAGEN-ADVANCED-WOUND-MATRIX-PER-CM2

HCPCS Level II A2002: Mirragen Advanced Wound Matrix, per sq cm

HCPCS-A2004-XCELLISTEM-1MG-SPECIALTY-BIOLOGIC-SUPPLY

HCPCS A2004: Xcellistem, 1 mg

HCPCS-A2005-MICROLYTE-MATRIX-WOUND-BIOMATERIAL-PER-CM2

HCPCS Level II A2005: Microlyte Matrix, Per Square Centimeter

HCPCS-A2006-NOVOSORB-DERMAL-MATRIX-PER-CM

HCPCS A2006: Novosorb Synpath Dermal Matrix, per cm2

HCPCS-A2007-RESTRATA-PER-SQ-CM-TOPICAL-WOUND-MATERIAL

HCPCS Level II A2007: Restrata, per Square Centimeter (Add-on)

HCPCS-A2008-THERAGENESIS-PER-SQUARE-CENTIMETER-ADD-ON

HCPCS Level II A2008: Theragenesis, Per Square Centimeter

HCPCS-A2009-SYMPHONY-PER-SQUARE-CENTIMETER-ADD-ON

HCPCS Level II A2009: Symphony, per Square Centimeter (Add-on)

HCPCS-A2010-APIS-PER-SQUARE-CENTIMETER-TOPICAL-BIOLOGIC-ADD-ON

HCPCS Level II A2010: Apis Topical Product Per Square Centimeter

HCPCS-A2011-SUPRA-SDRM-PER-SQ-CM-ADD-ON

HCPCS Level II A2011: Suprasdrm per Square Centimeter (Add-on)

Showing 1–10 of 43

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

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Trek Health ingests and normalizes Transparency in Coverage data and payer policy updates to give provider organizations a clear view of how commercial reimbursement behaves across markets, payers, and services. Our platform transforms raw payer disclosures into structured intelligence that supports contract evaluation, payer negotiations, and service line strategy. By combining market benchmarks with ongoing policy visibility, Trek helps teams identify variability, risk, and opportunity in commercial reimbursement. The result is faster insight, stronger negotiating positions, and more informed financial decisions.

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Clinical & Coding Specifications

Clinical Context

Related CPT Codes

CPT Code	Description	Relationship to This Procedure
`11042`	Debridement, subcutaneous tissue (first 20 sq cm)	Often performed immediately prior to placement of a biologic matrix to prepare a clean wound bed.
`97602`	Removal of devitalized tissue from wound(s), selective debridement; without anesthesia (e.g., high-pressure waterjet)	May be used for non-surgical debridement prior to matrix application in clinic settings.
`15271`	Application of skin substitute graft to trunk, arms, legs; first 100 sq cm or less, wound(s) with exposed muscle, tendon, cartilage or bone	Used when a skin substitute graft is applied; relates to use of biologic matrices for larger or deeper wounds needing grafting.
`11044`	Debridement, muscle and/or fascia (first 20 sq cm)	Used when deeper debridement is required before application of a biologic matrix product.
`97605`	Negative pressure wound therapy (e.g., vacuum-assisted closure), initial; total wound(s) surface area up to 50 sq cm	May be used after matrix application to secure the product and promote adherence and healing.

Related Modifiers

5 rows

Modifier	Description	When to Use
22	Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…	- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
52	Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…	- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
53	Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…	- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
26	Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…	- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
[object Object]

Related Provider Taxonomies

8 rows

Taxonomy Code	Specialty	Notes
207P00000X	Emergency Medicine Physician	An emergency physician focuses on the immediate decision making and action necessary to prevent death or any further disability both in the pre-hospit…
207Q00000X	Family Medicine Physician	Family Medicine is the medical specialty which is concerned with the total health care of the individual and the family. It is the specialty in breadt…
207X00000X	Orthopaedic Surgery Physician	An orthopaedic surgeon is trained in the preservation, investigation and restoration of the form and function of the extremities, spine and associated…
363A00000X	Physician Assistant	A physician assistant is a person who has successfully completed an accredited education program for physician assistant, is licensed by the state and…
363L00000X	Nurse Practitioner	(1) A registered nurse provider with a graduate degree in nursing prepared for advanced practice involving independent and interdependent decision mak…
207SG0202X	Clinical Biochemical Genetics Physician	A clinical biochemical geneticist demonstrates competence in performing and interpreting biochemical analyses relevant to the diagnosis and management…
226000000X	Recreational Therapist Assistant	Recreational Therapist Assistants work in support of or assistant to Recreational Therapists treating patients with disabilities, injuries, and illnes…
213EP0504X	Public Medicine Podiatrist	Podiatric Medicine & Surgery Service Providers · Podiatrist

Related ICD-10-CM Codes

21 rows

ICD-10-CM Code	Description
E10.621	Type 1 diabetes mellitus with foot ulcer
E11.621	Type 2 diabetes mellitus with foot ulcer
E11.622	Type 2 diabetes mellitus with other skin ulcer
I83.10	Varicose veins of unspecified lower extremity with inflammation
I83.813	Varicose veins of bilateral lower extremities with pain
I83.90	Asymptomatic varicose veins of unspecified lower extremity
L03.115	Cellulitis of right lower limb
L03.116	Cellulitis of left lower limb
L89.153	Pressure ulcer of sacral region, stage 3
L89.154	Pressure ulcer of sacral region, stage 4

Showing 1–10 of 21

Related Payer Policy Updates

Specialty: Plastic/Reconstructive Surgery1 / 3

10 rows

Policy	Payer	Effective Date
Gynecomastia Surgery	Cigna	2026-08-15
Panniculectomy (Abdominal skin/fat surgery)	moda_health_plan_inc	2026-08-13
Cosmetic and Reconstructive Procedures (for Ohio Only)	UnitedHealthcare	2026-08-01
Breast Reduction Surgery (for Idaho Only)	UnitedHealthcare	2026-08-01
Cosmetic and Reconstructive Procedures (for Tennessee Only)	UnitedHealthcare	2026-08-01
Cosmetic and Reconstructive Procedures (for Kentucky Only)	UnitedHealthcare	2026-08-01
Panniculectomy Surgery (for Kansas Only)	UnitedHealthcare	2026-08-01
Panniculectomy Surgery (for Tennessee Only)	UnitedHealthcare	2026-08-01
Liposuction for Lipedema	Ambetter Georgia	2026-08-01
Panniculectomy Surgery (for Nebraska Only)	UnitedHealthcare	2026-08-01

Related Codes

HCPCS-A2001-INNOVAMATRIX-PER-SQ-CM

HCPCS Level II A2001: Innovamatrix ac, per square centimeter (add-on)

HCPCS-A2002-MIRRAGEN-ADVANCED-WOUND-MATRIX-PER-CM2

HCPCS Level II A2002: Mirragen Advanced Wound Matrix, per sq cm

HCPCS-A2004-XCELLISTEM-1MG-SPECIALTY-BIOLOGIC-SUPPLY

HCPCS A2004: Xcellistem, 1 mg

HCPCS-A2005-MICROLYTE-MATRIX-WOUND-BIOMATERIAL-PER-CM2

HCPCS Level II A2005: Microlyte Matrix, Per Square Centimeter

HCPCS-A2006-NOVOSORB-DERMAL-MATRIX-PER-CM

HCPCS A2006: Novosorb Synpath Dermal Matrix, per cm2

HCPCS-A2007-RESTRATA-PER-SQ-CM-TOPICAL-WOUND-MATERIAL

HCPCS Level II A2007: Restrata, per Square Centimeter (Add-on)

HCPCS-A2008-THERAGENESIS-PER-SQUARE-CENTIMETER-ADD-ON

HCPCS Level II A2008: Theragenesis, Per Square Centimeter

HCPCS-A2009-SYMPHONY-PER-SQUARE-CENTIMETER-ADD-ON

HCPCS Level II A2009: Symphony, per Square Centimeter (Add-on)

HCPCS-A2010-APIS-PER-SQUARE-CENTIMETER-TOPICAL-BIOLOGIC-ADD-ON

HCPCS Level II A2010: Apis Topical Product Per Square Centimeter

HCPCS-A2011-SUPRA-SDRM-PER-SQ-CM-ADD-ON

HCPCS Level II A2011: Suprasdrm per Square Centimeter (Add-on)

Showing 1–10 of 43

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

HCPCS A2039: Innovamatrix FD, Per Square Centimeter (Add-on)

Sign up for hcpcs A2039 policy alerts

HCPCS A2039: Innovamatrix FD, Per Square Centimeter (Add-on)

Sign up for hcpcs A2039 policy alerts

Clinical & Coding Specifications

Clinical Context

Related CPT Codes

Related Modifiers

Related Provider Taxonomies

Related ICD-10-CM Codes

Related Payer Policy Updates

Related Codes

What does HCPCS code A2039 represent and how is it billed?

Where and by which providers is Innovamatrix FD commonly applied?

Which modifiers apply to A2039 and when should they be used?

What CPT codes are commonly associated with procedures performed alongside A2039?

Which payers are included in the analysis and how can payer policies affect claims for A2039?

References

Clinical & Coding Specifications

Clinical Context

Related CPT Codes

Related Modifiers

Related Provider Taxonomies

Related ICD-10-CM Codes

Related Payer Policy Updates

Related Codes

What does HCPCS code A2039 represent and how is it billed?

Where and by which providers is Innovamatrix FD commonly applied?

Which modifiers apply to A2039 and when should they be used?

What CPT codes are commonly associated with procedures performed alongside A2039?

Which payers are included in the analysis and how can payer policies affect claims for A2039?

References