CPT code 96420 denotes intra-arterial push administration of a chemotherapy agent, a targeted delivery technique used to direct cytotoxic therapy into the arterial supply of a tumor or organ. Nationally, the code is important for billing oncology and interventional radiology services where intra-arterial chemotherapy is employed for locoregional treatment strategies.

Key payers in the national landscape include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find an overview of clinical context for intra-arterial push administration, payment and coding considerations relevant to major payers, and benchmarking where available. The publication summarizes common modifiers associated with procedural billing, typical sites of service, and operational implications for facilities that perform intra-arterial chemotherapy.

This summary provides clinicians, billing professionals, and policy analysts with the clinical definition of the service, a payer-focused view of coverage and coding practices, and guidance on what to expect in terms of documentation and claim reporting. Data not available in the input are explicitly noted where applicable.