CPT code 91010 covers diagnostic esophageal manometry in which a provider uses a manometer to measure esophageal muscle pressure and motility, interprets the findings, and produces a formal report. This test is commonly used in the evaluation of gastroesophageal reflux disease (GERD) and other esophageal motility disorders; accurate documentation of interpretation and reporting is central to clinical decision-making and appropriate billing. Nationally, esophageal manometry is an established diagnostic tool in gastroenterology and factors such as site-of-service, documentation of interpretation, and payer-specific coverage rules influence reimbursement and utilization.

Key payers discussed include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find a concise explanation of the clinical context for CPT code 91010, typical sites of service, and the types of documentation that support reporting. The publication also summarizes payer coverage considerations, common modifiers associated with procedural and professional components, and related billing topics relevant to coding integrity. This resource is intended for billing professionals, gastroenterology clinicians, and policy analysts seeking a national overview of how CPT code 91010 is used and reported.