Summary & Overview
CPT 90748: Hepatitis B and Haemophilus influenzae b Combination Vaccine, IM
CPT code 90748 denotes an intramuscular combination vaccine for hepatitis B and Haemophilus influenzae type b (Hib). This immunization is an important preventive intervention that reduces incidence of hepatitis B infection and invasive Hib disease, particularly in pediatric and at-risk adult populations. Nationally, combination vaccines like this support streamlined immunization schedules and can improve adherence by reducing the number of injections required.
Key payers referenced in the analysis include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Coverage policies and coding expectations across these payers influence billing practices, claim adjudication, and vaccination program implementation in ambulatory settings.
Readers will find a concise overview of clinical purpose and service setting, common modifiers and billing considerations, payer coverage listing, and where to find related coding guidance. The publication also outlines practical coding context for vaccine administration in outpatient and community vaccination settings, and notes where input data is unavailable. This summary is intended for coding professionals, clinic administrators, and policy analysts seeking a national-level reference for CPT code 90748.
Billing Code Overview
CPT code 90748 represents a combination vaccine administered intramuscularly that protects against hepatitis B and Haemophilus influenzae type b (Hib). The vaccine is formulated to provide immunization against the liver infection caused by hepatitis B virus and invasive disease caused by Haemophilus influenzae type b.
Service Type: Combination vaccine administration, intramuscular injection.
Typical Site of Service: Outpatient clinics, primary care offices, pediatric offices, community vaccination centers, and other ambulatory care settings.
Data not available in the input.
Clinical & Coding Specifications
Clinical Context
A 6-month-old infant presents to a pediatric clinic for routine immunizations. The child is due for primary series vaccinations and receives the combination hepatitis B and Haemophilus influenzae type b (Hib) vaccine administered intramuscularly in the anterolateral thigh. The clinical workflow includes verification of immunization history, screening for contraindications (severe allergic reaction to a prior dose or vaccine component), informed consent from the parent, preparation of the appropriate combination vaccine dose, administration using aseptic technique, documentation of lot number, manufacturer, site and route of administration, and scheduling of follow-up vaccine appointments. Observation for 15 minutes post-vaccination for potential immediate adverse reactions is performed. Billing staff assign 90748 for the combination HepB-Hib intramuscular vaccination and append applicable modifiers for circumstances such as professional component, reduced services, or patient condition as needed.
Coding Specifications
| Modifier | Description | When to Use |
|---|---|---|
00 | No modifier (not a standard CMS modifier but listed) | Use when no specific modifier is required for the vaccine administration claim |
22 |