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CPT 87153: Nucleic Acid Sequencing for Organism Typing
CPT code 87153 designates nucleic acid sequencing analysis performed on a previously isolated and identified organism to provide more specific taxonomic categorization, such as typing to strain or subtype. Clinically, this service supports precise organism identification for epidemiology, outbreak investigation, antimicrobial stewardship, and research; operationally, it represents a specialized laboratory molecular diagnostic procedure carried out by trained laboratory personnel.
Key payers in the national analysis include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. The publication outlines how CPT code 87153 is used in laboratory billing across these major payers and provides context on clinical indications and typical sites of service.
Readers will find benchmarks for service utilization and payer coverage patterns where available, summaries of clinical and operational context for sequencing-based organism typing, and notes on billing considerations tied to the code description. Data not provided in the input are noted as unavailable. The content is intended for a national audience of laboratory managers, coding professionals, and policy analysts seeking a concise reference to the clinical role and billing identity of CPT code 87153.
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Billing Code Overview
CPT code 87153 describes a laboratory service in which a lab analyst performs analysis using nucleic acid sequencing methods on a previously isolated and identified organism to categorize the organism more specifically, such as to the taxonomic level of type. This service is a molecular sequencing-based organism characterization performed on cultured isolates or previously identified specimens.
Service type: Microbiology / Molecular Diagnostic Sequencing
Typical site of service: Clinical laboratory or hospital pathology laboratory
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