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    OpenPayerBilling CodesHematology and Coagulation ProceduresCPT cpt-85055-reticulated-platelet-percentage
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    CPT 85055: Reticulated Platelet Percentage Assessment

    CPT code 85055 describes a laboratory test in which a lab analyst evaluates a blood specimen to determine the percentage of reticulated platelets present; the service is a hematology diagnostic platelet reticulocyte assessment typically performed in clinical laboratories or hospital lab settings on peripheral blood samples.

    For related coverage guidance, see recent payer policy updates: Epithelial Cell Cytology in Breast Cancer Risk Assessment, Chemotherapy Observation or Inpatient Hospitalization (for New Mexico Only), Umbilical Cord Blood Harvesting and Storage for Future Use (for Indiana Only).

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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is a 56-year-old individual with thrombocytopenia of unclear etiology admitted for hematology evaluation after routine complete blood count shows low platelet count and symptoms such as petechiae or easy bruising. The hematology team orders reticulated platelet testing to assess marrow platelet production and help differentiate peripheral destruction from decreased production. A phlebotomist collects a peripheral whole blood specimen in EDTA tube and sends it to the clinical laboratory. The lab analyst performs flow cytometry or automated reticulated platelet analysis to determine the percentage of immature (reticulated) platelets. Results are reported to the ordering hematologist and included in the electronic medical record; they contribute to decisions about bone marrow biopsy, immune thrombocytopenia treatment, or supportive care (transfusion) planning.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    85025Blood count; complete (CBC) with automated differential WBC and automated platelet countOften ordered before or alongside reticulated platelet testing to quantify thrombocytopenia and provide baseline indices.
    85027Blood count; automated platelet count, blood film review, and platelet estimateAlternate platelet quantification method used in parallel to reticulated platelet percentage for clinical correlation.
    85379Platelet function testing (e.g., PFA-100)Performed when platelet function, rather than platelet production, is under evaluation; may occur in the same diagnostic workup.
    85049Blood smear, interpretation by a physician (morphology)Peripheral smear review complements reticulated platelet results to assess platelet morphology and presence of schistocytes or platelet clumping.
    36592Collection of blood specimen from an implanted port, excludes lab testingMay be used if the specimen is drawn from a central access device for laboratory testing including reticulated platelets.

    Related Modifiers

    7 rows

    ModifierDescriptionWhen to Use
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    90Modifier ‑90 (Reference/Outside Laboratory) indicates that a laboratory test was performed by an entity other than the treating or reporting provider. The American Medical Association defines…- Use CPT modifier -90 when a laboratory test is performed by an outside/reference laboratory (an entity other than the treating or reporting physician or qualified professional) and the claim needs…
    91Modifier 91 — “Repeat Clinical Diagnostic Laboratory Test” — is appended when the exact same CPT laboratory test is performed more than once for the same patient on the same day because serial,…- Use modifier 91 when the exact same CPT laboratory test is performed more than once on the same patient on the same date because serial or repeated testing is medically necessary to monitor…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…

    Related Provider Taxonomies

    8 rows

    Taxonomy CodeSpecialtyNotes
    207RH0000XHematology (Internal Medicine) PhysicianAn internist with additional training who specializes in diseases of the blood, spleen and lymph. This specialist treats conditions such as anemia, cl…
    208D00000XGeneral Practice PhysicianA physician who specializes in the general practice of diagnosing, treating, and managing patients with a variety of illnesses and conditions.
    363L00000XNurse Practitioner(1) A registered nurse provider with a graduate degree in nursing prepared for advanced practice involving independent and interdependent decision mak…
    207K00000XAllergy & Immunology PhysicianAn allergist-immunologist is trained in evaluation, physical and laboratory diagnosis, and management of disorders involving the immune system. Select…
    261QM1300XMulti-Specialty Clinic/CenterAmbulatory Health Care Facilities · Clinic/Center
    390200000XStudent in an Organized Health Care Education/Training ProgramAn individual who is enrolled in an organized health care education/training program leading to a degree, certification, registration, and/or licensur…
    207RH0003XHematology & Oncology PhysicianAn internist doctor of osteopathy that specializes in the treatment of the combination of hematology and oncology disorders. A doctor of osteopathy t…
    163WP0200XPediatric Registered NurseNursing Service Providers · Registered Nurse

    Related ICD-10-CM Codes

    26 rows

    ICD-10-CM CodeDescription
    C91.10Chronic lymphocytic leukemia of B-cell type not having achieved remission
    C92.10Chronic myeloid leukemia, BCR/ABL-positive, not having achieved remission
    C95.90Leukemia, unspecified not having achieved remission
    D46.9Myelodysplastic syndrome, unspecified
    D50.9Iron deficiency anemia, unspecified
    D53.9Nutritional anemia, unspecified
    D57.1Sickle-cell disease without crisis
    D61.9Aplastic anemia, unspecified
    D63.0Anemia in neoplastic disease
    D64.9Anemia, unspecified

    Showing 1–10 of 26

    Related Payer Policy Updates

    Specialty: Hematology/Oncology1 / 3

    10 rows

    PolicyPayerEffective Date
    Epithelial Cell Cytology in Breast Cancer Risk AssessmentOscar Health2026-10-01
    Chemotherapy Observation or Inpatient Hospitalization (for New Mexico Only)UnitedHealthcare2026-08-01
    Umbilical Cord Blood Harvesting and Storage for Future Use (for Indiana Only)UnitedHealthcare2026-08-01
    Antibody-Drug ConjugatesPremera Bluecross2026-08-01
    Chimeric Antigen Receptor (CAR) T-Cell TherapyColorado Rocky Mountain Health Plans2026-08-01
    Allogeneic Hematopoietic Progenitor Cell TherapyAmbetter Georgia2026-08-01
    Umbilical Cord Blood Harvesting and Storage for Future Use (for Idaho Only)UnitedHealthcare2026-08-01
    Umbilical Cord Blood Harvesting and Storage for Future Use (for New Jersey Only)UnitedHealthcare2026-08-01
    Umbilical Cord Blood Harvesting and Storage for Future Use (for Ohio Only)UnitedHealthcare2026-08-01
    Reblozyl (luspatercept-aamt) Medical Benefit Drug PolicyUnitedHealthcare2026-08-01

    Related Codes

    CPT-85002-BLEEDING-TIME-TEST-LABORATORY

    CPT 85002: Bleeding Time Test, Technical Component

    CPT-85004-AUTOMATED-DIFFERENTIAL-WHITE-BLOOD-CELL-COUNT

    CPT 85004: Automated White Blood Cell Differential

    CPT-85007-MANUAL-DIFFERENTIAL-WHITE-BLOOD-CELL-COUNT

    CPT 85007: Manual Differential White Blood Cell Count

    CPT-85008-BLOOD-SMEAR-MORPHOLOGIC-REVIEW-NO-DIFFERENTIAL

    CPT 85008: Microscopic Blood Smear Examination, No Differential

    CPT-85009-MANUAL-WBC-COUNT-BUFFY-COAT

    CPT 85009: Manual White Blood Cell Count Using Buffy Coat

    CPT-85013-MICROHEMATOCRIT-TEST-LABORATORY-DIAGNOSTIC

    CPT 85013: Microhematocrit Test by Tube Centrifugation

    CPT-85014-HEMATOCRIT-VOLUME-PERCENT-RED-BLOOD-CELLS

    CPT 85014: Hematocrit (Volume Percent of Red Blood Cells)

    CPT-85018-HEMOGLOBIN-ASSAY-WHOLE-BLOOD

    CPT 85018: Hemoglobin Measurement in Whole Blood

    CPT-85025-COMPLETE-BLOOD-COUNT-CBC

    CPT 85025: Complete Blood Count (CBC)

    CPT-85027-COMPLETE-BLOOD-COUNT-HGB-HCT

    CPT 85027: Complete Blood Count with Hemoglobin and Hematocrit

    Showing 1–10 of 99

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    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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