CPT code 82274 identifies the fecal immunochemical test (FIT), an immunoassay used to detect occult blood in stool specimens. FIT is a widely used, noninvasive screening tool for colorectal bleeding and colorectal cancer screening programs. Nationally, FIT is important because it supports population-level screening, early detection of colorectal pathology, and can reduce the need for more invasive diagnostic procedures when negative.

Key payers discussed include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Coverage policies and reimbursement rates for laboratory services such as FIT influence screening access, clinical workflow for specimen collection (home collection versus in-office), and lab billing practices across payers.

This publication summarizes clinical context, service and site of service considerations, and payer coverage landscape. Readers will find concise benchmarks for typical use of FIT, guidance on where the service is commonly provided, and a synthesis of payer approaches and policy updates affecting lab reimbursement and access. The report focuses on national-level implications for clinicians, laboratories, and billing teams. Data not available in the input is noted where applicable.