CPT code 81186 describes a laboratory molecular genetic test in which a lab analyst performs the technical component to detect specific variants in the androgen receptor gene (also referenced as CACNA1A in this description) related to Kennedy disease or patterns of X chromosome inactivation, using a targeted, family-specific variant assay; the service type is targeted genetic testing and the typical site of service is a clinical molecular diagnostics laboratory where specimen processing and analytic testing occur.

For related coverage guidance, see recent payer policy updates: RTM Testing of Homocysteine Metabolism-Related Conditions, Multimarker Serum Testing Related to Ovarian Cancer, Genomic Profiling for Selecting Targeted Cancer Therapies.