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    OpenPayerBilling CodesMedical Radiation Physics, Dosimetry, Treatment Devices, and Special Services for Radiation TreatmentCPT cpt-77301-intensity-modulated-radiotherapy-imrt-delivery
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    CPT 77301: Intensity-Modulated Radiotherapy (IMRT) Delivery

    Medicare pays $1364 on average nationally for this procedure.

    CPT code 77301 describes the delivery of intensity-modulated radiotherapy (IMRT), a computer-controlled external beam radiation technique that shapes and modulates multiple radiation beams using three-dimensional CT-based planning to target tumors while sparing surrounding healthy tissue; the service is radiation therapy delivery typically performed in an outpatient radiation oncology clinic or hospital-based radiation therapy department for treatment of cancers such as head and neck, prostate, lung, gastrointestinal, thyroid, and breast.

    For related coverage guidance, see recent payer policy updates: Radiation oncology coverage and treatment delivery guidelines, Proton Beam Therapy, Radiation and Oncologic Procedures.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 64-year-old male with newly diagnosed locally advanced prostate adenocarcinoma is referred to radiation oncology for definitive treatment. After multidisciplinary discussion and simulation CT, the patient undergoes treatment planning using intensity modulated radiotherapy to spare adjacent organs at risk (rectum, bladder, penile bulb) while escalating dose to the prostate and seminal vesicles. The clinical workflow includes consultation and informed consent, CT simulation with immobilization devices, target and normal tissue contouring, inverse planning and dose optimization by the dosimetrist and medical physicist, plan QA (including secondary dose calculation and phantom or chart checks), and daily image-guided treatment delivery over multiple fractions. Typical sites of service are outpatient hospital-based radiation oncology departments or free-standing radiation therapy centers. Common clinical scenarios for 77301 include treatment of head and neck, prostate, lung, gastrointestinal, thyroid, and breast malignancies where conformal modulation of beam intensity reduces dose to surrounding normal tissues.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    77295Special physics consultationUsed for complex physics review or special dosimetric calculations associated with IMRT planning.
    77336Continuing medical physics consultation, per weekUsed for ongoing physics management and weekly chart review during IMRT treatment course.
    77427Radiation treatment management, 5 treatmentsUsed for radiation oncologist weekly management visits and care coordination during an IMRT course.
    G6015(If applicable) Image-guided radiation therapy (IGRT) setupUsed for image guidance procedures that accompany daily IMRT delivery (note: some payers use CPT 77387 for special IMRT QA).
    77338Special treatment procedures (e.g., IMRT dose painting, complex planning)Used when additional complex planning or special procedures are required beyond standard IMRT planning.

    Related Modifiers

    10 rows

    ModifierDescriptionWhen to Use
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    80CPT® Modifier 80 (Assistant Surgeon) is appended to a surgical CPT code when a physician (MD or DO) provides full, continuous assistance throughout the operative procedure. It is intended only for…- Use CPT Modifier -80 when a physician (MD or DO) serves as an assistant surgeon and provides full, continuous assistance throughout the entire operative procedure; append -80 to the surgical CPT…
    95Modifier 95 indicates that a service was provided via synchronous, real‑time audio‑video telehealth rather than in‑person. Per CMS, AAPC and professional associations, append modifier 95 to claim…- Use modifier 95 to indicate a service was furnished via synchronous, real‑time audiovisual telehealth (a live audio‑video conference between patient and provider) rather than in‑person. - Pair…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    174H00000X
    207RG0300X
    3336C0003X
    208D00000X
    261QR0400X
    2472B0301X
    2086S0122X
    111NX0100X

    Related ICD-10-CM Codes

    26 rows

    ICD-10-CM CodeDescription
    C11.9Malignant neoplasm of nasopharynx, unspecified
    C15.9Malignant neoplasm of esophagus, unspecified
    C16.9Malignant neoplasm of stomach, unspecified
    C18.9Malignant neoplasm of colon, unspecified
    C20Malignant neoplasm of rectum
    C22.0Liver cell carcinoma
    C25.9Malignant neoplasm of pancreas, unspecified
    C30.0Malignant neoplasm of nasal cavity
    C32.9Malignant neoplasm of larynx, unspecified
    C33Malignant neoplasm of trachea

    Showing 1–10 of 26

    Related Payer Policy Updates

    Specialty: Radiation Oncology1 / 2

    10 rows

    PolicyPayerEffective Date
    Radiation oncology coverage and treatment delivery guidelinesevicore2026-11-05
    Proton Beam Therapyuniversityofutahhealthplans2026-10-25
    Radiation and Oncologic ProceduresUnitedHealthcare2026-09-01
    Electronic Brachytherapy for Nonmelanoma Skin CancerBluecross Idaho2026-07-30
    Surface Radiation Therapy for Treatment of Non-Melanoma Skin Cancereocco2026-07-09
    Radiofrequency Ablation of Tumors Outside the LiverProvidence Health Plan2026-07-01
    Therapeutic Radiopharmaceuticals in Oncology (Lutathera, Pluvicto, Xofigo) Coverage CriteriaBlue Cross Blue Shield - North Carolina2026-07-01
    Intensity Modulated Radiation TherapyAmbetter Georgia2026-06-01
    Irreversible Electroporation (IRE) of Tumors Other Than LiverBlue Cross Blue Shield - Rhode Island2026-06-01
    Irreversible Electroporation (IRE) — NanoKnife (Preauthorization Required)Blue Cross Blue Shield - Nebraska2026-06-01

    Related Codes

    CPT-77300-RADIATION-THERAPY-DOSIMETRY

    CPT 77300: Radiation Dosimetry and Treatment Planning

    CPT-77306-RADIATION-THERAPY-BEAM-ARRANGEMENT-DOSE-CALCULATION

    CPT 77306: Parallel Opposed External Beam Radiation Treatment Setup

    CPT-77307-RADIATION-THERAPY-ISODOSE-TANGENTIAL-PORT-PLANNING

    CPT 77307: Tangential Ports and Isodose Beam Arrangement for Radiation Therapy

    CPT-77316-BRACHYTHERAPY-SIMPLE-ISODOSE-PLANNING

    CPT 77316: Simple Level Isodose Planning for Brachytherapy

    CPT-77317-INTERMEDIATE-BRACHYTHERAPY-ISODOSE-PLANNING

    CPT 77317: Intermediate Isodose Planning for Brachytherapy

    CPT-77318-INTERMEDIATE-ISODOSE-BRACHYTHERAPY-PLANNING

    CPT 77318: Brachytherapy Isodose Planning, Intermediate

    CPT-77321-ELECTRON-SPECIAL-BEAM-PLANNING-RADIATION-ONCOLOGY

    CPT 77321: Radiation Therapy Planning — Special Beam Consideration

    CPT-77331-SPECIAL-DOSIMETRY-RADIATION-DOSE-CALCULATION

    CPT 77331: Special Dosimetry and Radiation Monitoring

    CPT-77332-SIMPLE-TREATMENT-DEVICE-DESIGN-SELECTION

    CPT 77332: Simple Treatment Device Design and Selection

    CPT-77333-RADIATION-THERAPY-INTERMEDIATE-DEVICE-DESIGN

    CPT 77333: Design/Construction of Intermediate Radiation Therapy Devices

    Showing 1–10 of 14

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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