CPT code 62281 denotes an interventional pain-management procedure in which a neurolytic agent is injected or infused into the epidural space at the cervical or thoracic level, sometimes with an additional therapeutic drug. This procedure is used to provide durable pain relief in severe, acute, or cancer-related pain and following traumatic events such as limb amputation. Nationally, this code represents a specialized, high-acuity service often performed in hospital outpatient departments, ambulatory surgical centers, or other procedural settings equipped for epidural interventions.

Key payers covered in this analysis include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find clinical context for when the service is used, comparisons of common payer coverage patterns, and benchmarks where available. The report summarizes coding and service-line considerations, typical settings of care, and relevant policy themes affecting access and payment for neurolytic epidural procedures. Data not available in the input are explicitly noted where applicable.