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    v1.0.28
    OpenPayerBilling CodesExcision Procedures on the Vulva, Perineum and IntroitusCPT cpt-56633-radical-vulvectomy-surgical-oncology
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    CPT 56633: Radical Vulvectomy for Malignant Disease

    Medicare pays $1166 on average nationally for this procedure.

    CPT code 56633 describes a radical vulvectomy performed for malignant disease of the vulva, involving removal of all or part of the vulva and adjacent tissue; the procedure may include lymph node removal and partial or total clitorectomy depending on disease extent. Service type: radical surgical excision for malignancy. Typical site of service: hospital inpatient or outpatient surgical suite for gynecologic oncology procedures.

    For related coverage guidance, see recent payer policy updates: Prolonged Services for Labor Management, Prolonged Services for Labor Management, Cervical Cancer Screening.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is a postmenopausal woman presenting with a vulvar lesion that biopsy confirms as invasive squamous cell carcinoma of the vulva. The patient undergoes preoperative staging with pelvic exam, imaging (pelvic MRI or CT), and counseling about surgical options. The surgical team—typically a gynecologic oncologist with support from anesthesiology and perioperative nursing—performs a 56633 radical vulvectomy under general anesthesia to remove the primary tumor with wide margins. The procedure may include partial or complete removal of the clitoris and adjacent soft tissue and can be combined with uni- or bilateral inguinal-femoral lymphadenectomy when indicated. Intraoperative frozen section pathology may be used to assess margins. Postoperative care includes pain control, wound care, venous thromboembolism prophylaxis, and coordination of adjuvant therapy if pathology indicates. Typical sites of service are an outpatient surgical center for select cases or an inpatient hospital operating room when lymphadenectomy, reconstruction, comorbidities, or planned observation are anticipated.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    38746Excision, tumor, groin and/or pelvic region; superficial, single lesionMay be used for excision of superficial inguinal lymph node metastasis when separate from formal lymphadenectomy performed with 56633.
    38740Lymphadenectomy, inguinal, superficial; completeCommonly performed concurrently when nodal staging or removal of involved inguinal nodes is indicated with radical vulvectomy.
    19318Reduction mammoplasty, pedicle techniqueWhile not directly related to vulvectomy, reconstructive procedures for genital soft-tissue defects may require plastic surgery codes; reconstructive codes are billed in coordination when flap or reconstruction is performed after 56633.
    88305Level IV surgical pathology, gross and microscopic examinationUsed for pathologic evaluation of excised vulvar specimens and lymph nodes from 56633.
    99024Postoperative follow-up visit, commonly for routine postoperative careUsed for global period postoperative visits following 56633 when billed separately per payer rules.

    Related Modifiers

    12 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    66Modifier 66 (Surgical Team) is used when three or more surgeons act as primary surgeons on a single, highly complex procedure. The AMA defines it for use when a surgical team — often composed of…- Use modifier 66 when three or more surgeons act as primary surgeons working collaboratively as a surgical team on a single, highly complex or difficult procedure (for example organ…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    80CPT® Modifier 80 (Assistant Surgeon) is appended to a surgical CPT code when a physician (MD or DO) provides full, continuous assistance throughout the operative procedure. It is intended only for…- Use CPT Modifier -80 when a physician (MD or DO) serves as an assistant surgeon and provides full, continuous assistance throughout the entire operative procedure; append -80 to the surgical CPT…

    Showing 1–10 of 12

    Related Provider Taxonomies

    8 rows

    Taxonomy CodeSpecialtyNotes
    208100000XPhysical Medicine & Rehabilitation PhysicianPhysical medicine and rehabilitation, also referred to as rehabilitation medicine, is the medical specialty concerned with diagnosing, evaluating, and…
    2086S0122XPlastic and Reconstructive Surgery PhysicianA surgeon who specializes in plastic and reconstructive surgery.
    207R00000XInternal Medicine PhysicianA physician who provides long-term, comprehensive care in the office and the hospital, managing both common and complex illness of adolescents, adults…
    2084P0800XPsychiatry PhysicianA Psychiatrist specializes in the prevention, diagnosis, and treatment of mental disorders, emotional disorders, psychotic disorders, mood disorders, …
    363L00000XNurse Practitioner(1) A registered nurse provider with a graduate degree in nursing prepared for advanced practice involving independent and interdependent decision mak…
    2084P0005XNeurodevelopmental Disabilities PhysicianA neurologist who specializes in the treatment of individuals with developmental delays and learning disorders associated with cerebral palsy, spina b…
    2084N0600XClinical Neurophysiology PhysicianClinical Neurophysiology is a subspecialty with psychiatric or neurologic expertise in the diagnosis and management of central, peripheral, and autono…
    261QF0050XNon-Surgical Family Planning Clinic/CenterAn entity, facility, or distinct part of a facility, or mobile unit providing non-surgical, family planning/reproductive services including physical e…

    Related Payer Policy Updates

    Specialty: Obstetrics/Gynecology1 / 2

    8 rows

    PolicyPayerEffective Date
    Prolonged Services for Labor ManagementPremera Bluecross2027-01-01
    Prolonged Services for Labor ManagementPremera Bluecross2027-01-01
    Cervical Cancer ScreeningOscar Health2026-10-01
    Prenatal Testing for Fetal AneuploidyOscar Health2026-10-01
    Diagnosis of VaginitisOscar Health2026-10-01
    Prenatal Screening (Nongenetic)Oscar Health2026-10-01
    View PDF of Maternal Serum Biomarkers for Prediction of Adverse Obstetric Outcomes, Effective 10/1/2026 in MedicalBlue Cross Blue Shield - Rhode Island2026-10-01
    Maternal Serum Testing for Prediction of Adverse Obstetric OutcomesBluecross Idaho2026-09-01

    Related Codes

    CPT-56605-VULVAR-PERINEAL-LESION-EXCISION-BIOPSY

    CPT 56605: Excision of Single Vulvar or Perineal Lesion

    CPT-56606-EXCISION-VULVA-PERINEUM-ADDITIONAL-LESIONS

    CPT 56606: Excision of Additional Vulvar or Perineal Lesions

    CPT-56620-SIMPLE-VULVECTOMY-GYNECOLOGIC-EXCISION

    CPT 56620: Simple Vulvectomy for Benign or Premalignant Vulvar Conditions

    CPT-56625-SIMPLE-VULVECTOMY-GYNECOLOGIC-SURGERY

    CPT 56625: Simple Vulvectomy for Benign or Premalignant Vulvar Disease

    CPT-56630-RADICAL-VULVECTOMY-MAJOR-ONCOLOGIC-SURGERY

    CPT 56630: Radical Vulvectomy for Malignant Disease

    CPT-56631-RADICAL-VULVECTOMY-UNILATERAL-INGUINOFEMORAL-NODE

    CPT 56631: Radical Vulvectomy with Unilateral Inguinofemoral Lymph Node Dissection

    CPT-56632-RADICAL-VULVECTOMY-WITH-INGUINOFEMORAL-LYMPH-NODE-DISSECTION

    CPT 56632: Radical Vulvectomy with Bilateral Inguinofemoral Lymphadenectomy

    CPT-56634-RADICAL-VULVECTOMY-INGUINOFEMORAL-LYMPH-NODE

    CPT 56634: Radical Vulvectomy with Unilateral Inguinofemoral Lymph Node Removal

    CPT-56637-RADICAL-VULVECTOMY-WITH-BILATERAL-LYMPHADENECTOMY

    CPT 56637: Radical Vulvectomy with Inguinofemoral Lymphadenectomy

    CPT-56640-RADICAL-VULVECTOMY-WITH-LYMPHADENECTOMY

    CPT 56640: Radical Vulvectomy with Lymph Node Dissection

    Showing 1–10 of 12

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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