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    v1.0.28
    OpenPayerBilling CodesExcision Procedures on the Vulva, Perineum and IntroitusCPT cpt-56625-simple-vulvectomy-gynecologic-surgery
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    CPT 56625: Simple Vulvectomy for Benign or Premalignant Vulvar Disease

    Medicare pays $632 on average nationally for this procedure.

    CPT code 56625 describes a simple vulvectomy, a surgical procedure to remove all or part of the vulva for benign or premalignant conditions when lesions are extensive or numerous and cannot be managed by local excision; the service is a surgical excision typically performed in an operating room or ambulatory surgery center under appropriate anesthesia and involves complete removal of affected vulvar tissue to treat widespread disease.

    For related coverage guidance, see recent payer policy updates: Prolonged Services for Labor Management, Prolonged Services for Labor Management, Cervical Cancer Screening.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is a woman in her 50s–70s presenting with extensive symptomatic vulvar lesions such as widespread lichen sclerosus with scarring, multifocal high‑grade vulvar intraepithelial neoplasia, or large premalignant vulvar lesions not amenable to local excision. The clinical workflow begins with outpatient evaluation by a gynecologist or gynecologic oncologist including history, focused pelvic and vulvar exam, and biopsy of representative lesions. Preoperative workup includes medical optimization, informed consent discussing extent of resection and reconstructive options, and anesthesia evaluation. The procedure 56625 (simple vulvectomy) is performed in an ambulatory surgery center or hospital operating room under regional or general anesthesia. Intraoperative steps include marking of planned resection, excision of involved vulvar skin and subcutaneous tissue to the appropriate depth, hemostasis, and primary closure or local flap reconstruction as indicated. Postoperative care includes pain control, wound care instructions, short inpatient observation if needed, and outpatient follow‑up for pathology review and wound assessment. Common clinical scenarios include failure of conservative therapy for chronic vulvar disease, multifocal premalignant lesions where local excision is impractical, or extensive benign conditions causing functional impairment.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    11102Tangential biopsy of skin of single lesion, up to 4 lesionsPerformed preoperatively to diagnose suspicious vulvar lesions before planning a vulvectomy.
    11100Shave biopsy of skin, single lesionAlternative diagnostic sampling technique for superficial vulvar lesions prior to definitive excision.
    19120Excision of cyst of vulva or labia (Note: code example for minor vulvar excisions)Performed for smaller localized benign vulvar lesions that may be alternatives to a simple vulvectomy.
    56405Local excision or destruction of lesion of vulva; simpleUsed for discrete vulvar lesion excision when less extensive than 56625.
    57260Colpoplasty, repair of pelvic organ prolapse (anterior/posterior)May be performed concurrently if pelvic floor repair or reconstructive needs arise after extensive vulvar resection.
    15734Muscle, myocutaneous or fasciocutaneous flap; trunk (eg, gracilis)Used when flap reconstruction is required after large vulvar resections; billed adjunctively when applicable.

    Related Modifiers

    13 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    54Modifier ‑54 (“Surgical care only”) is appended to a CPT surgical procedure when the reporting surgeon performs the intraoperative (surgical) component but does not furnish the preoperative and/or…- Use modifier -54 when the reporting surgeon provided only the intraoperative (surgical) component of a procedure and preoperative and/or postoperative management has been or will be provided by…
    55Modifier –55 indicates the billing provider furnished only postoperative management for a procedure that has a global surgical period. According to AAPC, this modifier is appended to the same CPT…- Use modifier -55 when billing the same CPT surgical code that has a 10- or 90-day global period and you, as a provider other than the original surgeon, furnished ONLY postoperative management (no…
    56Modifier ‑56 indicates the reporting provider furnished only the preoperative management for a surgical procedure and did not perform the intraoperative or postoperative care. It is used in…- Use Modifier -56 when a provider performs only the preoperative management in a split‑care situation (one physician manages preop care while a different physician performs the intraoperative…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    63Modifier‑63 is appended to surgical CPT codes (20000–69990) when a procedure is performed on a neonate or infant weighing ≤ 4 kg (about 8.8 lbs). The AMA/AAPC definition specifies this use and notes…- Use modifier -63 only for surgical procedures in the CPT 20000–69990 series performed on a neonate or infant who weighs ≤ 4 kg at the time of the procedure; it indicates increased complexity due to…
    66Modifier 66 (Surgical Team) is used when three or more surgeons act as primary surgeons on a single, highly complex procedure. The AMA defines it for use when a surgical team — often composed of…- Use modifier 66 when three or more surgeons act as primary surgeons working collaboratively as a surgical team on a single, highly complex or difficult procedure (for example organ…

    Showing 1–10 of 13

    Related Provider Taxonomies

    8 rows

    Taxonomy CodeSpecialtyNotes
    207V00000XObstetrics & Gynecology PhysicianAn obstetrician/gynecologist possesses special knowledge, skills and professional capability in the medical and surgical care of the female reproducti…
    2080P0006XDevelopmental - Behavioral Pediatrics PhysicianA developmental-behavioral specialist is a pediatrician with special training and experience who aims to foster understanding and promotion of optimal…
    207Q00000XFamily Medicine PhysicianFamily Medicine is the medical specialty which is concerned with the total health care of the individual and the family. It is the specialty in breadt…
    2084P0800XPsychiatry PhysicianA Psychiatrist specializes in the prevention, diagnosis, and treatment of mental disorders, emotional disorders, psychotic disorders, mood disorders, …
    246QM0900XMicrobiology Specialist/TechnologistTechnologists, Technicians & Other Technical Service Providers · Specialist/Technologist, Pathology
    2471B0102XBone Densitometry Radiologic TechnologistA radiologic technologist who specializes in bone densitometry and is appropriately educated and trained, consistent with nationally recognized standa…
    246Z00000XOther Specialist/TechnologistGeneral classification identifying individuals trained on specific equipment and technical procedures in one of a collection of miscellaneous healthca…
    261QR0400XRehabilitation Clinic/CenterAmbulatory Health Care Facilities · Clinic/Center

    Related Payer Policy Updates

    Specialty: Obstetrics/Gynecology1 / 2

    8 rows

    PolicyPayerEffective Date
    Prolonged Services for Labor ManagementPremera Bluecross2027-01-01
    Prolonged Services for Labor ManagementPremera Bluecross2027-01-01
    Cervical Cancer ScreeningOscar Health2026-10-01
    Prenatal Testing for Fetal AneuploidyOscar Health2026-10-01
    Diagnosis of VaginitisOscar Health2026-10-01
    Prenatal Screening (Nongenetic)Oscar Health2026-10-01
    View PDF of Maternal Serum Biomarkers for Prediction of Adverse Obstetric Outcomes, Effective 10/1/2026 in MedicalBlue Cross Blue Shield - Rhode Island2026-10-01
    Maternal Serum Testing for Prediction of Adverse Obstetric OutcomesBluecross Idaho2026-09-01

    Related Codes

    CPT-56605-VULVAR-PERINEAL-LESION-EXCISION-BIOPSY

    CPT 56605: Excision of Single Vulvar or Perineal Lesion

    CPT-56606-EXCISION-VULVA-PERINEUM-ADDITIONAL-LESIONS

    CPT 56606: Excision of Additional Vulvar or Perineal Lesions

    CPT-56620-SIMPLE-VULVECTOMY-GYNECOLOGIC-EXCISION

    CPT 56620: Simple Vulvectomy for Benign or Premalignant Vulvar Conditions

    CPT-56630-RADICAL-VULVECTOMY-MAJOR-ONCOLOGIC-SURGERY

    CPT 56630: Radical Vulvectomy for Malignant Disease

    CPT-56631-RADICAL-VULVECTOMY-UNILATERAL-INGUINOFEMORAL-NODE

    CPT 56631: Radical Vulvectomy with Unilateral Inguinofemoral Lymph Node Dissection

    CPT-56632-RADICAL-VULVECTOMY-WITH-INGUINOFEMORAL-LYMPH-NODE-DISSECTION

    CPT 56632: Radical Vulvectomy with Bilateral Inguinofemoral Lymphadenectomy

    CPT-56633-RADICAL-VULVECTOMY-SURGICAL-ONCOLOGY

    CPT 56633: Radical Vulvectomy for Malignant Disease

    CPT-56634-RADICAL-VULVECTOMY-INGUINOFEMORAL-LYMPH-NODE

    CPT 56634: Radical Vulvectomy with Unilateral Inguinofemoral Lymph Node Removal

    CPT-56637-RADICAL-VULVECTOMY-WITH-BILATERAL-LYMPHADENECTOMY

    CPT 56637: Radical Vulvectomy with Inguinofemoral Lymphadenectomy

    CPT-56640-RADICAL-VULVECTOMY-WITH-LYMPHADENECTOMY

    CPT 56640: Radical Vulvectomy with Lymph Node Dissection

    Showing 1–10 of 12

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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