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    OpenPayerBilling CodesExcision Procedures on the Seminal VesiclesCPT cpt-55680-mullerian-duct-cyst-excision-seminal-vesicle
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    CPT 55680: Excision of Mullerian Duct Cyst, Seminal Vesicle

    Medicare pays $329 on average nationally for this procedure.

    CPT code 55680 describes surgical excision of a Müllerian duct cyst within the seminal vesicle complex; this is a procedural code for removal of an embryologic cystic remnant causing genitourinary symptoms. The service type is surgical excision, typically performed in an operating room or procedural suite with regional or general anesthesia and appropriate perioperative care in a hospital or ambulatory surgical center setting.

    For related coverage guidance, see recent payer policy updates: Removal of Implantable, Outpatient Surgical Procedures - Site of Service, Surgical Procedures.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 34-year-old male presents with recurrent perineal pain, ejaculatory discomfort, and episodes of hematospermia. Imaging with transrectal ultrasound and pelvic MRI identifies a midline Mullerian duct (prostatic utricle/seminal vesicle) cyst measuring 2.5 cm with mass effect on the ejaculatory ducts. Conservative management including antibiotics and image-guided aspiration provided only temporary relief. Urology schedules a transperineal or transvesical surgical excision of the Mullerian duct cyst under general anesthesia. Preoperative workflow includes informed consent, baseline labs, anesthesia evaluation, and intraoperative cyst excision with possible intraoperative cystoscopy to evaluate urethra and ejaculatory duct patency. Postoperative care includes short inpatient observation or same-day discharge depending on intraoperative findings and patient stability, pain control, and a follow-up visit with pelvic ultrasound or MRI if symptoms persist.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    52000Cystourethroscopy, with or without calibration and/or dilation (separate procedure)Performed preoperatively or intraoperatively to evaluate urethra, prostatic urethra, and ejaculatory duct patency related to a Mullerian duct cyst.
    52224Cystourethroscopy with fulguration or excision of lesions of the bladder neck or urethra (separate procedure)May be used if additional intraluminal lesions are treated during cystoscopy related to the index pathology.
    55866Laparoscopy, surgical; with radical prostatectomy (complex pelvic laparoscopic work)Shares pelvic laparoscopic approach coding principles; referenced when minimally invasive pelvic approaches are used for seminal vesicle/Mullerian duct excision.
    49320Laparoscopy, surgical; diagnostic, with or without collection of specimen(s) by biopsyMay be billed if a diagnostic laparoscopy is performed to assess pelvic anatomy prior to definitive excision.
    38500Biopsy or excision of lymph node(s); open, superficialBilled if concurrent nodal sampling is performed during open pelvic surgery for suspicious lymphadenopathy.

    Related Modifiers

    12 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    66Modifier 66 (Surgical Team) is used when three or more surgeons act as primary surgeons on a single, highly complex procedure. The AMA defines it for use when a surgical team — often composed of…- Use modifier 66 when three or more surgeons act as primary surgeons working collaboratively as a surgical team on a single, highly complex or difficult procedure (for example organ…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    80CPT® Modifier 80 (Assistant Surgeon) is appended to a surgical CPT code when a physician (MD or DO) provides full, continuous assistance throughout the operative procedure. It is intended only for…- Use CPT Modifier -80 when a physician (MD or DO) serves as an assistant surgeon and provides full, continuous assistance throughout the entire operative procedure; append -80 to the surgical CPT…

    Showing 1–10 of 12

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    208U00000X
    2080P0006X
    208VP0000X
    207R00000X
    207L00000X
    133VN1004X
    246XS1301X
    253J00000X

    Related Payer Policy Updates

    Specialty: General Surgery1 / 2

    10 rows

    PolicyPayerEffective Date
    Removal of ImplantableBlue Cross Blue Shield - Rhode Island2026-10-01
    Outpatient Surgical Procedures - Site of ServiceUnitedHealthcare2026-09-01
    Surgical ProceduresUnitedHealthcare2026-09-01
    Site of Service Ambulatory Service Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Site of Service for Ambulatory Surgical Procedures (ASC Select)Premera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Medical Necessity Guidelines Inpatient Surgical CareMass General Brigham Health Plan2026-08-01
    Outpatient Surgical Procedures - Site of Servicesierra health and life2026-08-01

    Related Codes

    CPT-55650-EXCISION-SEMINAL-VESICLES

    CPT 55650: Excision of Seminal Vesicles for Lesion or Infection

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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