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    OpenPayerBilling CodesExcision Procedures on the Seminal VesiclesCPT cpt-55650-excision-seminal-vesicles
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    CPT 55650: Excision of Seminal Vesicles for Lesion or Infection

    Medicare pays $664 on average nationally for this procedure.

    CPT code 55650 describes surgical excision of the seminal vesicles performed for a lesion or infection; this is a surgical procedure typically done in an operating room or other inpatient/outpatient surgical setting by a urologic surgeon and involves removal of one or both seminal vesicles to treat localized disease or refractory infection.

    For related coverage guidance, see recent payer policy updates: Removal of Implantable, Outpatient Surgical Procedures - Site of Service, Surgical Procedures.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 52-year-old man presents with persistent pelvic pain, hematospermia, and recurrent infections despite targeted antibiotics. Imaging (transrectal ultrasound and pelvic MRI) identifies a focal lesion and chronic inflammatory changes isolated to the seminal vesicle complex. After urology consultation and counseling, the patient is scheduled for excision of the affected seminal vesicle(s) to remove the lesion and control infection.

    The clinical workflow includes preoperative evaluation (history, exam, PSA testing if indicated), imaging to localize the lesion, informed consent discussing risks and benefits, anesthesia evaluation, intraoperative excision of the seminal vesicle(s) via open, laparoscopic, or robotic approach, specimen submission to pathology, postoperative monitoring for bleeding, infection, urinary or ejaculatory dysfunction, and outpatient follow-up for wound check and pathology review. Typical sites of service are hospital inpatient or hospital outpatient surgical departments, and ambulatory surgery centers for stable patients undergoing elective excision.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    54120Excision of ejaculatory ductMay be performed when pathology involves ductal structures adjacent to seminal vesicles
    55866Laparoscopy, surgical prostatectomy; radical, retropubic, includes nerve sparing when performedPerformed in cases where seminal vesicle excision is part of broader prostate cancer surgery
    55845Radical prostatectomy, retropubic, with or without nerve sparing; including seminal vesicle removal when includedSeminal vesicle excision is often included in radical prostatectomy for malignancy staging and clearance
    +59970Urinary catheterization, including insertion and removal when performed for surgical managementCommon adjunct for perioperative urinary drainage during recovery
    88304Surgical pathology, gross and microscopic examinationUsed for histopathologic evaluation of the excised seminal vesicle specimen

    Related Modifiers

    8 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    63Modifier‑63 is appended to surgical CPT codes (20000–69990) when a procedure is performed on a neonate or infant weighing ≤ 4 kg (about 8.8 lbs). The AMA/AAPC definition specifies this use and notes…- Use modifier -63 only for surgical procedures in the CPT 20000–69990 series performed on a neonate or infant who weighs ≤ 4 kg at the time of the procedure; it indicates increased complexity due to…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    80CPT® Modifier 80 (Assistant Surgeon) is appended to a surgical CPT code when a physician (MD or DO) provides full, continuous assistance throughout the operative procedure. It is intended only for…- Use CPT Modifier -80 when a physician (MD or DO) serves as an assistant surgeon and provides full, continuous assistance throughout the entire operative procedure; append -80 to the surgical CPT…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    208800000X
    207P00000X
    363L00000X
    207K00000X
    2080P0206X
    246QI0000X
    202K00000X
    293D00000X

    Related ICD-10-CM Codes

    17 rows

    ICD-10-CM CodeDescription
    B95.1Streptococcus, group B, as the cause of diseases classified elsewhere
    N41.0Acute prostatitis
    N41.1Chronic prostatitis
    N41.9Inflammatory disease of prostate, unspecified
    N45.3Epididymo-orchitis
    N45.4Abscess of epididymis or testis
    N48.1Balanitis
    N48.6Induration penis plastica
    N48.89Other specified disorders of penis
    N50.9Disorder of male genital organs, unspecified

    Showing 1–10 of 17

    Related Payer Policy Updates

    Specialty: General Surgery1 / 2

    10 rows

    PolicyPayerEffective Date
    Removal of ImplantableBlue Cross Blue Shield - Rhode Island2026-10-01
    Outpatient Surgical Procedures - Site of ServiceUnitedHealthcare2026-09-01
    Surgical ProceduresUnitedHealthcare2026-09-01
    Site of Service Ambulatory Service Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Site of Service for Ambulatory Surgical Procedures (ASC Select)Premera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Medical Necessity Guidelines Inpatient Surgical CareMass General Brigham Health Plan2026-08-01
    Outpatient Surgical Procedures - Site of Servicesierra health and life2026-08-01

    Related Codes

    CPT-55680-MULLERIAN-DUCT-CYST-EXCISION-SEMINAL-VESICLE

    CPT 55680: Excision of Mullerian Duct Cyst, Seminal Vesicle

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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