CPT code 54405 represents the surgical implantation of a multicomponent inflatable penile prosthesis, including placement of cylinders, pump, and reservoir. This procedure is a definitive surgical treatment for erectile dysfunction when less invasive therapies have failed and is performed in operating rooms or ambulatory surgery centers nationwide. The code’s proper use affects inpatient and outpatient surgical billing, device procurement, and payer reimbursement policies across major national payers.

Key payers addressed include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find a concise explanation of the procedure, typical sites of service, and the clinical context for use. The publication outlines common modifiers and coding considerations, payer-specific coverage patterns, and benchmarking metrics where available. It also summarizes relevant policy updates and prior-authorization trends that commonly influence use of this code.

This summary provides clinicians, coding staff, and policy analysts with the information needed to understand the clinical service represented by CPT code 54405, its role in urologic surgical care, and the payer landscape that shapes access and reimbursement nationally.