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    v1.0.28
    OpenPayerBilling CodesUrethra and Bladder Transurethral Surgical ProceduresCPT cpt-52290-cystoscopic-inspection-and-ureteral-orifice-incision
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    CPT 52290: Cystoscopy with Incision of Ureteral Orifice

    Medicare pays $219 on average nationally for this procedure.

    CPT code 52290 describes a cystoscopic procedure in which the clinician inspects the urethra, prostatic urethra (in men), bladder interior, and ureteric orifices using a cystoscope passed through the urethra, and performs an incision of one or both ureteral openings; service type: endoscopic urologic surgery; typical site of service: ambulatory surgery center or hospital operating room or procedure suite.

    For related coverage guidance, see recent payer policy updates: Prolonged Services for Labor Management, Prolonged Services for Labor Management, Cervical Cancer Screening.

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    Table of contents

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    • Billing CodesCPT, HCPCS, DRG & more
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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is an adult presenting with recurrent febrile urinary tract infections, hydronephrosis, or persistent vesicoureteral reflux (VUR) despite conservative management. A urologist evaluates the patient with history, physical exam, urinalysis, urine culture, renal ultrasound and possibly a voiding cystourethrogram. The patient is scheduled for cystoscopy with incision of the ureteral orifice (52290) under general or regional anesthesia in an outpatient urology procedure suite or ambulatory surgery center. During the procedure the provider passes a rigid or flexible cystoscope through the urethra to inspect the urethra, prostatic urethra in men, bladder interior, and the ureteric orifices. The surgeon identifies an obstructing or stenotic ureteral orifice or an abnormal intramural tunnel and performs an endoscopic incision (ureteral orifice incision or ureteroneocystostomy adjunct) to improve drainage. Intraoperative steps include cystoscopic inspection, visualization of ureteral efflux, placement of a guidewire or ureteral stent if needed, endoscopic incision of one or both ureteral orifices, hemostasis, and documentation of findings and any devices placed. Typical post-procedure workflow includes recovery from anesthesia, monitoring for hematuria or flank pain, instruction on activity limitations and stent care if placed, and scheduling follow-up imaging or cystoscopic reassessment as indicated.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    52000Cystourethroscopy, diagnostic; with or without collection of specimen(s) by brushing or washingOften performed prior to 52290 for diagnostic inspection of the bladder and urethra when no incision is needed
    52332Cystourethroscopy, with ureteroscopy; with removal of stone(s) from ureterPerformed when concomitant ureteral stones are identified during cystoscopy and require ureteroscopy/stone management
    52000Cystourethroscopy, diagnostic; with or without collection of specimen(s) by brushing or washingAlternative diagnostic cystoscopy code used for inspection without incision
    52310Cystourethroscopy with brush biopsy or washings (separate from diagnostic cystoscopy)May be performed if mucosal abnormality or tumor is identified during cystoscopic inspection
    52353Cystourethroscopy, with ureteroscopy, with removal of calculus by ureteroscopyPerformed when ureteral pathology extends beyond the orifice and requires ureteroscopic intervention
    50710Ureteral reimplantation, open or laparoscopicPerformed when endoscopic incision (52290) is insufficient and formal reimplantation is required

    Related Modifiers

    11 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    63Modifier‑63 is appended to surgical CPT codes (20000–69990) when a procedure is performed on a neonate or infant weighing ≤ 4 kg (about 8.8 lbs). The AMA/AAPC definition specifies this use and notes…- Use modifier -63 only for surgical procedures in the CPT 20000–69990 series performed on a neonate or infant who weighs ≤ 4 kg at the time of the procedure; it indicates increased complexity due to…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    80CPT® Modifier 80 (Assistant Surgeon) is appended to a surgical CPT code when a physician (MD or DO) provides full, continuous assistance throughout the operative procedure. It is intended only for…- Use CPT Modifier -80 when a physician (MD or DO) serves as an assistant surgeon and provides full, continuous assistance throughout the entire operative procedure; append -80 to the surgical CPT…
    81Modifier -81 indicates a physician served as a minimal assistant surgeon for part—not all—of an operative procedure. Use when a physician’s assisting role is limited and does not represent full…- Use CPT modifier -81 when a physician acts as a minimum assistant surgeon who assists during only part (a limited portion) of an operative procedure; append -81 to the primary surgical CPT code to…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…

    Showing 1–10 of 11

    Related Provider Taxonomies

    8 rows

    Taxonomy CodeSpecialtyNotes
    208U00000XClinical Pharmacology PhysicianClinical pharmacology encompasses the spectrum of activities related to the discovery, development, regulation, and utilization of safe and effective …
    207RC0000XCardiovascular Disease PhysicianAn internist who specializes in diseases of the heart and blood vessels and manages complex cardiac conditions such as heart attacks and life-threaten…
    2080P0207XPediatric Hematology & Oncology PhysicianA pediatrician trained in the combination of pediatrics, hematology and oncology to recognize and manage pediatric blood disorders and cancerous disea…
    207L00000XAnesthesiology PhysicianAn anesthesiologist is trained to provide pain relief and maintenance, or restoration, of a stable condition during and immediately following an opera…
    207K00000XAllergy & Immunology PhysicianAn allergist-immunologist is trained in evaluation, physical and laboratory diagnosis, and management of disorders involving the immune system. Select…
    207LP4000XPhysician Nutrition Specialist (Anesthesiology)A physician who specializes in the diagnosis and treatment of primary nutritional diseases (e.g., undernutrition, overnutrition, and genetic or acquir…
    363AS0400XSurgical Physician AssistantPhysician Assistants & Advanced Practice Nursing Providers · Physician Assistant
    207V00000XObstetrics & Gynecology PhysicianAn obstetrician/gynecologist possesses special knowledge, skills and professional capability in the medical and surgical care of the female reproducti…

    Related Payer Policy Updates

    Specialty: Obstetrics/Gynecology1 / 2

    8 rows

    PolicyPayerEffective Date
    Prolonged Services for Labor ManagementPremera Bluecross2027-01-01
    Prolonged Services for Labor ManagementPremera Bluecross2027-01-01
    Cervical Cancer ScreeningOscar Health2026-10-01
    Prenatal Testing for Fetal AneuploidyOscar Health2026-10-01
    Diagnosis of VaginitisOscar Health2026-10-01
    Prenatal Screening (Nongenetic)Oscar Health2026-10-01
    View PDF of Maternal Serum Biomarkers for Prediction of Adverse Obstetric Outcomes, Effective 10/1/2026 in MedicalBlue Cross Blue Shield - Rhode Island2026-10-01
    Maternal Serum Testing for Prediction of Adverse Obstetric OutcomesBluecross Idaho2026-09-01

    Related Codes

    CPT-52204-CYSTOURETHROSCOPY-WITH-BIOPSY

    CPT 52204: Cystourethroscopy with Biopsy

    CPT-52214-TRANSURETHRAL-BLADDER-URETHRAL-TISSUE-DESTRUCTION

    CPT 52214: Endoscopic Destruction of Bladder/Urethral Tissue

    CPT-52224-CYSTOSCOPY-LESION-DESTRUCTION-MINOR

    CPT 52224: Cystoscopy with Destruction of Minor Bladder Lesion

    CPT-52234-CYSTOSCOPIC-DESTRUCTION-SMALL-BLADDER-LESION

    CPT 52234: Cystoscopy with Destruction of Small Bladder Lesion

    CPT-52235-CYSTOSCOPIC-DESTRUCTION-MEDIUM-BLADDER-LESION-2-5CM

    CPT 52235: Cystoscopy with Fulguration of Medium Bladder Lesion

    CPT-52240-CYSTOSCOPY-LESION-FULGURATION-ABLATION-GREATER-THAN-5CM

    CPT 52240: Cystoscopy with Destruction of Bladder Lesion (>5.0 cm)

    CPT-52250-CYSTOSCOPIC-INTRAVESICAL-RADIOACTIVE-THERAPY-FOR-BLADDER-CANCER

    CPT 52250: Cystoscopy with Intravesical Radioisotope Therapy

    CPT-52260-DIAGNOSTIC-CYSTOSCOPY-INTERSTITIAL-CYSTITIS-EVALUATION

    CPT 52260: Cystoscopic Inspection Under Anesthesia for Interstitial Cystitis

    CPT-52265-DIAGNOSTIC-CYSTOSCOPY-INTERSTITIAL-CYSTITIS-EVALUATION

    CPT 52265: Diagnostic Cystoscopy for Interstitial Cystitis

    CPT-52270-CYSTOSCOPIC-URETHROTOMY-INTERNAL-URETHRAL-STRICTURE

    CPT 52270: Cystoscopy with Incision of Internal Urethral Stricture (Female)

    Showing 1–10 of 26

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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