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    v1.0.30
    OpenPayerBilling CodesExternally Accessible Renal Pelvis Catheter Introduction ProceduresCPT cpt-50389-nephrostomy-tube-removal-fluoroscopy-guided
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    CPT 50389: Nephrostomy Tube Removal with Fluoroscopic Guidance

    Medicare pays $414 on average nationally for this procedure.

    CPT code 50389 describes removal of a nephrostomy tube from the renal collecting system when no longer needed for urinary drainage; the procedure is performed with fluoroscopic guidance due to an indwelling ureteral stent or other reason, classifying it as an interventional radiology/urology procedure typically performed in an ambulatory surgical center, hospital outpatient department, or interventional radiology suite under local or monitored anesthesia care.

    For related coverage guidance, see recent payer policy updates: Vafseo (vadadustat) for anemia in CKD on dialysis, Metabolic Disorders - Cysteamine (Oral) Products for Individual and Family Plans, Kerendia (finerenone) — Coverage Criteria.

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    Clinical & Coding Specifications

    Clinical Context

    A 62-year-old male with a history of obstructive uropathy secondary to ureteral stricture underwent percutaneous nephrostomy tube placement for urinary drainage. After several weeks of therapy and confirmation of ureteral patency by antegrade nephrostogram under fluoroscopy, the interventional radiologist schedules removal of the nephrostomy tube. The procedure is performed in an outpatient interventional radiology suite or hospital radiology department using fluoroscopic guidance to confirm that no residual obstruction or leak exists and that an indwelling ureteral stent (if present) will maintain drainage. The patient is positioned, monitoring is applied, the existing catheter is prepped and connected for contrast injection to confirm free drainage into the bladder, and the catheter is removed over a guidewire or by simple traction when appropriate. Post-procedure instructions include observation for hematuria, flank pain, fever, and instruction for return precautions. Typical documentation includes site, laterality, indication, fluoroscopy use, contrast study findings, any complications, and disposition.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    50392Exchange of nephrostomy tube, percutaneous, including radiological supervision and interpretationPerformed when the existing nephrostomy tube is exchanged rather than removed
    50398Manipulation, repositioning, or removal of indwelling nephrostomy drain catheter, without imaging (list separately in addition to code for removal if applicable)`May be used when manipulation or simple bedside removal without fluoroscopy is performed; distinguishes non-fluoroscopic removals
    74450Urography, antegrade pyelography (percutaneous)Often performed immediately before removal to document collecting system patency and guide decision to remove
    50380Removal of percutaneous renal drainage catheter (non-fluoroscopic)Related when removal occurs without fluoroscopic guidance; differentiates technique and resource use
    76937Ultrasound guidance for percutaneous proceduresUsed when ultrasound guidance supplements or replaces fluoroscopy during nephrostomy tube management

    Related Modifiers

    10 rows

    ModifierDescriptionWhen to Use
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    54Modifier ‑54 (“Surgical care only”) is appended to a CPT surgical procedure when the reporting surgeon performs the intraoperative (surgical) component but does not furnish the preoperative and/or…- Use modifier -54 when the reporting surgeon provided only the intraoperative (surgical) component of a procedure and preoperative and/or postoperative management has been or will be provided by…
    55Modifier –55 indicates the billing provider furnished only postoperative management for a procedure that has a global surgical period. According to AAPC, this modifier is appended to the same CPT…- Use modifier -55 when billing the same CPT surgical code that has a 10- or 90-day global period and you, as a provider other than the original surgeon, furnished ONLY postoperative management (no…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    79Modifier 79 indicates a surgical procedure performed during the postoperative global period of a prior surgery that is unrelated to the original procedure. Per AMA/CPT and CMS guidance, it is…- Use modifier 79 when the same physician (or same‑specialty physician in the same group) performs a surgical procedure during the postoperative global period of a prior surgery and the new procedure…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    2080P0202X
    207R00000X
    363LN0005X
    2084P0800X
    2472D0500X
    1835P0018X
    2081P0010X
    1223X2210X

    Related Payer Policy Updates

    Specialty: Nephrology1 / 3

    10 rows

    PolicyPayerEffective Date
    Vafseo (vadadustat) for anemia in CKD on dialysisCigna2026-08-15
    Metabolic Disorders - Cysteamine (Oral) Products for Individual and Family PlansCigna2026-08-15
    Kerendia (finerenone) — Coverage CriteriaBlue Cross Blue Shield - Iowa2026-08-05
    Voyxact (sibeprenlimab-szsl) — Prior authorization / medical necessity for primary IgA nephropathyColorado Rocky Mountain Health Plans2026-08-01
    Oxlumo (lumasiran) and Rivfloza (nedosiran) — Coverage Criteria (Ohio)Colorado Rocky Mountain Health Plans2026-08-01
    Korsuva (difelikefalin) — Medical Benefit Drug Coverage Criteria (Ohio)Colorado Rocky Mountain Health Plans2026-08-01
    Complement Inhibitors - EmpaveliCigna2026-08-01
    Tolvaptan (Jynarque)Cigna2026-08-01
    Nephrology - Filspari (sparsentan) coverageCigna2026-08-01
    Rivfloza (nedosiran) prior authorization for PH1UnitedHealthcare2026-08-01

    Related Codes

    CPT-50387-NEPHROURETERAL-CATHETER-EXCHANGE-FLUOROSCOPY

    CPT 50387: Nephroureteral Catheter Removal and Replacement

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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