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    v1.0.30
    OpenPayerBilling CodesExternally Accessible Renal Pelvis Catheter Introduction ProceduresCPT cpt-50387-nephroureteral-catheter-exchange-fluoroscopy
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    CPT 50387: Nephroureteral Catheter Removal and Replacement

    Medicare pays $542 on average nationally for this procedure.

    CPT code 50387 describes fluoroscopically guided removal and replacement of an externally accessible nephroureteral stent/catheter connecting the renal pelvis and ureter to an external drainage system; the service includes radiological supervision and interpretation and is typically performed as an interventional radiology procedure in an outpatient interventional radiology suite or hospital interventional setting using live real‑time X‑ray imaging.

    For related coverage guidance, see recent payer policy updates: Vafseo (vadadustat) for anemia in CKD on dialysis, Metabolic Disorders - Cysteamine (Oral) Products for Individual and Family Plans, Kerendia (finerenone) — Coverage Criteria.

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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is an adult with an existing externally accessible nephroureteral stent/catheter placed for urinary drainage after ureteral obstruction from malignancy, ureteral injury, or complex stone disease. The patient presents to an interventional radiology suite or ambulatory surgery center for a scheduled exchange because the external catheter is malfunctioning, infected, displaced, or has reached routine exchange interval. Preprocedure evaluation includes review of indication, allergy and anticoagulation status, recent imaging confirming catheter position, and consent. On the day of service the patient is positioned on a fluoroscopy table, local anesthesia and conscious sedation are provided as indicated, and the interventional radiologist uses live fluoroscopic guidance to remove the existing nephroureteral catheter and place a replacement catheter with confirmation of appropriate renal pelvis and ureteral drainage. The service includes radiological supervision and interpretation of imaging and immediate postprocedural evaluation prior to discharge. Typical sites of service are the hospital interventional radiology suite, outpatient ambulatory surgery center, or hospital outpatient department when inpatient status is not required.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    50392Endoscopic placement of internal ureteral stent (eg, Gibbons or double-J type)May be performed as an alternative to external nephroureteral catheter placement or after resolution of obstruction to convert external drainage to internal stent.
    50390Nephrostomy, percutaneous, with or without injection for radiologic evaluation; initial placementOften performed when percutaneous renal drainage is initially required; nephroureteral catheter exchange may follow initial percutaneous access.
    50393Irrigation and/or manipulation of nephrostomy tube (except urography)Performed for maintenance or troubleshooting of external renal drainage catheters and may accompany exchange procedures.
    76937Ultrasound guidance for vascular access and/or for catheter placementMay be used adjunctively to localize renal access or guide initial trocar or wire placement during catheter exchange in some workflows.
    74240Urography, antegrade, pyelogram, radiological supervision and interpretation; including injection of contrast materialPerformed intra-procedurally to document collecting system anatomy and confirm catheter position during exchange.

    Related Modifiers

    9 rows

    ModifierDescriptionWhen to Use
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    79Modifier 79 indicates a surgical procedure performed during the postoperative global period of a prior surgery that is unrelated to the original procedure. Per AMA/CPT and CMS guidance, it is…- Use modifier 79 when the same physician (or same‑specialty physician in the same group) performs a surgical procedure during the postoperative global period of a prior surgery and the new procedure…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    363LP0200X
    207RH0002X
    208000000X
    207K00000X
    251300000X
    364SP1700X
    163WP2201X
    2080P1004X

    Related Payer Policy Updates

    Specialty: Nephrology1 / 3

    10 rows

    PolicyPayerEffective Date
    Vafseo (vadadustat) for anemia in CKD on dialysisCigna2026-08-15
    Metabolic Disorders - Cysteamine (Oral) Products for Individual and Family PlansCigna2026-08-15
    Kerendia (finerenone) — Coverage CriteriaBlue Cross Blue Shield - Iowa2026-08-05
    Voyxact (sibeprenlimab-szsl) — Prior authorization / medical necessity for primary IgA nephropathyColorado Rocky Mountain Health Plans2026-08-01
    Oxlumo (lumasiran) and Rivfloza (nedosiran) — Coverage Criteria (Ohio)Colorado Rocky Mountain Health Plans2026-08-01
    Korsuva (difelikefalin) — Medical Benefit Drug Coverage Criteria (Ohio)Colorado Rocky Mountain Health Plans2026-08-01
    Complement Inhibitors - EmpaveliCigna2026-08-01
    Tolvaptan (Jynarque)Cigna2026-08-01
    Nephrology - Filspari (sparsentan) coverageCigna2026-08-01
    Rivfloza (nedosiran) prior authorization for PH1UnitedHealthcare2026-08-01

    Related Codes

    CPT-50389-NEPHROSTOMY-TUBE-REMOVAL-FLUOROSCOPY-GUIDED

    CPT 50389: Nephrostomy Tube Removal with Fluoroscopic Guidance

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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