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    v1.0.30
    OpenPayerBilling CodesRepair Procedures on the RectumCPT cpt-45520-rectal-sclerotherapy-for-prolapsed-mucosa
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    CPT 45520: Sclerotherapy for Prolapsed Rectal Mucosa

    Medicare pays $176 on average nationally for this procedure.

    CPT code 45520 describes sclerotherapy, the injection of a chemical irritant (sclerosant) to treat prolapsed rectal mucosa; this is a minimally invasive anorectal procedure typically performed as an outpatient operative service in an office procedure room, ambulatory surgery center, or hospital outpatient setting to reduce symptomatic rectal prolapse or hemorrhoidal prolapse by inducing fibrosis and mucosal fixation.

    For related coverage guidance, see recent payer policy updates: Dental Anesthesia Services, Anesthesia Services for Interventional Pain Management Procedures in an Adult, General Anesthesia and Conscious Sedation Services.

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    Table of contents

    Progress1 / 7

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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is an adult presenting to a colorectal clinic with symptomatic internal hemorrhoids characterized by prolapsed mucosa causing bleeding, discomfort, and difficulty with hygiene. After history and physical exam including anoscopy or proctoscopy confirming prolapsed mucosal hemorrhoids suitable for non-surgical management, the provider discusses sclerotherapy as a minimally invasive office-based option. The procedure workflow: consent and pre-procedure vitals are obtained; the patient is positioned in left lateral or prone jackknife; anoscopic visualization identifies the target prolapsed mucosa; a sclerosant (chemical irritant) is injected into the submucosal tissue of the prolapsed hemorrhoidal cushions; hemostasis and post-injection inspection are performed; recovery includes brief observation, discharge instructions for analgesia and bowel regimen, and follow-up. Typical site of service is an outpatient office or ambulatory surgical center. The service type is a minor therapeutic procedure (sclerotherapy) directed at prolapsed rectal mucosa for hemorrhoidal disease.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    46945Hemorrhoidectomy, internal and external; simple (e.g., closed, with or without sphincterotomy)Surgical excision alternative when sclerotherapy is ineffective or for advanced disease
    46946Hemorrhoidectomy, internal and external; extensive (e.g., with blood vessel ligation)More extensive surgical treatment for severe or recurrent prolapsed hemorrhoids
    46030Anoscopy, diagnostic, with or without collection of specimen(s) by brushing or washing (separate procedure)Diagnostic anoscopy performed before sclerotherapy to identify target tissue
    46221Flexible sigmoidoscopy, diagnostic, limited, with or without collection of specimen(s) by brushing or washingPerformed when evaluation of distal colon is indicated in conjunction with anorectal complaints
    46999Unlisted procedure, anus, rectum and perirectal tissueUsed for atypical anorectal procedures not described by specific codes when sclerotherapy technique is novel or combined with other unlisted maneuvers

    Related Modifiers

    13 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    54Modifier ‑54 (“Surgical care only”) is appended to a CPT surgical procedure when the reporting surgeon performs the intraoperative (surgical) component but does not furnish the preoperative and/or…- Use modifier -54 when the reporting surgeon provided only the intraoperative (surgical) component of a procedure and preoperative and/or postoperative management has been or will be provided by…
    55Modifier –55 indicates the billing provider furnished only postoperative management for a procedure that has a global surgical period. According to AAPC, this modifier is appended to the same CPT…- Use modifier -55 when billing the same CPT surgical code that has a 10- or 90-day global period and you, as a provider other than the original surgeon, furnished ONLY postoperative management (no…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    66Modifier 66 (Surgical Team) is used when three or more surgeons act as primary surgeons on a single, highly complex procedure. The AMA defines it for use when a surgical team — often composed of…- Use modifier 66 when three or more surgeons act as primary surgeons working collaboratively as a surgical team on a single, highly complex or difficult procedure (for example organ…

    Showing 1–10 of 13

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207RH0000X
    207L00000X
    207K00000X
    208D00000X
    363LN0005X
    225XP0200X
    246XC2903X
    3416S0300X

    Related ICD-10-CM Codes

    23 rows

    ICD-10-CM CodeDescription
    E66.9Obesity, unspecified
    F41.9Anxiety disorder, unspecified
    K52.9Noninfective gastroenteritis and colitis, unspecified
    K57.32Diverticulitis of large intestine without perforation or abscess without bleeding
    K58.9Irritable bowel syndrome, unspecified
    K59.1Functional diarrhea
    K62.3Rectal prolapse
    K62.4Stenosis of anus and rectum
    K62.5Hemorrhage of anus and rectum
    K62.6Ulcer of anus and rectum

    Showing 1–10 of 23

    Related Payer Policy Updates

    Specialty: Anesthesiology1 / 3

    10 rows

    PolicyPayerEffective Date
    Dental Anesthesia ServicesProvidence Health Plan2026-10-01
    Anesthesia Services for Interventional Pain Management Procedures in an AdultCigna2026-09-15
    General Anesthesia and Conscious Sedation ServicesUnitedHealthcare2026-09-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Elective Inpatient Services (for Idaho Only)UnitedHealthcare2026-06-01
    Sites of Servicepriority health2026-06-01
    Coverage for Ambulatory Surgery Unit (ASU)/Outpatient Facility and Anesthesia for Dental Servicesuniverahealthcare2026-05-21

    Related Codes

    CPT-45500-ANORECTAL-STENOSIS-RELEASE-WITH-FLAP-REPAIR

    CPT 45500: Surgical Release of Anorectal Stenosis with Flap Repair

    CPT-45505-RECTAL-MUCOSA-EXCISION-AND-FLAP-REPAIR

    CPT 45505: Excision of Prolapsed Rectal Mucosa with Flap Repair

    CPT-45540-ABDOMINAL-RECTOPEXY-RECTAL-PROLAPSE-MESH-SUTURE

    CPT 45540: Abdominal Repair of Rectal Prolapse with Suture and Mesh

    CPT-45541-PERINEAL-RECTAL-PROLAPSE-REPAIR-MESH-SUTURES

    CPT 45541: Perineal Repair of Rectal Prolapse with Sutures and Mesh

    CPT-45550-RECTOPEXY-WITH-SIGMOID-RESECTION

    CPT 45550: Abdominal Repair of Rectal Prolapse with Sigmoid Resection

    CPT-45560-RECTOCELE-REPAIR-VAGINAL

    CPT 45560: Rectocele Repair, Vaginal

    CPT-45562-RECTAL-REPAIR-PRESACRAL-DRAINAGE

    CPT 45562: Exploration and Repair of Rectum with Presacral Drainage

    CPT-45563-RECTAL-INJURY-REPAIR-SIGMOID-COLOSTOMY

    CPT 45563: Exploratory Abdominal Surgery, Repair Rectal Injury and Sigmoid Colostomy

    CPT-45800-RECTOVESICAL-FISTULA-REPAIR-OPEN-ABDOMINAL

    CPT 45800: Repair of Rectovesical Fistula, Abdominal Approach

    CPT-45805-RECTOVESICAL-FISTULA-REPAIR-WITH-SIGMOID-COLOSTOMY

    CPT 45805: Rectovesical Fistula Repair with Sigmoid Colostomy

    Showing 1–10 of 12

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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