CPT code 45382 designates a colonoscopic procedure performed to identify and control sources of lower gastrointestinal bleeding. It combines diagnostic visualization of the colon and rectum using a colonoscope with therapeutic interventions to achieve hemostasis. Nationally, this code is important because gastrointestinal bleeding is a common acute presentation that often requires timely endoscopic management to reduce morbidity, avoid transfusion, and shorten hospital stays.

Key payers covered in this analysis include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find a concise explanation of the clinical context for the code, typical sites where the service is delivered (ambulatory surgical centers and hospital endoscopy suites), and what to expect in payer coverage discussions. The publication also summarizes common billing considerations, typical modifiers used with endoscopic therapeutic procedures, and related claims-processing and documentation themes.

The content provides benchmarks and policy-relevant updates useful for coding professionals, revenue cycle teams, and clinical leaders: when CPT code 45382 applies, how it aligns with procedural intent (diagnosis plus hemostasis), and the practical settings in which the service is performed. Data not available in the input is noted where applicable.