CPT code 45110 represents an abdominoperineal resection with colostomy, a major surgical procedure that removes the rectum, part of the lower colon, and the anal sphincter, and creates a permanent colostomy. This operation is most often used for distal rectal cancers or severe Crohn colitis when the diseased segment cannot be managed via a transanal approach. Nationally, this code captures high-acuity colorectal surgical care with implications for hospital resource use, perioperative quality measures, and long-term patient management.

Key payers covered in this analysis include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find an overview of the clinical context for the procedure, the typical inpatient surgical setting where the service is delivered, and the common payer coverage landscape. The publication outlines benchmarking considerations, coding and billing context, and policy-relevant items such as documentation elements that support medical necessity for a major abdominoperineal resection. It also summarizes typical service lines and what to expect for coding workflows and recordkeeping. Data not available in the input is noted where applicable.