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    v1.0.30
    OpenPayerBilling CodesEnterostomy-External Fistulization of Intestines ProceduresCPT cpt-44322-colostomy-or-cecostomy-stoma-creation-with-biopsy
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    CPT 44322: Colostomy Creation with Intestinal Biopsy

    Medicare pays $1000 on average nationally for this procedure.

    CPT code 44322 describes a surgical colostomy creation with local intestinal biopsy, in which the surgeon brings a loop of colon or cecum to the abdominal wall, opens that segment and sutures it to the skin to provide direct access for bowel emptying while obtaining multiple biopsy specimens; service type: surgical open bowel procedure, typical site of service: operating room or inpatient surgical suite.

    For related coverage guidance, see recent payer policy updates: Percutaneous Electrical Nerve Field Stimulation for Functional Abdominal Pain Disorders, Esophagogastroduodenoscopy (EGD) Coverage Policy, Radiofrequency Therapy for Fecal Incontinence.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 64-year-old patient with chronic refractory colonic inertia and recurrent fecal impaction is scheduled for creation of a temporary or permanent colostomy for bowel decompression and access. The patient has failed conservative therapies including laxatives and enemas, and continues to have obstructive symptoms with proximal colonic dilatation on imaging. Under general anesthesia in an operating room or ambulatory surgical center, the surgeon mobilizes a segment of the sigmoid colon (or cecum/right colon if indicated), brings a loop of bowel through a planned abdominal wall incision, opens the bowel lumen, and matures the bowel edges to the skin to create a stoma. During the same operative session, the surgeon obtains multiple mucosal biopsy specimens along the pulled-through segment to evaluate for inflammatory, ischemic, or neuropathic pathology. Intraoperative steps include bowel selection and mobilization, spawning a stoma tract, mucosal incision, biopsy sampling, and maturation of the bowel to the abdominal wall. Typical perioperative workflow includes pre-op consent and bowel prep as indicated, general anesthesia, surgical procedure in the OR or ASC, immediate stoma care teaching, and post-anesthesia recovery with short inpatient stay or same-day discharge depending on comorbidity and complexity.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    44320Colostomy; creation, mucous fistula, or loop colostomyClosely related procedure; 44322 is specific for loop colostomy with biopsy sampling along the intestinal segment.
    44140Colectomy, partial; single resection and anastomosisPerformed when definitive resection is indicated instead of a diversion; may be done before or after diversion in staged care.
    44325Closure of temporary colostomyPerformed when reversal of the stoma created with 44322 is planned.
    88305Surgical pathology, gross and microscopic examinationUsed for processing and interpretation of biopsy specimens obtained during the procedure.
    43239Upper GI endoscopy with biopsy, single or multipleNot directly performed together in the OR, but endoscopic biopsy CPTs represent similar pathology sampling and processing workflows; may be used for preoperative evaluation.

    Related Modifiers

    12 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    63Modifier‑63 is appended to surgical CPT codes (20000–69990) when a procedure is performed on a neonate or infant weighing ≤ 4 kg (about 8.8 lbs). The AMA/AAPC definition specifies this use and notes…- Use modifier -63 only for surgical procedures in the CPT 20000–69990 series performed on a neonate or infant who weighs ≤ 4 kg at the time of the procedure; it indicates increased complexity due to…
    66Modifier 66 (Surgical Team) is used when three or more surgeons act as primary surgeons on a single, highly complex procedure. The AMA defines it for use when a surgical team — often composed of…- Use modifier 66 when three or more surgeons act as primary surgeons working collaboratively as a surgical team on a single, highly complex or difficult procedure (for example organ…

    Showing 1–10 of 12

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207L00000X
    363LP2300X
    207RH0000X
    2080P0208X
    111NP0017X
    207T00000X
    344600000X
    207RT0003X

    Related ICD-10-CM Codes

    26 rows

    ICD-10-CM CodeDescription
    C18.9Malignant neoplasm of colon, unspecified
    C19Malignant neoplasm of rectosigmoid junction
    C20Malignant neoplasm of rectum
    K50.90Crohn's disease, unspecified, without complications
    K52.9Noninfective gastroenteritis and colitis, unspecified
    K57.10Diverticulosis of small intestine without perforation or abscess without bleeding
    K57.12Diverticulitis of small intestine without perforation or abscess without bleeding
    K57.20Diverticulitis of large intestine with perforation and abscess without bleeding
    K57.30Diverticulosis of large intestine without perforation or abscess without bleeding
    K57.32Diverticulitis of large intestine without perforation or abscess without bleeding

    Showing 1–10 of 26

    Related Payer Policy Updates

    Specialty: Gastroenterology1 / 4

    10 rows

    PolicyPayerEffective Date
    Percutaneous Electrical Nerve Field Stimulation for Functional Abdominal Pain Disordersbcbsvermont2026-12-01
    Esophagogastroduodenoscopy (EGD) Coverage Policyevicore2026-11-05
    Radiofrequency Therapy for Fecal IncontinenceCigna2026-10-15
    Magnetic Sphincter Augmentation for the Treatment of Gastroesophageal Reflux Disease (GERD)univerahealthcare2026-10-15
    High-Resolution Anoscopy (HRA)Premera Bluecross2026-10-01
    Gastroesophageal and Gastrointestinal (GI) Services and ProceduresColorado Rocky Mountain Health Plans2026-10-01
    Fecal Analysis in the Diagnosis of Intestinal Dysbiosis and Fecal Microbiota Transplant TestingOscar Health2026-10-01
    Serum Testing for Hepatic Fibrosis in the Evaluation and Monitoring of Chronic Liver DiseaseOscar Health2026-10-01
    Pancreatic Enzyme Testing for Acute PancreatitisOscar Health2026-10-01
    Helicobacter pylori TestingOscar Health2026-10-01

    Related Codes

    CPT-44300-OPEN-ENTEROSTOMY-FEEDING-TUBE-PLACEMENT

    CPT 44300: Open Enterostomy or Cecostomy Tube Placement

    CPT-44310-SMALL-INTESTINE-ENTEROSTOMY-LOOP-ILEUM-JEJUNUM

    CPT 44310: Ileostomy or Jejunostomy (Small Bowel Stoma)

    CPT-44312-STOMAL-ADHESIOLYSIS-RELEASE-ILEOSTOMY-STOMA

    CPT 44312: Release of Scar Tissue Around Ileostomy Stoma

    CPT-44314-ILEOSTOMY-STOMA-REVISION

    CPT 44314: Revision of Ileal Stoma (Stoma Relocation)

    CPT-44316-CREATION-OF-ILEAL-POUCH-STOMA

    CPT 44316: Creation of Abdominal Ileostomy Connected to Ileal Pouch

    CPT-44320-COLOSTOMY-CECOSTOMY-STOMA-CREATION

    CPT 44320: Colostomy/Stoma Formation, Loop Colostomy

    CPT-44340-STOMA-ADHESIOLYSIS-RELEASE-OF-PERISTOMAL-SCAR

    CPT 44340: Stoma Adhesiolysis (Release of Scar Tissue Around Colon Stoma)

    CPT-44345-COLOSTOMY-STOMA-RELOCATION-REVISION

    CPT 44345: Stomal Revision and Repositioning of Colon

    CPT-44346-COLOSTOMY-STOMA-REVISION

    CPT 44346: Colostomy (Stoma) Revision

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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