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    OpenPayerBilling CodesIncision Procedures on the Salivary Gland and DuctsCPT cpt-42330-sialolithotomy-removal-salivary-gland-stone
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    CPT 42330: Sialolithotomy, Removal of Salivary Gland Stone

    Medicare pays $246 on average nationally for this procedure.

    CPT code 42330 describes a sialolithotomy, the surgical removal of a salivary gland stone (sialolith) from glands such as the submandibular, sublingual, or parotid; the service is a minor surgical procedure typically performed in an ambulatory surgery center, hospital outpatient department, or office-based surgical suite for relief of obstructive salivary gland symptoms and restoration of salivary flow.

    For related coverage guidance, see recent payer policy updates: Orthopedic Joint Procedures of the Knee for Managed Medicaid (MMC), Health and Recovery Plan (HARP), Child Health Plus (CHP), and Essential Plan (EP) Members, Autologous Chondrocyte Transplantation or Implantation Corporate Medical Policy, Autologous Platelet-Derived Growth Factors (Platelet-Rich Plasma [PRP]).

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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is an adult presenting to an otolaryngology clinic with acute unilateral submandibular swelling, intermittent pain and increased swelling at mealtimes, and possible low-grade fever. Examination and ultrasound confirm a sialolith obstructing the submandibular duct (Wharton's duct). Conservative measures such as hydration, sialogogues, and massage were attempted; symptoms persisted or the stone is large/firm and located within the gland or duct. The patient is scheduled for 42330 (sialolithotomy) performed under local or general anesthesia in an outpatient ambulatory surgery center or hospital operating room. The clinical workflow includes preoperative imaging review (ultrasound or CT), informed consent, anesthesia evaluation, intraoperative localization and incision of the duct, removal of the calculus, ductal repair or stenting if needed, hemostasis, and postoperative instructions with short-term antibiotics or analgesics as indicated. Typical site of service is the oral cavity/upper aerodigestive tract with providers commonly being otolaryngologists (ENT) or oral and maxillofacial surgeons.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    41899Unlisted procedure, dentoalveolar structuresUsed when an unusual or atypical salivary duct procedure is performed that does not fit existing codes; submitted with operative report.
    42800Excision or destruction of lesion of floor of mouth or tongue baseMay be performed if concurrent pathology in the floor of mouth requires excision during sialolithotomy.
    42440Excision of submandibular glandPerformed when chronic sialadenitis or recurrent stones require definitive gland removal instead of 42330.
    76942Ultrasonic guidance for needle placement (e.g., biopsy, aspiration)Used preoperatively for localization or intraoperative ultrasound-guided stone localization.
    99152Moderate sedation services provided by the same physician performing the procedure (initial 15 minutes)Billed if physician provides monitored anesthesia care or moderate sedation during 42330 (follow facility and payer rules).

    Related Modifiers

    12 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    25CPT modifier 25 indicates that on the same day as another procedure or service, the same physician or other qualified health care professional provided a significant, separately identifiable…- When to apply: Use modifier 25 only on an E/M code to indicate the same provider delivered a significant, separately identifiable E/M service on the same day as another procedure or service — i.e.,…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    66Modifier 66 (Surgical Team) is used when three or more surgeons act as primary surgeons on a single, highly complex procedure. The AMA defines it for use when a surgical team — often composed of…- Use modifier 66 when three or more surgeons act as primary surgeons working collaboratively as a surgical team on a single, highly complex or difficult procedure (for example organ…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
    77Modifier 77 indicates that a previously performed procedure or service was legitimately repeated by a different physician or other qualified health care professional. The AMA’s CPT definition…- Use modifier 77 when a basic procedure or service already performed is repeated by a different physician or other qualified health care professional (for example, a second provider independently…

    Showing 1–10 of 12

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207Y00000X
    2084P0800X
    163WC0200X
    207RI0001X
    225000000X
    207Q00000X
    261QE0002X
    213ES0103X

    Related Payer Policy Updates

    Specialty: Orthopedics/Musculoskeletal1 / 3

    10 rows

    PolicyPayerEffective Date
    Orthopedic Joint Procedures of the Knee for Managed Medicaid (MMC), Health and Recovery Plan (HARP), Child Health Plus (CHP), and Essential Plan (EP) Membersuniverahealthcare2027-01-01
    Autologous Chondrocyte Transplantation or Implantation Corporate Medical Policybcbsvermont2026-12-01
    Autologous Platelet-Derived Growth Factors (Platelet-Rich Plasma [PRP])Cigna2026-10-15
    Metatarsophalangeal Joint ReplacementCigna2026-10-15
    Shoulder Arthroplasty (Total, Partial, Reverse, Revision and Resurfacing)univerahealthcare2026-10-15
    Hip Arthroplasty (partial and total hip replacement)univerahealthcare2026-10-15
    Artificial Lumbar Intervertebral Disc (Lumbar Total Disc Arthroplasty)univerahealthcare2026-10-15
    Osteochondral Grafting of the Kneeuniverahealthcare2026-10-15
    Lumbar Fusion (arthrodesis) with decompressionuniverahealthcare2026-10-15
    Metal-on-Metal Total Hip Resurfacinguniverahealthcare2026-10-15

    Related Codes

    CPT-42300-PAROTID-ABSCESS-DRAINAGE

    CPT 42300: Drainage of Parotid Salivary Gland Abscess

    CPT-42305-PAROTID-ABSCESS-DRAINAGE-COMPLEX

    CPT 42305: Complex Drainage of Parotid Gland Abscess

    CPT-42310-INCISION-DRAINAGE-SUBMANDIBULAR-SUBLINGUAL-ABSCESS

    CPT 42310: Incision and Drainage of Submaxillary or Sublingual Salivary Gland Abscess

    CPT-42320-SUBMAXILLARY-SALIVARY-GLAND-ABSCESS-DRAINAGE-EXTERNAL-APPROACH

    CPT 42320: External Drainage of Submaxillary Salivary Gland

    CPT-42335-SIALOLITHOTOMY-SALIVARY-GLAND-STONE-REMOVAL

    CPT 42335: Sialolithotomy, Removal of Salivary Stone

    CPT-42340-SIALOLITHOTOMY-PAROTID-GLAND-REMOVAL

    CPT 42340: Sialolithotomy, Parotid Gland

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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