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    OpenPayerBilling CodesExcision and Destruction Procedures on the Vestibule of MouthCPT cpt-40810-excision-oral-mucosa-submucosa-lesion
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    CPT 40810: Excision of Lesion of Anterior Oral Mucosa and Submucosa

    Medicare pays $224 on average nationally for this procedure.

    CPT code 40810 describes excision of a lesion or area of damaged or diseased oral mucosa and the underlying submucosa, a surgical procedure performed in an operative or ambulatory surgical setting that does not include repair of the surgical wound; this procedure represents an excisional mucosal/submucosal removal in the anterior oral cavity and is coded for documentation and billing of that specific surgical service.

    For related coverage guidance, see recent payer policy updates: Orthognathic Surgery, Temporomandibular Disorders - Nonsurgical Treatment, Temporomandibular Disorders.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 45-year-old patient presents to an outpatient oral surgery clinic with a symptomatic 6 mm ulcerated lesion of the anterior oral mucosa on the inner lower lip that has failed conservative therapy. The oral and maxillofacial surgeon reviews history, performs an intraoral exam and documents size, location, and clinical suspicion for dysplasia or localized infection. After informed consent, the patient is prepared in a procedure room. Local anesthesia is administered, and the surgeon excises the lesion including the mucosa and submucosa down to, but not including, deeper muscle or skin layers. Hemostasis is achieved with cautery and simple packing; no layered closure or complex reconstruction is performed. The excised specimen is sent for pathology. Postoperative instructions and analgesics are provided, and a short follow-up visit is arranged.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    11100Biopsy of single skin, subcutaneous and/or mucous membrane lesion; single lesionPerformed when a diagnostic biopsy (shave/punch) is chosen instead of or prior to full excision.
    40490Excision of lesion of lip; 1.5 cm or less, simple repairUsed when an excision includes deeper tissues and a simple repair is performed; may be considered for lip lesions involving vermilion or skin.
    41820Excision of benign lesion of oral mucosa, complicated, requiring layered closurePerformed when excision requires more extensive dissection and layered closure beyond mucosa/submucosa.
    99024Postoperative follow-up visit, routine, after surgeryUsed for routine postoperative visits associated with surgical care (payer-dependent reporting).
    88305Level IV surgical pathology, gross and microscopic examinationTypically reported by the pathology lab for the specimen sent after excision.

    Related Modifiers

    11 rows

    ModifierDescriptionWhen to Use
    25CPT modifier 25 indicates that on the same day as another procedure or service, the same physician or other qualified health care professional provided a significant, separately identifiable…- When to apply: Use modifier 25 only on an E/M code to indicate the same provider delivered a significant, separately identifiable E/M service on the same day as another procedure or service — i.e.,…
    57CPT® modifier -57 (“Decision for Surgery”) is appended to an Evaluation and Management (E/M) service when that encounter results in the initial decision to perform a major surgery (a procedure with a…- Use modifier 57 when an E/M service provided by the same provider (or same tax ID) on the day of or the day before a major surgical procedure (90‑day global period) results in the initial decision…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    54Modifier ‑54 (“Surgical care only”) is appended to a CPT surgical procedure when the reporting surgeon performs the intraoperative (surgical) component but does not furnish the preoperative and/or…- Use modifier -54 when the reporting surgeon provided only the intraoperative (surgical) component of a procedure and preoperative and/or postoperative management has been or will be provided by…
    55Modifier –55 indicates the billing provider furnished only postoperative management for a procedure that has a global surgical period. According to AAPC, this modifier is appended to the same CPT…- Use modifier -55 when billing the same CPT surgical code that has a 10- or 90-day global period and you, as a provider other than the original surgeon, furnished ONLY postoperative management (no…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…

    Showing 1–10 of 11

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207L00000X
    207X00000X
    207RH0000X
    235500000X
    281PC2000X
    2083S0010X
    101200000X
    207XP3100X

    Related Payer Policy Updates

    Specialty: Dental/Oral & Maxillofacial1 / 2

    10 rows

    PolicyPayerEffective Date
    Orthognathic SurgeryCigna2026-10-15
    Temporomandibular Disorders - Nonsurgical TreatmentCareSource Georgia2026-10-01
    Temporomandibular DisordersAnthem2026-10-01
    Treatment of Temporomandibular Joint DisordersUnitedHealthcare2026-10-01
    IV Moderate Sedation, IV Deep Sedation, and General Anesthesia for Dental ProceduresAmbetter Georgia2026-10-01
    Orthognathic SurgeryPremera Bluecross2026-09-04
    Orthognathic SurgeryPremera Bluecross2026-09-04
    9.02.501 Orthognathic SurgeryPremera Bluecross2026-09-04
    Oral Surgery: Orthodontic Related ProceduresUnitedHealthcare2026-09-01
    Orthognathic SurgeryProvidence Health Plan2026-09-01

    Related Codes

    CPT-40808-ORAL-VESTIBULE-BIOPSY

    CPT 40808: Biopsy, Excision of Vestibule of Mouth

    CPT-40812-ORAL-MUCOSA-SUBMUCOSA-LESION-EXCISION-SIMPLE-REPAIR

    CPT 40812: Excision of Anterior Oral Mucosa and Submucosa, Simple Repair

    CPT-40814-ORAL-MUCOSA-SUBMUCOSA-EXCISION-COMPLEX-REPAIR

    CPT 40814: Excision of Mucosa and Submucosa with Complex Repair

    CPT-40816-ORAL-MUCOSA-SUBMUCOSA-MUSCLE-EXCISION

    CPT 40816: Excision of Mucosa, Submucosa, and Underlying Muscle of Oral Vestibule

    CPT-40818-ORAL-MUCOSAL-GRAFT-HARVEST

    CPT 40818: Oral Vestibular Mucosal Graft Harvest

    CPT-40819-FRENULECTOMY-LABIAL-BUCCAL

    CPT 40819: Labial or Buccal Frenectomy

    CPT-40820-ORAL-VESTIBULE-LESION-ERADICATION-NONEXCISIONAL

    CPT 40820: Destruction of Lesion in Oral Vestibule

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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