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    OpenPayerBilling CodesExcision Procedures on the Spine (Vertebral Column)CPT cpt-22110-cervical-vertebral-body-excision-single-level
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    CPT 22110: Excision of Portions of Cervical Vertebral Body

    Medicare pays $1031 on average nationally for this procedure.

    CPT code 22110 describes excision of portions of the main body of a single cervical vertebra to remove a damaged or diseased area within that one bone; this procedure is a partial vertebral body excision performed by a surgeon as an operative (surgical) procedure typically in an inpatient or outpatient hospital operating room or ambulatory surgery center when focused bone resection is required without decompression of the spinal cord or nerve roots.

    For related coverage guidance, see recent payer policy updates: Clinical Review Criteria Intraoperative Neurophysiological Monitoring (IONM), Remote Electrical Neuromodulation for Migraines (i.e., Nerivio®), Lumbar Microdiscectomy.

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    Clinical & Coding Specifications

    Clinical Context

    A patient in their mid-50s presents with a focal destructive lesion confined to the body of a single cervical vertebra, identified on cervical spine CT and MRI. The patient reports progressive neck pain and localized tenderness at the corresponding level; there is no objective myelopathy or radiculopathy on neurologic exam and imaging shows the spinal canal and neural foramina are preserved without cord or nerve root compression. Conservative measures including analgesics and activity modification have failed. The surgical team (orthopaedic spine surgeon or neurosurgeon) schedules an operative excision of the diseased portion of the vertebral body under general anesthesia. The procedure involves a focused resection of the affected vertebral body segment to remove tumor, infection, or osteonecrotic bone while intentionally avoiding decompression of the spinal cord or nerve roots. Typical workflow includes preoperative imaging review, anesthesia evaluation, intraoperative fluoroscopic localization, lesion excision with hemostasis, possible structural grafting or reconstruction if stability is affected, and routine postoperative recovery in the PACU with follow-up imaging to confirm lesion removal and spinal stability. Typical site of service is an inpatient or outpatient hospital operating room depending on complexity; ambulatory surgery center use is uncommon when reconstruction or monitoring is anticipated.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    20610Arthrocentesis, aspiration and/or injection; major joint or bursa (e.g., shoulder, hip)May be used diagnostically or therapeutically preoperatively for differential diagnosis of neck/shoulder pain, though not directly related to vertebral body excision.
    22630Arthrodesis, posterior or posterolateral technique, single level; lumbarRepresents fusion procedures that may be performed if vertebral body excision compromises stability and posterior fusion is required; provides structural stabilization following resection.
    22845Anterior instrumentation; 2 to 3 vertebral segmentsUsed when anterior spinal instrumentation is required for reconstruction after excision of a cervical vertebral body portion to restore stability.
    20930Allograft, morselized, or placement of osteoconductive materialMay be used to fill a defect in the vertebral body after excision when structural grafting or augmentation is performed.
    22851Application of intervertebral biomechanical device(s) (e.g., spacers) with posterior instrumentationPerformed when segmental reconstruction of the cervical spine is needed in conjunction with excision to maintain alignment and stability.

    Related Modifiers

    9 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    63Modifier‑63 is appended to surgical CPT codes (20000–69990) when a procedure is performed on a neonate or infant weighing ≤ 4 kg (about 8.8 lbs). The AMA/AAPC definition specifies this use and notes…- Use modifier -63 only for surgical procedures in the CPT 20000–69990 series performed on a neonate or infant who weighs ≤ 4 kg at the time of the procedure; it indicates increased complexity due to…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    79Modifier 79 indicates a surgical procedure performed during the postoperative global period of a prior surgery that is unrelated to the original procedure. Per AMA/CPT and CMS guidance, it is…- Use modifier 79 when the same physician (or same‑specialty physician in the same group) performs a surgical procedure during the postoperative global period of a prior surgery and the new procedure…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    2084P0800X
    207L00000X
    111NN0400X
    163WH0200X
    2085U0001X
    221700000X
    2080P0008X
    261QR1100X

    Related Payer Policy Updates

    Specialty: Neurology/Neurosurgery1 / 3

    10 rows

    PolicyPayerEffective Date
    Clinical Review Criteria Intraoperative Neurophysiological Monitoring (IONM)Kaiser Permanente2027-01-01
    Remote Electrical Neuromodulation for Migraines (i.e., Nerivio®)bcbsvermont2026-11-01
    Lumbar Microdiscectomyuniverahealthcare2026-10-15
    Artificial Cervical Intervertebral Discuniverahealthcare2026-10-15
    Lumbar Decompressionuniverahealthcare2026-10-15
    Responsive Neurostimulation for Focal EpilepsyPremera Bluecross2026-10-14
    Intraoperative MonitoringProvidence Health Plan2026-10-01
    Intraoperative MonitoringProvidence Health Plan2026-10-01
    High-Intensity Focused UltrasoundMass General Brigham Health Plan2026-10-01
    Vagal Nerve StimulationAmbetter Nevada2026-10-01

    Related Codes

    CPT-22100-CERVICAL-VERTEBRAL-POSTERIOR-EXCISION-BONY-LESION

    CPT 22100: Partial Excision of Posterior Cervical Vertebra for Bony Lesion

    CPT-22101-THORACIC-VERTEBRAL-POSTERIOR-EXCISION-BONY-LESION

    CPT 22101: Excision of Posterior Thoracic Vertebral Bony Lesion

    CPT-22102-LUMBAR-VERTEBRAL-BONY-LESION-EXCISION

    CPT 22102: Excision of Lumbar Vertebral Bony Lesion

    CPT-22103-EXCISION-POSTERIOR-VERTEBRAL-BONY-LESION

    CPT 22103: Excision of Posterior Vertebral Element for Bony Lesion

    CPT-22112-THORACIC-VERTEBRAL-BODY-RESECTION

    CPT 22112: Excision of Thoracic Vertebral Body, Single Level

    CPT-22114-LUMBAR-VERTEBRAL-BODY-EXCISION

    CPT 22114: Excision of Portions of a Single Lumbar Vertebral Body

    CPT-22116-VERTEBRAL-BODY-EXCISION-SINGLE-VERTEBRA

    CPT 22116: Vertebral Body Excision, Single Vertebra

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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