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    v1.0.30
    OpenPayerBilling CodesExcision Procedures on the Spine (Vertebral Column)CPT cpt-22101-thoracic-vertebral-posterior-excision-bony-lesion
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    CPT 22101: Excision of Posterior Thoracic Vertebral Bony Lesion

    Medicare pays $880 on average nationally for this procedure.

    CPT code 22101 describes excision of the posterior elements (lamina or back part) of a single thoracic vertebra to remove a bony lesion contained within that vertebral body; this is a surgical excision of a thoracic vertebral lesion typically performed as an open spine procedure in an operating room or inpatient surgical setting to achieve lesion removal and decompression of adjacent neural elements when indicated.

    For related coverage guidance, see recent payer policy updates: Clinical Review Criteria Intraoperative Neurophysiological Monitoring (IONM), Remote Electrical Neuromodulation for Migraines (i.e., Nerivio®), Lumbar Microdiscectomy.

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    Table of contents

    Progress1 / 7

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    Clinical & Coding Specifications

    Clinical Context

    A 58-year-old patient presents with progressive localized thoracic back pain, focal tenderness, and imaging revealing an isolated lytic bony lesion within the posterior element of a single thoracic vertebra. Neurologic exam is non-focal, and CT/MRI demonstrates a contained lesion limited to the spinous process/lamina without gross epidural extension. The surgical plan is a posterior approach excision of the bony lesion via partial removal of the posterior element of the involved thoracic vertebra to obtain diagnostic tissue and achieve local control.

    Preoperative workflow includes history and physical, imaging review (CT and MRI), informed consent, anesthesia evaluation, and perioperative antibiotics. Intraoperatively, the patient is positioned prone, a midline posterior incision is made, subperiosteal dissection exposes the lamina and spinous process, and the surgeon excises the bony lesion (partial hemilaminectomy or laminotomy as required) with preservation of spinal stability when possible. Specimens are sent for pathology. Postoperative workflow includes recovery in PACU, pain control, wound monitoring, activity restrictions, and pathology follow-up to guide further oncologic or infectious management if indicated.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    20220Biopsy, bone, deep, includes obtaining specimen(s) by percutaneous or open approach, single or multiple, with image guidance when performedUsed when preoperative biopsy of the vertebral lesion is performed percutaneously prior to definitive excision.
    22102Excision, posterior or posterolateral element, single vertebra, thoracic; hemilaminectomy, partial facetectomy and/or excision of tumor involving posterior elements, more extensive than code 22101Performed when the lesion requires a more extensive resection than described by 22101.
    22830Exploration of spinal fusion, removal of instrumentation (removal of posterior non-segmental instrumentation)Performed if prior posterior hardware requires removal to access the lesion.
    69990Microsurgical techniques, intraoperative, requiring use of an operating microscope (list separately in addition to code for primary procedure)Reported when microsurgical magnification is used during excision to preserve neural elements.
    20900Bone graft, major or minor, any method, any donor area; major or minor, includes obtaining graftReported if local bone grafting or reconstruction is performed after excision to restore structural integrity.

    Related Modifiers

    12 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    63Modifier‑63 is appended to surgical CPT codes (20000–69990) when a procedure is performed on a neonate or infant weighing ≤ 4 kg (about 8.8 lbs). The AMA/AAPC definition specifies this use and notes…- Use modifier -63 only for surgical procedures in the CPT 20000–69990 series performed on a neonate or infant who weighs ≤ 4 kg at the time of the procedure; it indicates increased complexity due to…
    73Modifier 73 indicates a facility-level outpatient hospital or ASC procedure that was discontinued after the patient was prepared and taken to the procedure/operating room but before any anesthesia…- When to use: Apply CPT modifier 73 on the FACILITY (outpatient hospital or ASC) claim when the patient has been fully prepared and physically taken into the procedure/operating room but the…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…

    Showing 1–10 of 12

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207L00000X
    207RP1001X
    332H00000X
    208U00000X
    2279P1005X
    261QB0400X
    2279E1000X
    2472R0900X

    Related ICD-10-CM Codes

    23 rows

    ICD-10-CM CodeDescription
    C41.2Malignant neoplasm of vertebral column
    C79.31Secondary malignant neoplasm of brain
    C79.51Secondary malignant neoplasm of bone
    G95.9Disease of spinal cord, unspecified
    M43.16Spondylolisthesis, lumbar region
    M43.17Spondylolisthesis, lumbosacral region
    M47.26Other spondylosis with radiculopathy, lumbar region
    M48.04Spinal stenosis, thoracic region
    M48.05Spinal stenosis, thoracolumbar region
    M48.07Spinal stenosis, lumbosacral region

    Showing 1–10 of 23

    Related Payer Policy Updates

    Specialty: Neurology/Neurosurgery1 / 3

    10 rows

    PolicyPayerEffective Date
    Clinical Review Criteria Intraoperative Neurophysiological Monitoring (IONM)Kaiser Permanente2027-01-01
    Remote Electrical Neuromodulation for Migraines (i.e., Nerivio®)bcbsvermont2026-11-01
    Lumbar Microdiscectomyuniverahealthcare2026-10-15
    Artificial Cervical Intervertebral Discuniverahealthcare2026-10-15
    Lumbar Decompressionuniverahealthcare2026-10-15
    Responsive Neurostimulation for Focal EpilepsyPremera Bluecross2026-10-14
    Intraoperative MonitoringProvidence Health Plan2026-10-01
    Intraoperative MonitoringProvidence Health Plan2026-10-01
    High-Intensity Focused UltrasoundMass General Brigham Health Plan2026-10-01
    Vagal Nerve StimulationAmbetter Nevada2026-10-01

    Related Codes

    CPT-22100-CERVICAL-VERTEBRAL-POSTERIOR-EXCISION-BONY-LESION

    CPT 22100: Partial Excision of Posterior Cervical Vertebra for Bony Lesion

    CPT-22102-LUMBAR-VERTEBRAL-BONY-LESION-EXCISION

    CPT 22102: Excision of Lumbar Vertebral Bony Lesion

    CPT-22103-EXCISION-POSTERIOR-VERTEBRAL-BONY-LESION

    CPT 22103: Excision of Posterior Vertebral Element for Bony Lesion

    CPT-22110-CERVICAL-VERTEBRAL-BODY-EXCISION-SINGLE-LEVEL

    CPT 22110: Excision of Portions of Cervical Vertebral Body

    CPT-22112-THORACIC-VERTEBRAL-BODY-RESECTION

    CPT 22112: Excision of Thoracic Vertebral Body, Single Level

    CPT-22114-LUMBAR-VERTEBRAL-BODY-EXCISION

    CPT 22114: Excision of Portions of a Single Lumbar Vertebral Body

    CPT-22116-VERTEBRAL-BODY-EXCISION-SINGLE-VERTEBRA

    CPT 22116: Vertebral Body Excision, Single Vertebra

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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