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    v1.0.30
    OpenPayerBilling CodesAutografts/Tissue Cultured AutograftCPT cpt-15121-split-thickness-autograft-additional-100-sq-cm
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    CPT 15121: Split-Thickness Autograft for Face, Scalp, Eyelids, Mouth, Neck, Ears

    Medicare pays $228 and commercial payers pay $1503 on average nationally for this procedure.

    CPT code 15121 describes a split-thickness autograft procedure for the face, scalp, eyelids, mouth, neck, ears, or related regions, covering an additional 100 square cm or less (or 1% body area for infants/children); service type: surgical skin grafting (split-thickness autograft); typical site of service: operating room or surgical suite, including specialty settings for facial, scalp, or digit reconstruction.

    For related coverage guidance, see recent payer policy updates: Mohs Micrographic Surgery, Mohs Micrographic Surgery, Mohs Micrographic Surgery.

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    National Reimbursement Benchmarks

    Nationally, Medicare averages $227.70 for CPT 15121 while BUCA (average commercial) averages $1,503.30, indicating BUCA mean rates sit roughly $1,275.60 above Medicare. This gap highlights substantial upward pressure in some commercial contracts compared with the Medicare baseline, with BUCA clearly representing a higher-cost commercial benchmark versus the federal program.

    Rate dispersion (P75 minus P25) varies materially across payers: Blue Cross Blue Shield shows the widest interquartile spread at $3,059.10 ($3,837.90 - $788.10), followed by BUCA with $1,814.10 ($2,327.50 - $513.40). UnitedHealth Group and Cigna have moderate spreads of $1,936.00 ($396.80 - $203.20) and $179.40 ($359.70 - $180.30) respectively, while Aetna is the tightest at $126.00 ($184.00 - $58.20). These dispersion differences reflect how concentrated or variable commercial reimbursement can be across payers.

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    National Payer Mean Reimbursement Rates

    State Reimbursement Rates

    State: Alaska1 / 51

    Clinical & Coding Specifications

    Clinical Context

    A pediatric patient presents to the burn unit after a thermal injury involving the face and neck with focal full‑thickness skin loss. After initial resuscitation, wound debridement, and optimization of the patient’s hemodynamic and nutritional status, the plastic surgery team plans operative split‑thickness skin autografting to the face and neck. The procedure uses a dermatome to harvest a thin partial‑thickness graft from the thigh, followed by placement and fixation of grafts to cover up to an additional 100 square centimeters (or up to 1% body surface area for an infant/child) of exposed dermis. Typical workflow includes preoperative consent, intraoperative hemostasis and bed preparation, graft harvest and meshing as indicated, securement (sutures, staples, or dressings), and postoperative dressings and admission for wound monitoring. Postoperative care includes graft checks, pain control, physical therapy for facial/hand mobility when relevant, and outpatient follow‑up for graft take and scar management.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    15120Split‑thickness autograft, each additional 100 sq cm, or each additional one percent of body area of infants and children, or part thereof (List separately in addition to code for primary procedure)Billed in addition to the primary graft code when more than the base unit of graft area is harvested/placed; aligns directly with incremental graft sizing for pediatric patients.

    Related Modifiers

    12 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    79Modifier 79 indicates a surgical procedure performed during the postoperative global period of a prior surgery that is unrelated to the original procedure. Per AMA/CPT and CMS guidance, it is…- Use modifier 79 when the same physician (or same‑specialty physician in the same group) performs a surgical procedure during the postoperative global period of a prior surgery and the new procedure…

    Showing 1–10 of 12

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    208600000X
    208800000X
    2086S0122X
    293D00000X
    103TE1100X
    1223D0001X
    146N00000X
    207ZI0100X

    Related Payer Policy Updates

    Specialty: Dermatology1 / 3

    10 rows

    PolicyPayerEffective Date
    Mohs Micrographic Surgerypremerabluecrossofwashington2027-02-05
    Mohs Micrographic Surgerypremerabluecrossofwashington2027-02-05
    Mohs Micrographic Surgerypremerabluecrossofwashington2027-02-05
    FilsuvezCigna2026-11-01
    Destruction of Pre-Malignant Skin LesionsAnthem2026-10-01
    Onychomycosis diagnostic testing and coverageOscar Health2026-10-01
    Treatment of Capillary Malformations (Port Wine Stains)universityofutahhealthplans2026-09-28
    AnzupgoCigna2026-09-15
    Hyperhidrosispriority_health_medicare2026-09-01
    Zevaskyn Coverage for Recessive Dystrophic Epidermolysis BullosaCigna2026-09-01

    Related Codes

    CPT-15040-SKIN-HARVEST-TISSUE-CULTURED-AUTOGRAFT

    CPT 15040: Harvest of Skin for Tissue Cultured Skin Autograft (≤100 cm2)

    CPT-15050-PINCH-GRAFT-SKIN-GRAFTING-SMALL-DEFECT

    CPT 15050: Pinch Graft, Skin, Up to 2 cm

    CPT-15100-SPLIT-THICKNESS-AUTOGRAFT-TRUNK-ARMS-LEGS

    CPT 15100: Split-Thickness Autograft from Trunk/Arms/Legs

    CPT-15101-SPLIT-THICKNESS-AUTOGRAFT-ADDITIONAL-100CM2

    CPT 15101: Split-Thickness Autograft, Additional 100 cm²

    CPT-15110-EPIDERMAL-AUTOGRAFT-TRUNK-ARMS-LEGS

    CPT 15110: Epidermal Autograft, Trunk/Arms/Legs

    CPT-15111-EPIDERMAL-AUTOGRAFT-TRUNK-ARMS-LEGS-ADDITIONAL

    CPT 15111: Epidermal Autograft, Trunk/Arms/Legs (per 100 cm2)

    CPT-15115-EPIDERMAL-AUTOGRAFT-FACE-AND-SENSITIVE-AREAS

    CPT 15115: Epidermal Autograft for Face/Scalp/Hands/Feet

    CPT-15116-EPIDERMAL-AUTOGRAFT-FACE-SCALP-HANDS-FEET

    CPT 15116: Epidermal Autograft for Face, Hands, Feet, Multiple Digits

    CPT-15120-SPLIT-THICKNESS-AUTOGRAFT-FACE-HANDS-FEET

    CPT 15120: Split‑Thickness Autograft, Face/Scalp (first 100 sq cm)

    CPT-15130-DERMAL-AUTOGRAFT-HARVEST-PLACEMENT-TRUNK-ARMS-LEGS

    CPT 15130: Dermal Autograft Harvest and Placement

    Showing 1–10 of 27

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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