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    v1.0.28
    OpenPayerBilling CodesDiseases and Disorders of the Circulatory SystemDRG 298-cardiac-arrest-unexplained-without-cc-mcc
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    Cardiac Arrest, Unexplained without CC/MCC: Inpatient Reimbursement Overview

    DRG 298 applies to unexplained cardiac arrest cases without Major Complication or Comorbidity or Complication or Comorbidity and encompasses admissions where cardiac arrest is the principal diagnosis but no qualifying secondary conditions are present. This grouping matters for inpatient reimbursement because it sets the Centers for Medicare & Medicaid Services prospective payment classification and affects hospital payment for the episode of care.

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    DRG 298 Overview

    DRG 298 covers inpatient admissions for unexplained cardiac arrest without Major Complication or Comorbidity or Complication or Comorbidity. This Diagnosis-Related Group captures cases where cardiac arrest is the principal diagnosis but no additional major or secondary complicating conditions are coded. It matters for Medicare payment because case assignment to DRG 298 determines the base prospective payment amount for the hospital stay and influences resource classification for billing. Accurate coding and documentation affect grouping and reimbursement under Centers for Medicare & Medicaid Services inpatient prospective payment policies.

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    Clinical Trials

    • Acute resuscitation interventions: randomized or pilot studies testing timing, protocols, or devices used during in-hospital or out-of-hospital cardiac arrest resuscitation (for example, comparing advanced airway strategies, titrated vasopressor use, or mechanical CPR adjuncts). These studies focus on the immediate arrest population including adults who experience unexplained cardiac arrest without clear comorbid complications, aiming to improve return of spontaneous circulation and early survival. Results are directly relevant to hospitals and payers because changes in resuscitation practice can alter ICU stay duration, resource intensity, and early mortality rates for this DRG.
    • Diagnostic and prognostic evaluation studies: observational cohorts and prospective diagnostic accuracy research evaluating post-arrest workups such as cardiac imaging protocols, continuous ECG monitoring, genetic testing panels, and biomarker strategies to identify occult causes of unexplained arrest. These trials enroll survivors of unexplained cardiac arrest who are hemodynamically stabilized and seek to stratify risk, identify underlying arrhythmogenic or structural etiologies, and predict neurological and cardiac outcomes. Findings inform targeted downstream care pathways, utilization of specialty testing, and reimbursement decisions around costly diagnostics that affect length of stay and readmission risk.
    • Post-discharge functional and secondary prevention trials: comparative effectiveness or pragmatic trials examining rehabilitation intensity, implantable monitoring strategies, or structured secondary prevention programs (including medication adherence support and remote monitoring) among survivors discharged after unexplained cardiac arrest. These studies enroll patients post-hospitalization to measure long-term survival, recurrent arrest or arrhythmia events, functional recovery, and health-care utilization. Payers and providers use this evidence to design follow-up care bundles, allocate resources for outpatient monitoring or rehabilitation, and potentially reduce costly readmissions tied to this DRG.

    Related Codes

    209-COMPLEX-AORTIC-ARCH-PROCEDURES

    Complex Aortic Arch Procedures: Inpatient Reimbursement Overview

    212-CONCOMITANT-AORTIC-AND-MITRAL-VALVE-PROCEDURES

    Concomitant Aortic and Mitral Valve Procedures: Inpatient Reimbursement Overview

    213-ENDOVASCULAR-ABDOMINAL-AORTA-WITH-ILIAC-BRANCH-PROCEDURES

    Endovascular Abdominal Aorta with Iliac Branch Procedures: Inpatient Reimbursement Overview

    215-OTHER-HEART-ASSIST-SYSTEM-IMPLANT

    Other Heart Assist System Implant: Inpatient Reimbursement Overview

    216-CARDIAC-VALVE-AND-OTHER-MAJOR-CARDIOTHORACIC-PROCEDURES-WITH-CARDIAC-CATHETERIZATION-WITH-MCC

    Cardiac Valve and Other Major Cardiothoracic Procedures with Cardiac Catheterization with MCC: Inpatient Reimbursement Overview

    217-CARDIAC-VALVE-AND-OTHER-MAJOR-CARDIOTHORACIC-PROCEDURES-WITH-CARDIAC-CATHETERIZATION-WITH-CC

    Cardiac Valve and Other Major Cardiothoracic Procedures with Cardiac Catheterization with CC: Inpatient Reimbursement Overview

    218-CARDIAC-VALVE-AND-OTHER-MAJOR-CARDIOTHORACIC-PROCEDURES-WITH-CARDIAC-CATHETERIZATION-WITHOUT-CC-MCC

    Cardiac Valve and Other Major Cardiothoracic Procedures with Cardiac Catheterization without CC/MCC: Inpatient Reimbursement Overview

    219-CARDIAC-VALVE-AND-OTHER-MAJOR-CARDIOTHORACIC-PROCEDURES-WITHOUT-CARDIAC-CATHETERIZATION-WITH-MCC

    Cardiac Valve and Other Major Cardiothoracic Procedures with MCC: Inpatient Reimbursement Overview

    220-CARDIAC-VALVE-AND-OTHER-MAJOR-CARDIOTHORACIC-PROCEDURES-WITHOUT-CARDIAC-CATHETERIZATION-WITH-CC

    Cardiac Valve and Other Major Cardiothoracic Procedures without Cardiac Catheterization with CC: Inpatient Reimbursement Overview

    221-CARDIAC-VALVE-AND-OTHER-MAJOR-CARDIOTHORACIC-PROCEDURES-WITHOUT-CARDIAC-CATHETERIZATION-WITHOUT-CC-MCC

    Cardiac Valve and Other Major Cardiothoracic Procedures without Cardiac Catheterization without CC/MCC: Inpatient Reimbursement Overview

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    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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