Lymphedema is swelling from accumulation of lymphatic fluid due to disrupted lymphatic drainage; it may be primary (congenital) or most often secondary to surgery, radiation, scarring, or other causes. Conservative management includes limb elevation, hygiene, compression therapy (garments, bandaging, pneumatic pumps), manual lymphatic drainage, and complete decongestive therapy. Physiologic microsurgical approaches (for example lymphaticovenular anastomosis, lymphovenous bypass, lymphatico-lymphatic bypass, and vascularized/autologous lymph node transfer) aim to reroute or restore lymphatic flow, while tissue-transfer and reductive/ablative techniques (direct excision and liposuction) remove fibrofatty tissue arising from chronic lymph stasis.
Lipedema is a chronic disorder characterized by disproportionate, often painful subcutaneous fat deposition in the extremities (typically bilateral, sparing the feet) that is frequently unresponsive to weight loss. Conservative care for lipedema includes manual lymphatic drainage, compression stockings, intermittent pneumatic compression, skin care, exercise, and diet when appropriate. Liposuction (including tumescent and specialized techniques such as power-, water-, laser-, ultrasound-, or radiofrequency-assisted) is being investigated as a treatment option for both lipedema and for lymphedema with substantial fibrofatty change.
Reductive procedures such as liposuction remove fibrous and fatty tissue via suction through cannulae and are intended for individuals with advanced disease who have not responded to conservative therapy; postoperative compression garments are required and may be needed indefinitely to maintain volume reduction and the benefits of treatment.