Inflammatory Conditions - Zymfentra Prior Authorization Policy
Prior authorization policy for Zymfentra (infliximab-dyyb subcutaneous injection) covering FDA-approved indications Crohn's disease and ulcerative colitis in adults, specifying initial and continuation criteria, prescriber requirements, approval durations, and situations not recommended for approval including concurrent use with other biologics or targeted synthetic oral small molecule drugs.
Selected revision 02/11/2026 (history entry) after prior selected revisions and annual reviews.
Annual Revision 12/17/2025: Appendix: Otezla XR (apremilast-extended release tablets) was added.
Selected Revision 07/23/2025: Ulcerative Colitis initial therapy options removed previously.
Selected Revision 02/11/2026: Most recent selected revision date listed in header.