CurrentBlue Cross Blue Shield - OklahomaPolicy CPCPLAB034

Salivary Hormone Testing

Defines Blue Cross Blue Shield of Oklahoma's reimbursement stance and coding guidance for salivary hormone testing for members and providers across applicable products; providers should review plan documents for product-specific applicability.

Policy Summary

PayerBlue Cross Blue Shield - Oklahoma

PolicySalivary Hormone Testing

Policy CodePolicy CPCPLAB034

Change TypeCodes added and removedliterature review

Effective DateAug 8, 2025

Next Review Date

Key ActionProviders must submit accurate documentation and provide additional documentation upon request; claims are subject to code edit protocols and plan/contract terms.

SourceLink

POLICY UPDATE CHANGES

Removed the following codes: 82626, 82627, 82670, 82671, 82672, 82677, 82679, 82681, 84144, 84402, 84403, 84410.

Added code 0462U.

Document updated with literature review; reimbursement information unchanged.

1diagnosis reimbursable indication listed

11diagnoses/uses not reimbursable

5codes enumerated

10+reference items cited

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Reimbursement Criteria

Reimbursement criteria

Reimbursement guidance by indication:

ALL of the following

ONE of
- Diagnosis of Cushing syndrome with late‑night salivary cortisol testing; may be reimbursable for this indication.

ALL of the following

NONE of the following
- Screening, diagnosis, or monitoring of menopause.
- Infertility.
- Endometriosis.
- Polycystic ovary disease (PCOS).
- Premenstrual syndrome (PMS).
- Osteoporosis.
- Sexual dysfunction.
- Seasonal affective disorder (SAD).
- Depression.
- Multiple sclerosis (MS).
- Sleep disorders.
- Diseases related to aging.

Procedure and Code Guidance

Listed procedure codesCPT

82530
82533
0462U
S3650
S3652

Code list completeness and reimbursement note

Scope of code listThe procedure code list is not all‑encompassing; codes shown are examples and other codes may apply.

No guarantee of coverageInclusion of a code in this policy does not guarantee the code is a covered service or eligible for reimbursement.

Provider responsibilityProviders must submit claims using valid code combinations from HIPAA‑approved code sets and code appropriately per industry coding guidelines.

Claims subject to editsClaims are subject to code edit protocols and plan/contract terms; appropriate coding may be reviewed and adjusted.

Plan‑specific applicabilityNot all code list requirements apply to each product; providers should verify product‑specific coverage in plan documents.

Documentation and Claim Submission

Documentation Required

Documentation, coding accuracy, and potential claim edits/requests

Providers are responsible for submission of accurate documentation of services performed and must submit claims using valid, appropriately coded combinations from HIPAA‑approved code sets. Claims are subject to code edit protocols and review against benefit terms, provider contracts, medical policies, coding policy and coding software logic; upon request, providers should submit additional documentation to support the claim.

Submit claims using valid code combinations from HIPAA‑approved code sets (CPT, HCPCS, ICD‑10, NDC, DRG, etc.).
Claims may be edited or denied per code edit protocols, benefit terms, provider contract language, medical and clinical payment/coding policies, and coding software logic.
If requested, promptly provide additional documentation to support medical necessity and claim coding.

Plan Documents and Governing Materials

Plan documents and precedence

What 'Plan documents' includeCertificates of Health Care Benefits, benefit booklets, Summary Plan Descriptions, and other coverage documents.

Hierarchy of governanceIf a conflict exists between this Clinical Payment and Coding Policy and a plan document under which a member is entitled to Covered Services, the plan document will govern.

Provider contract precedenceIf a conflict arises between this policy and any provider contract, the provider contract will govern with respect to that provider's participation and services.

Recommendation to providersProviders are urged to review plan documents to determine eligible coverage for services rendered, as requirements may vary by product.