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Meniere's Disease and Related Disorders: Surgery
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Defines Aetna's medical necessity and investigational determinations for surgical interventions for chronic refractory Meniere's disease and related disorders, and lists applicable procedure and diagnosis codes; applies to Aetna members.
No material clinical or coverage changes in this revision.
Coverage and Medical Necessity Criteria
Medically necessary surgical interventions for chronic refractory Meniere's disease
Aetna considers any of the following surgical interventions medically necessary for treatment of chronic refractory Meniere's disease (selection criteria referenced in the Appendix):
Ablative treatments are relatively contraindicated for bilateral Meniere's disease due to risk of bilateral vestibular and cochlear hypofunction.
Surgical treatment for superior semicircular canal dehiscence
Covered when diagnosis is confirmed by audiometry and computed tomography (CT):
Pre- and post-operative VEMP and audiometry are used to confirm affected ear and assess outcomes.
Intra-tympanic / trans-tympanic dexamethasone injection
Covered indication:
Salvage intratympanic glucocorticoid therapy is suggested for inadequate response to initial treatment within 6–8 weeks.
Procedures considered experimental and investigational
Aetna considers the following procedures investigational for chronic refractory Meniere's disease because effectiveness has not been established:
These procedures are considered investigational and not covered because effectiveness has not been established.
Procedures lacking evidence
Not supported procedures based on cited determinations:
UpToDate reviews do not mention cochleostomy as a therapeutic option.
Intratympanic therapies (gentamicin vs glucocorticoids)
Evidence-based comparative findings for intratympanic injections:
Meta-analysis pooled multiple RCTs; see systematic review and RCTs cited.
Meta-analysis results reported improved PTA and SDS with glucocorticoids versus gentamicin.
Randomized comparative trial of 60 patients with 2-year follow-up.
Endolymphatic sac procedures
Outcomes reported for endolymphatic sac drainage with or without intra-sac steroids:
Study sizes and follow-up durations vary across reports.
Longitudinal cohort data cited (Kitahara et al, Yu et al).
Tenotomy of middle ear muscles (TSTM)
Evidence for tenotomy of middle ear muscles (TSTM):
Studies are small and preliminary; larger randomized trials are needed.
UpToDate citation included (Moskowitz and Dinces).
Destructive procedures and cochlear implantation
Destructive procedures and cochlear implantation — outcomes and considerations:
Comparative retrospective studies report high vertigo control and differing hearing preservation between procedures.
Reports describe small series with preliminary positive outcomes but limited data.
Evidence summaries
Summaries of clinical evidence for procedures and intratympanic therapies:
Level of evidence for comparative retrospective work cited as III in Li et al.
VEMP and audiometry are useful diagnostic and outcome measures.
Single-case report cited; broader reviews do not support use.
UpToDate recommends salvage IT glucocorticoid within 6–8 weeks for inadequate initial response.
Certainty rated very low; follow-up and trial conduct limitations noted.
Selection Criteria for Surgery for Meniere's Disease
Surgical intervention may be considered when ALL of the following are met:
Documentation must support chronic refractory Meniere's disease and, where applicable, confirm diagnosis for related disorders.
The National Coverage Determination (NCD) for “Cochleostomy with Neurovascular Transplant for Meniere's Disease” states there is no scientific evidence supporting the safety and effectiveness of cochleostomy with neurovascular transplant for treatment of Meniere's disease; accordingly, Medicare does not cover this procedure.
Restating the Medicare exclusion: cochleostomy with neurovascular transplant for Meniere's disease is specifically excluded by the NCD because evidence does not demonstrate safety or effectiveness, and thus this procedure is not supported for coverage.
Triple semicircular canal plugging (TSCP) has been reported in retrospective series with high vertigo control rates, but the procedure is not mentioned as a therapeutic option in an UpToDate review (Moskowitz and Dinces, 2017), indicating limited recognition in that clinical reference and that the findings remain preliminary.
Labyrinthectomy is a destructive procedure reserved for patients with unilateral disease and is applicable only when hearing in the involved ear is severe to profound; it is relatively contraindicated for bilateral Meniere's disease because ablative treatments risk bilateral vestibular and cochlear hypofunction.
Aetna considers the following procedures investigational and therefore not medically necessary for chronic refractory Meniere's disease because effectiveness has not been established: cochleostomy with neurovascular transplant; intra-tympanic dexamethasone thermos-sensitive gel; positive pressure therapy to improve endolymphatic sac surgery outcomes; simultaneous labyrinthectomy with cochlear implantation (for bilateral disease); tenotomy of the stapedius and tensor tympani muscles; and triple semi-circular canal plugging.
Procedures that lack supporting scientific evidence (for example, cochleostomy with neurovascular transplant) are not supported by Medicare and would be considered not medically necessary for treatment of Meniere's disease.
UpToDate and recent reviews list the positive pressure pulse generator among therapies they would not use for Meniere's disease; a Cochrane review concluded evidence for positive pressure therapy is of low or very low certainty and remains very uncertain.
Procedures and device codes referenced in this policy (see Coding section) include a list of CPT, HCPCS and ICD-10 codes for covered and not-covered services (for example CPT codes for labyrinthotomy, endolymphatic sac operations, labyrinthectomy and cochlear implantation, and HCPCS code E2120 for a pulse generator system); refer to the policy coding tables for the full code list and specific coverage notes.
Procedure, Device, and Diagnosis Codes
| 61590 | Infratemporal pre-auricular approach to middle cranial fossa (parapharyngeal space, infratemporal and midline skull base, nasopharynx), with or without disarticulation of the mandible, including parotidectomy, craniotomy, decompression and/or mobilization of the facial nerve and/or petrous carotid artery. |
| 61591 | Infratemporal post-auricular approach to middle cranial fossa (internal auditory meatus, petrous apex, tentorium, cavernous sinus, parasellar area, infratemporal fossa) including mastoidectomy, resection of sigmoid sinus, with or without decompression and/or mobilization of contents of auditory canal or petrous carotid artery. |
| 61592 | Orbitocranial zygomatic approach to middle cranial fossa (cavernous sinus and carotid artery, clivus, basilar artery or petrous apex) including osteotomy of zygoma, craniotomy, extra- or intradural elevation of temporal lobe. |
| 64716 | Neuroplasty and/or transposition; cranial nerve (specify) [vestibular (non-destructive to hearing)]. |
| 69433 | Tympanostomy (requiring insertion of ventilating tube), local or topical anesthesia. |
| 69436 | Tympanostomy (requiring insertion of ventilating tube), general anesthesia. |
| 69676 | Tympanic neurectomy. |
| 69801 | Labyrinthotomy, with perfusion of vestibuloactive drug(s); transcanal [intra-typmanic gentamicin]. |
| 69805 | Endolymphatic sac operation; without shunt. |
| 69806 | Endolymphatic sac operation; with shunt. |
| H81.01-H81.09 | Meniere's disease [active]. |
| H83.8x1-H83.8x9 | Other specified diseases of inner ear [superior semicircular canal dehiscence]. |
| H90.3-H90.A32 | Conductive and sensorineural hearing loss. |
| E2120 | Pulse generator system for tympanic treatment of inner ear endolymphatic fluid. |
| Dexamethasone thermos-sensitive gel | No specific code listed |
| Tenotomy of the stapedius and tensor tympani muscles | No specific code listed |
| Semi-circular canal plugging | No specific code listed |
| Not specified | Cochleostomy with neurovascular transplant (No scientific evidence supporting safety and effectiveness; Medicare NCD does not cover). |
| Not specified | Intratympanic methylprednisolone or dexamethasone injections/perfusions (studied in RCTs and systematic reviews). |
| Not specified | Intratympanic gentamicin (comparative effectiveness trial evidence). |
| Not specified | Cochlear implantation, including cases combined with labyrinthectomy in select situations (reported in small series). |
| Not specified | Labyrinthectomy, vestibular neurectomy, semicircular canal plugging (TSCP/SCP). |
| Not specified | Tenotomy of stapedius and tensor tympani muscles (TSTM). |
| Not specified | Endolymphatic sac drainage/shunt (with or without intra-sac steroids). |
Prior Authorization, Documentation, and Clinical Workflow
Prior authorization — procedure and device codes
Providers must verify prior authorization requirements and submit authorizations where required before scheduling procedures or obtaining devices related to Meniere's disease and related disorders surgery. Covered and non-covered CPT/HCPCS/ICD-10 codes are listed in the policy's coding tables and should be referenced when requesting prior authorization.
- Verify prior authorization for listed CPT codes (e.g., 61590, 61591, 61592, 64716, 69433, 69436, 69676, 69801, 69805, 69806, 69905, 69910, 69915, 69950, 69930) as applicable
- Check HCPCS and device codes (e.g., L8614-L8629, E2120) and coverage status before procurement or billing
- Use policy number 0514 reference when submitting authorization requests
Prior authorization considerations for uncommon/experimental procedures
When requesting prior authorization for uncommon or experimental procedures, include a clear clinical rationale and supporting literature. Procedures identified as experimental/investigational by Aetna (see list) are at high risk of denial; obtain medical director review if pursuing authorization.
- Examples at high denial risk: cochleostomy with neurovascular transplant; intra-tympanic dexamethasone thermo-sensitive gel; positive pressure therapy to improve endolymphatic sac surgery outcomes; simultaneous labyrinthectomy with cochlear implantation; tenotomy of stapedius/tensor tympani; triple semi-circular canal plugging
- Medicare NCD: cochleostomy with neurovascular transplant is not covered
Prior authorization for salvage intratympanic steroid therapy
For sudden sensorineural hearing loss (SSNHL) salvage intratympanic glucocorticoid therapy should be considered only after inadequate response to initial therapy. Timing and prior treatments must be documented when requesting authorization.
- Salvage intratympanic glucocorticoid injections are suggested for patients with <10 dB improvement or persistent ≥20 dB hearing loss after initial therapy
- Treatment is ideally initiated within 6–8 weeks of symptom onset
- If initial therapy was systemic glucocorticoids, intratympanic salvage is appropriate; no additional glucocorticoid therapy if initial treatment included both systemic and intratympanic glucocorticoids
Investigational procedures — denial risk
Aetna considers certain procedures experimental/investigational; requests for these procedures are likely to be denied. Provide strong evidence if seeking exception and expect additional review.
- Procedures listed as investigational include cochleostomy with neurovascular transplant, intra-tympanic dexamethasone thermo-sensitive gel, positive pressure therapy adjuncts, simultaneous labyrinthectomy with cochlear implantation, tenotomy of stapedius/tensor tympani, and triple semi-circular canal plugging
- Medicare does not cover cochleostomy with neurovascular transplant for Meniere's disease per NCD
Insufficient follow-up may affect evidence acceptability
Clinical evidence used to support requests should meet follow-up and reporting standards. Studies with insufficient follow-up were routinely excluded from systematic reviews and may weaken the case for coverage.
- Cochrane-style reviews excluded trials with follow-up <3 months; provide adequate follow-up data when citing studies
- Very low-certainty evidence from small trials may not support coverage for novel approaches
Prior authorization for surgery — selection criteria required
Before scheduling surgical interventions for Meniere's disease, confirm that selection criteria are met. Lack of documentation demonstrating these criteria may result in denial of authorization or payment.
- Selection criteria required prior to surgery scheduling: disabling vertigo; symptoms for ≥2 years; failed conservative management; unilateral disease (labyrinthectomy only when severe–profound hearing loss in involved ear)
- Document failure of dietary (low-sodium, avoid caffeine/alcohol/nicotine) and medical therapies (diuretics, anti-emetics, vestibular suppressants)
No explicit prior authorization requirements stated in some excerpts
Some excerpts in the policy do not state explicit prior authorization or denial rules; in those cases follow standard plan prior-auth processes or contact Aetna for clarification.
- When prior authorization language is not explicit in a section, use the coding tables and Appendix selection criteria as the operational guide
- Contact Aetna provider services or use the member's plan portal to confirm prior authorization requirements
Clinical documentation to justify surgery
Document chronic refractory disease and diagnostic confirmation clearly in the medical record to justify surgical interventions. Provide audiometric and vestibular testing results, duration of symptoms, and prior conservative treatments.
- Document chronicity (≥2 years), disabling vertigo, and failure of conservative therapy
- Provide rationale for chosen surgical approach (destructive vs non-destructive) and risk/benefit discussion
Required clinical documentation for surgical interventions
Required clinical documentation for surgical interventions should include preoperative diagnostic testing, operative details, and objective outcome measures to support medical necessity and for post-operative review.
- Audiometric testing (pure tone audiometry, speech discrimination) and documentation of air–bone gap where relevant
- Vestibular testing results (caloric testing, VEMP thresholds, cVEMP/oVEMP) and vestibular function assessments
- Operative reports describing procedure type, approach (middle fossa, transmastoid), and any device implantation
- Post-operative follow-up data (audiometry, VEMP changes, vertigo control) when available
Preoperative diagnostic testing and documentation for SSCD
For superior semicircular canal dehiscence (SSCD), submit detailed preoperative diagnostic testing: symptom description, audiometry, high-resolution CT, and VEMP testing results to confirm diagnosis and document the target ear for surgery.
- Symptoms: sound- or pressure-induced vertigo, oscillopsia, and demonstration of sound/pressure-evoked eye movements
- Audiometry showing air–bone gap or other relevant findings
- High-resolution CT demonstrating bony dehiscence of the superior semicircular canal
- cVEMP and/or oVEMP thresholds (air- and bone-conducted) showing pathologically lowered thresholds to support diagnosis and to lateralize the worse ear
Required documentation for surgical eligibility
Required documentation for surgical eligibility must confirm disabling vertigo, chronicity of symptoms, and failure of conservative management. Missing these elements may lead to non-coverage for surgical interventions.
- Disabling vertigo documented in history and functional impact
- Symptoms present for at least 2 years
- Evidence of failed conservative management: dietary measures, diuretics, vestibular suppressants, and other medical therapy
- For labyrinthectomy, document unilateral disease with severe-to-profound hearing loss in the involved ear
No documentation requirements present in some excerpts
Some administrative or informational excerpts in the policy contain no explicit documentation requirements. When absent, rely on the policy's coding, selection criteria, and clinical sections for documentation expectations.
- Use policy Appendix and background sections as the primary source for documentation requirements when not restated elsewhere
- Contact Aetna for case-specific documentation guidance if uncertain
Therapeutic sequencing guidance
Therapeutic sequencing should be documented: conservative measures first; for intra-tympanic options weigh methylprednisolone (hearing-preserving) versus gentamicin (vestibular ablation with hearing risk) based on clinical goals and hearing status.
- Document trials of dietary sodium restriction, diuretics, vestibular suppressants, and other medical management prior to intra-tympanic or surgical interventions
- When selecting intra-tympanic therapy, note that glucocorticoids are generally less destructive to hearing than gentamicin and may be preferred when hearing preservation is important
Step therapy for sudden sensorineural hearing loss
Step therapy for SSNHL: initial systemic glucocorticoids are first-line; intratympanic glucocorticoids are an accepted salvage option for inadequate responders. Document prior systemic therapy when requesting intratympanic salvage treatment.
- Initial therapy: systemic glucocorticoids for SSNHL unless contraindicated
- Salvage: intratympanic glucocorticoids within 6–8 weeks for inadequate response to systemic therapy
- If initial treatment included both systemic and intratympanic glucocorticoids, further glucocorticoid therapy is not recommended
No step therapy requirements stated in these excerpts
No formal step therapy requirements beyond those described in the clinical guidance are stated in some policy excerpts; follow the clinical sequencing guidance above and the member's benefit plan for any utilization management rules.
- Where step-therapy language is absent, use standard clinical sequencing (systemic → intratympanic salvage) and confirm any plan-specific utilization management rules
- Contact Aetna for exceptions or case-by-case prior authorization inquiries
Background and Context
Meniere's disease is an inner ear disorder characterized by episodic vertigo, tinnitus, aural fullness and progressive hearing loss associated with endolymphatic hydrops. Conservative management — including dietary sodium restriction, diuretics and vestibular suppressants — is first-line; surgical intervention is considered for disabling vertigo refractory to medical and dietary therapy, with choice of procedure influenced by hearing status and laterality.
Definitions and Key Terms
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