Summary & Overview

Appendix Procedures with CC: Inpatient Reimbursement Overview

DRG 398 encompasses appendix procedures with a Complication or Comorbidity and includes appendectomies accompanied by additional documented clinical conditions that increase resource use. Proper identification of this Diagnosis-Related Group is important for inpatient reimbursement because the Complication or Comorbidity status affects relative payment under Medicare's inpatient prospective payment system.

Appendix Procedures with CCDRG Appendix Procedures with CCDRG 398Diagnosis-Related GroupInpatient ReimbursementMedicareGeneral SurgeryAppendectomySurgical CodingHospital Payment

DRG 398 Overview

DRG 398 covers inpatient stays involving appendix procedures accompanied by a Complication or Comorbidity. This Diagnosis-Related Group captures cases where surgical management of appendiceal disease requires additional resources due to coexisting clinical conditions. It matters for Medicare payment because the presence of a Complication or Comorbidity elevates the relative resource use and thus influences the hospital reimbursement assigned under the inpatient prospective payment system. Accurate coding of the appendix procedure and associated comorbidities determines payment eligibility for this Diagnosis-Related Group.

Clinical Trials

Randomized or prospective studies of acute operative approaches for complicated appendicitis (e.g., open versus laparoscopic appendectomy, timing of appendectomy after diagnosis, or percutaneous drainage plus interval appendectomy). These trials enroll adults and children presenting with appendicitis complicated by perforation, abscess, or generalized peritonitis and aim to determine optimal timing, surgical approach, or need for initial nonoperative source control. Findings inform hospital resource use, length of stay, and complication rates — key drivers of inpatient reimbursement and case-mix costs under this DRG.
Comparative effectiveness research evaluating nonoperative management versus surgical intervention for complicated appendicitis with concomitant comorbidities (for example, patients with significant cardiopulmonary disease, immunosuppression, or advanced age). These cohort studies or pragmatic trials assess clinical resolution, readmission, escalation to surgery, and complication burden in patients initially treated with antibiotics and image-guided drainage versus immediate appendectomy. Results are directly relevant to payers and care managers because they influence short-term costs, ICU utilization, and downstream readmissions captured in episode payments for DRG 398.
Post-discharge outcomes and quality-of-care studies focusing on complication surveillance, functional recovery, and health-system utilization after inpatient treatment for complicated appendicitis. These observational studies track surgical site infections, hernia, bowel obstruction, and unplanned healthcare visits in the weeks to months after discharge, often stratified by severity of intra-abdominal infection and presence of CCs (complicating conditions). Understanding these patterns helps providers improve discharge planning and bundled-payment performance, and helps payers predict post-acute costs and identify opportunities to reduce readmissions and avoidable complications.

Related Codes

397-APPENDIX-PROCEDURES-WITH-MCC

Appendix Procedures with Major Complication or Comorbidity: Inpatient Reimbursement Overview

344-MINOR-SMALL-AND-LARGE-BOWEL-PROCEDURES-WITH-MCC

Minor Small and Large Bowel Procedures with MCC: Inpatient Reimbursement Overview

326-STOMACH-ESOPHAGEAL-AND-DUODENAL-PROCEDURES-WITH-MCC

Stomach, Esophageal and Duodenal Procedures with MCC: Inpatient Reimbursement Overview

336-PERITONEAL-ADHESIOLYSIS-WITH-CC

Peritoneal Adhesiolysis with CC: Inpatient Reimbursement Overview

355-HERNIA-PROCEDURES-EXCEPT-INGUINAL-AND-FEMORAL-WITHOUT-CC-MCC

Hernia Procedures Except Inguinal and Femoral without CC/MCC: Inpatient Reimbursement Overview

351-INGUINAL-AND-FEMORAL-HERNIA-PROCEDURES-WITH-CC

Inguinal and Femoral Hernia Procedures with CC: Inpatient Reimbursement Overview

379-GASTROINTESTINAL-HEMORRHAGE-WITHOUT-CC-MCC

Gastrointestinal Hemorrhage without CC/MCC: Inpatient Reimbursement Overview

358-OTHER-DIGESTIVE-SYSTEM-O-R-PROCEDURES-WITHOUT-CC-MCC

Other Digestive System O.R. Procedures without CC/MCC: Inpatient Reimbursement Overview

331-MAJOR-SMALL-AND-LARGE-BOWEL-PROCEDURES-WITHOUT-CC-MCC

Major Small and Large Bowel Procedures without CC/MCC: Inpatient Reimbursement Overview

388-GASTROINTESTINAL-OBSTRUCTION-WITH-MCC

Gastrointestinal Obstruction with MCC: Inpatient Reimbursement Overview

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