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    v1.0.28
    OpenPayerBilling CodesVision ServicesHCPCS hcpcs-v2785-corneal-tissue-processing-preservation-transport
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    HCPCS Level II V2785: Processing, Preserving and Transporting Corneal Tissue

    HCPCS Level II code V2785 describes the professional service of processing, preserving, and transporting corneal tissue for transplantation or research, a tissue-banking service that involves preparation and handling of donor corneas; service type: tissue processing and preservation, typical site of service: eye bank or specialized tissue processing facility.

    For related coverage guidance, see recent payer policy updates: Evaluation of Dry Eyes, Evaluation of Dry Eyes, Ophthalmic Prostaglandin Analog Prior Authorization Criteria.

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    Table of contents

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    • Billing CodesCPT, HCPCS, DRG & more
    • Reimbursement RatesCommercial vs. Medicare rate reports
    • ProvidersHospitals & facilities
    • PayersPlans & market footprint
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    • ModifiersCPT modifiers & usage
    • Prior AuthorizationPA policies by payer & drug
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    Clinical & Coding Specifications

    Clinical Context

    A donor cornea is recovered at an eye bank or affiliated surgical center, then undergoes processing, preservation, and packaging for transport to a transplanting surgeon. Typical workflow: the recovered tissue arrives at the eye bank; trained technicians screen donor medical history and serologies, perform sterile dissection (including scleral rim trimming), evaluate endothelial cell count and corneal clarity using specular microscopy or slit-lamp, apply preservation solution (e.g., Optisol-GS) and place tissue in a sterile container; label and document chain-of-custody and regulatory forms; arrange temperature-controlled transport to the recipient hospital or ambulatory surgery center. Typical patient scenario: a 68-year-old patient with advanced Fuchs endothelial corneal dystrophy is scheduled for Descemet membrane endothelial keratoplasty (DMEK). The surgeon orders pre-screened, preserved donor corneal tissue from an accredited eye bank. The eye bank bills for processing, preserving, and transporting corneal tissue (V2785). Typical site of service: eye bank laboratory and courier transport to hospital or ambulatory surgery center. Typical personnel: eye bank technicians, medical director (ophthalmologist), courier services. Required documentation: donor consent and screening records, serology reports, tissue evaluation (endothelial cell density), preservation method and expiration, shipping manifest, recipient surgeon order, chain-of-custody record.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    65710Keratoplasty (corneal transplant) full-thickness penetrating graftReceives donor corneal tissue after processing; primary procedure that follows tissue supply.
    65756Keratoplasty, anterior lamellar, partial-thickness (deep anterior lamellar keratoplasty)Uses prepared donor tissue for partial-thickness anterior grafts; coordinated with eye bank-supplied tissue.
    65755Keratoplasty, endothelial (e.g., DSEK, DMEK)Endothelial keratoplasty procedures that specifically require endothelial cell layer–prepared donor tissue provided after V2785 processing.
    99070Supplies and materials (e.g., sterile tissue handling supplies)Reimburses expendable supplies used during surgical implantation of the processed cornea; ancillary to tissue processing and transplantation.
    36415Collection of venous blood by venipuncturePerformed at donor screening to obtain serology samples required for tissue release; part of pre-processing workflow.

    Related Modifiers

    9 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    80CPT® Modifier 80 (Assistant Surgeon) is appended to a surgical CPT code when a physician (MD or DO) provides full, continuous assistance throughout the operative procedure. It is intended only for…- Use CPT Modifier -80 when a physician (MD or DO) serves as an assistant surgeon and provides full, continuous assistance throughout the entire operative procedure; append -80 to the surgical CPT…

    Related Provider Taxonomies

    8 rows

    Taxonomy CodeSpecialtyNotes
    363L00000XNurse Practitioner(1) A registered nurse provider with a graduate degree in nursing prepared for advanced practice involving independent and interdependent decision mak…
    335E00000XProsthetic/Orthotic SupplierAn organization that provides prosthetic and orthotic care which may include, but is not limited to, patient evaluation, prosthesis or orthosis design…
    163WD0400XDiabetes Educator Registered NurseNursing Service Providers · Registered Nurse
    363LP0222XCritical Care Pediatric Nurse PractitionerPhysician Assistants & Advanced Practice Nursing Providers · Nurse Practitioner
    106E00000XAssistant Behavior AnalystAn assistant behavior analyst is qualified by Behavior Analyst Certification Board certification and/or a state-issued license or credential in behavi…
    2279E1000XEducational Registered Respiratory TherapistThe focus of patient and family education activities is to promote knowledge of disease process, medical therapy, and self help. Respiratory therapis…
    302R00000XHealth Maintenance Organization(1) A form of health insurance in which its members prepay a premium for the HMO's health services which generally include inpatient and ambulatory ca…
    207RA0002XAdult Congenital Heart Disease PhysicianA physician who specializes in the care and treatment of adults with congenital heart disease. Adult congenital heart disease (ACHD) physicians are tr…

    Related ICD-10-CM Codes

    13 rows

    ICD-10-CM CodeDescription
    H16.221Keratoconjunctivitis sicca, not specified as Sjogren's, right eye
    H16.223Keratoconjunctivitis sicca, not specified as Sjogren's, bilateral
    H17.00Adherent leukoma, unspecified eye
    H17.01Adherent leukoma, right eye
    H18.10Bullous keratopathy, unspecified eye
    H18.12Bullous keratopathy, left eye
    H18.20Unspecified corneal edema
    H18.30Unspecified corneal membrane change
    H18.49Other corneal degeneration
    H18.9Unspecified disorder of cornea

    Showing 1–10 of 13

    Related Payer Policy Updates

    Specialty: Ophthalmology/Optometry1 / 2

    10 rows

    PolicyPayerEffective Date
    Evaluation of Dry EyesOscar Health2026-10-01
    Evaluation of Dry EyesBlue Cross Blue Shield - New Mexico2026-09-04
    Ophthalmic Prostaglandin Analog Prior Authorization Criteriamedimpact2026-09-01
    revakinagene taroretcel-lwey (Encelto) coverage for idiopathic macular telangiectasia (MacTel) type 2blue cross blue shield - louisiana2026-09-01
    Glaucoma ProstaglandinsCigna2026-08-15
    Corneal Cross‑linking (CXL) Procedurehusky_health2026-08-01
    Corneal surgical procedures (excluding corneal collagen cross-linking)husky_health2026-08-01
    Intracanalicular and Intravitreal Corticosteroid ImplantsUnitedHealthcare2026-08-01
    Eye Optical Coherence TomographyPremera Bluecross2026-08-01
    Susvimo (ranibizumab) intravitreal implant — Medical Benefit Drug PolicyUnitedHealthcare2026-08-01

    Related Codes

    HCPCS-LEVEL-II-V2211-SPHEROCYLINDER-BIFOCAL-HIGH-SPHERE

    HCPCS Level II V2211: Spherocylinder Bifocal Lens, High Sphere Range

    HCPCS-LEVEL-II-V2700-BALANCE-LENS-PER-LENS

    HCPCS Level II V2700: Balance Lens, Per Lens

    HCPCS-V2020-FRAMES-PURCHASES

    HCPCS Level II V2020: Frames, Purchases

    HCPCS-V2025-DELUXE-FRAME-VISION-APPLIANCE

    HCPCS V2025: Deluxe Frame

    HCPCS-V2100-SINGLE-VISION-SPHERE-LENS-PLANO-TO-PLUS-MINUS-4

    HCPCS V2100: Single Vision Sphere Lens, Plano to ±4.00 per Lens

    HCPCS-V2101-SINGLE-VISION-SPHERICAL-LENS-HIGH-POWER

    HCPCS Level II V2101: Sphere Single Vision High-Power Lens

    HCPCS-V2102-HIGH-POWER-SINGLE-VISION-SPHERICAL-LENS

    HCPCS V2102: Single-Vision High-Power Spherical Lens

    HCPCS-V2103-SPHEROCYLINDER-SINGLE-VISION-LENS

    HCPCS Level II V2103: Single-Vision Spherocylinder Lens, Per Lens

    HCPCS-V2104-SPHEROCYLINDER-SINGLE-VISION-LENS-PLANO-TO-4D-SPHERE-2-12-TO-4D-CYLINDER

    HCPCS V2104: Spherocylinder Single-Vision Lens, Per Lens

    HCPCS-V2105-SPHEROCYLINDER-SINGLE-VISION-LENS

    HCPCS Level II V2105: Spherocylinder Single-Vision Lens

    Showing 1–10 of 123

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    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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