Summary & Overview
HCPCS Q4349: Mantle Dermal Matrix, Per Square Centimeter
HCPCS Level II code Q4349 designates a mantle dermal matrix billed per square centimeter as an add-on service to be reported in addition to a primary procedure. This code captures use of a dermal matrix product applied during reconstructive or wound-management procedures to support soft-tissue regeneration. Nationally, accurate coding of add-on product charges like Q4349 matters for clinical documentation, device tracking, and correct aggregation of procedural costs associated with advanced wound care and reconstructive surgeries.
Key payers covered in this overview include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find a concise explanation of the code’s clinical context, typical sites of service, and how the code functions as an add-on to primary procedures. The publication also outlines common billing considerations and the types of benchmarks and policy updates one should expect when evaluating coverage and reimbursement for dermal matrix products. Where specific payer policy details, taxonomies, ICD-10 mappings, or related codes are not provided in the source data, the text indicates that those items are not available in the input.
Billing Code Overview
HCPCS Level II code Q4349 describes a mantle dermal matrix billed per square centimeter as an add-on procedure, intended to be listed separately in addition to a primary procedure. The service type is dermal matrix placement/skin substitute application, used when a biologic or synthetic matrix is applied to a wound or surgical site to support tissue regeneration. The typical site of service is an operating room or procedure suite within an acute care hospital or ambulatory surgical center where primary reconstructive or wound procedures are performed.
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Clinical & Coding Specifications
Clinical Context
A patient with a full-thickness skin defect after oncologic resection of a cutaneous malignancy on the trunk is scheduled for reconstruction using a dermal regeneration matrix component. The surgical team prepares the primary procedure (e.g., excision and flap/graft placement) in the operating room. After achieving hemostasis and appropriate wound bed preparation, the surgeon measures the defect in square centimeters and applies a Mantle dermal matrix product as an add-on biologic to support dermal regeneration and promote integration beneath a split-thickness skin graft or local flap. The billing for the matrix material is reported per square centimeter using Q4349 in addition to the primary procedure code. Typical perioperative workflow includes sterile handling of the matrix, placement to cover the defect with secure fixation (sutures or staples as needed), application of an appropriate dressing, and documentation of matrix area (cm2), lot number, and manufacturer on the operative report and implant log. Postoperative care includes routine wound checks, dressing changes, and documentation of graft take and matrix incorporation over subsequent clinic visits. Typical site of service is an inpatient or outpatient operating room or ambulatory surgery center for reconstructive or dermatologic surgery.
Coding Specifications
| Modifier | Description | When to Use |
|---|---|---|
00 | No modifier (default) | Use when no special circumstances apply to the service reported with . |