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    v1.0.28
    OpenPayerBilling CodesTemporary CodesHCPCS hcpcs-q4344-tri-membrane-wrap-add-on-per-cm
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    HCPCS Q4344: Tri-membrane Wrap, Per Square Centimeter

    HCPCS Level II code Q4344 describes a tri-membrane wrap billed per square centimeter as an add-on supply used in surgical wound or graft procedures; the service type is a surgical adjunct/material and the typical site of service is an operating room or procedure suite where the primary procedure requiring the membrane is performed.

    For related coverage guidance, see recent payer policy updates: B-Hemolytic Streptococcus Testing, Human Immunodeficiency Virus (HIV) — Coverage Criteria for Testing and Resistance Assays, Hepatitis Testing (A, B, C, D) Coverage Criteria.

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    • Billing CodesCPT, HCPCS, DRG & more
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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is an adult undergoing reconstructive or complex wound closure following surgical excision (for example oncologic resection, infected hardware removal, or traumatic debridement) where a biologic tri-membrane wrap is applied to reinforce soft tissue, protect repaired structures, or augment a tendon/nerve/vascular repair. The procedure is performed in an operating room or ambulatory surgical center under sterile conditions, typically by orthopedic, plastic, or general surgeons. The workflow includes preoperative evaluation and consent, intraoperative measurement of the defect or repair site in square centimeters to determine the quantity of Q4344 material to bill (add-on per cm2), placement of the primary repair or graft (document primary CPT procedure), application and fixation of the tri-membrane wrap, and standard closure. Documentation should clearly link the add-on Q4344 charge to the primary procedure, record the area in square centimeters, and justify medical necessity (e.g., reinforcement of repair, coverage of critical structures, or prevention of adhesion). Typical sites of service are hospital inpatient, hospital outpatient department, or ambulatory surgical center. Typical patient scenarios include reconstruction after tumor resection with exposed tendon, revision Achilles repair requiring biological augmentation, or coverage of vascular grafts where additional membrane protection is indicated.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    15734Muscle, myocutaneous, or fasciocutaneous flap with microvascular anastomosis (free flap)Used when primary defect reconstruction is performed with a flap and the tri-membrane is applied as adjunctive coverage or reinforcement.
    15738Muscle, myocutaneous, or fasciocutaneous flap; with free flap with microvascular anastomosis, secondary proceduresRelated when additional flap revision requires membrane augmentation.
    49568Repair of initial incisional or ventral hernia; repair with mesh, openUsed in abdominal wall reconstruction where a biologic membrane is applied adjunctively to mesh placement.
    27427Ligamentous reconstruction (eg, multiple structures), knee; requiring graft (includes application of graft material)Performed when tendon or ligament repair requires biologic augmentation such as a tri-membrane wrap.
    24357Arthroplasty, elbow; with radial head excision and prosthetic implantationExample of an orthopedic primary procedure where adjunctive tri-membrane coverage may be applied to protect prosthetic or soft-tissue repairs.
    67840Repair of eyelid, full-thickness, including tarsal plate, with graft or flap; secondary repairIn periocular reconstructive cases, a tri-membrane may be used adjunctively to support delicate repairs.

    Related Modifiers

    9 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    54Modifier ‑54 (“Surgical care only”) is appended to a CPT surgical procedure when the reporting surgeon performs the intraoperative (surgical) component but does not furnish the preoperative and/or…- Use modifier -54 when the reporting surgeon provided only the intraoperative (surgical) component of a procedure and preoperative and/or postoperative management has been or will be provided by…
    55Modifier –55 indicates the billing provider furnished only postoperative management for a procedure that has a global surgical period. According to AAPC, this modifier is appended to the same CPT…- Use modifier -55 when billing the same CPT surgical code that has a 10- or 90-day global period and you, as a provider other than the original surgeon, furnished ONLY postoperative management (no…
    56Modifier ‑56 indicates the reporting provider furnished only the preoperative management for a surgical procedure and did not perform the intraoperative or postoperative care. It is used in…- Use Modifier -56 when a provider performs only the preoperative management in a split‑care situation (one physician manages preop care while a different physician performs the intraoperative…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…

    Related Provider Taxonomies

    8 rows

    Taxonomy CodeSpecialtyNotes
    207X00000XOrthopaedic Surgery PhysicianAn orthopaedic surgeon is trained in the preservation, investigation and restoration of the form and function of the extremities, spine and associated…
    208600000XSurgery PhysicianA general surgeon has expertise related to the diagnosis - preoperative, operative and postoperative management - and management of complications of s…
    208000000XPediatrics PhysicianA pediatrician is concerned with the physical, emotional and social health of children from birth to young adulthood. Care encompasses a broad spectru…
    363L00000XNurse Practitioner(1) A registered nurse provider with a graduate degree in nursing prepared for advanced practice involving independent and interdependent decision mak…
    208100000XPhysical Medicine & Rehabilitation PhysicianPhysical medicine and rehabilitation, also referred to as rehabilitation medicine, is the medical specialty concerned with diagnosing, evaluating, and…
    2278P4000XPatient Transport Certified Respiratory TherapistTransport respiratory therapist provide patient assessment, initiation of treatment modalities and continued monitoring of patient status of the criti…
    332BP3500XParenteral & Enteral Nutrition Supplies (DME)Suppliers · Durable Medical Equipment & Medical Supplies
    364SG0600XGerontology Clinical Nurse SpecialistPhysician Assistants & Advanced Practice Nursing Providers · Clinical Nurse Specialist

    Related ICD-10-CM Codes

    24 rows

    ICD-10-CM CodeDescription
    E10.621Type 1 diabetes mellitus with foot ulcer
    E11.621Type 2 diabetes mellitus with foot ulcer
    E11.65Type 2 diabetes mellitus with hyperglycemia
    I83.013Varicose veins of right lower extremity with ulcer of ankle
    I83.219Varicose veins of right lower extremity with both ulcer of unspecified site and inflammation
    I83.811Varicose veins of right lower extremity with pain
    I83.819Varicose veins of unspecified lower extremity with pain
    L89.101Pressure ulcer of unspecified part of back, stage 1
    L89.201Pressure ulcer of unspecified hip, stage 1
    L89.301Pressure ulcer of unspecified buttock, stage 1

    Showing 1–10 of 24

    Related Payer Policy Updates

    Specialty: Infectious Disease1 / 3

    10 rows

    PolicyPayerEffective Date
    B-Hemolytic Streptococcus TestingOscar Health2026-10-01
    Human Immunodeficiency Virus (HIV) — Coverage Criteria for Testing and Resistance AssaysOscar Health2026-10-01
    Hepatitis Testing (A, B, C, D) Coverage CriteriaOscar Health2026-10-01
    Lyme Disease Testing Coverage CriteriaOscar Health2026-10-01
    Pathogen Panel TestingOscar Health2026-10-01
    Diagnostic Testing of Common Sexually Transmitted InfectionsOscar Health2026-10-01
    Testing for Diagnosis of Active or Latent TuberculosisOscar Health2026-10-01
    Testing for Vector-Borne InfectionsOscar Health2026-10-01
    Coronavirus Testing in the Outpatient SettingOscar Health2026-10-01
    Human Immunodeficiency Virus (HIV)blue cross blue shield - louisiana2026-09-15

    Related Codes

    HCPCS-LEVEL-II-Q4139-INJECTABLE-AMNIOMATRIX-BIODMATRIX-1-CC

    HCPCS Q4139: Amniomatrix or Biodmatrix, Injectable, 1 cc

    HCPCS-LEVEL-II-Q4256-AREA-BASED-PROCEDURAL-ADD-ON-PER-SQ-CM

    HCPCS Q4256: MLG-complete Skin Graft Material, Per Sq Cm

    HCPCS-LEVEL-II-Q5132-ADALIMUMAB-AFZB-ABRILADA-10MG-INJECTION

    HCPCS Level II Q5132: Injection, adalimumab-afzb (Abrilada), 10 mg

    HCPCS-Q0035-CARDIOKYMOGRAPHY-CARDIAC-MOTION-RECORDING

    HCPCS Level II Q0035: Cardiokymography

    HCPCS-Q0081-INFUSION-THERAPY-NON-CHEMOTHERAPEUTIC-PER-VISIT

    HCPCS Level II Q0081: Infusion Therapy, Non‑Chemotherapeutic, Per Visit

    HCPCS-Q0083-CHEMOTHERAPY-NON-INFUSION-ADMINISTRATION

    HCPCS Q0083: Chemotherapy Administration, Non-Infusion Methods

    HCPCS-Q0084-CHEMOTHERAPY-INFUSION-ADMINISTRATION-PER-VISIT

    HCPCS Q0084: Chemotherapy Infusion Administration, Per Visit

    HCPCS-Q0085-CHEMOTHERAPY-INFUSION-PLUS-OTHER-TECHNIQUES-PER-VISIT

    HCPCS Q0085: Chemotherapy Infusion Plus Other Technique(s), Per Visit

    HCPCS-Q0091-PAP-SMEAR-SPECIMEN-COLLECTION-TRANSPORT

    HCPCS Q0091: Screening Papanicolaou Smear Collection and Transport

    HCPCS-Q0092-PORTABLE-XRAY-EQUIPMENT-SETUP

    HCPCS Q0092: Set-up Portable X-ray Equipment

    Showing 1–10 of 629

    • More pages

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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