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    v1.0.28
    OpenPayerBilling CodesPathology and Laboratory ServicesHCPCS hcpcs-p9073-platelets-pheresis-pathogen-reduced-unit
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    HCPCS P9073: Platelets, pheresis, pathogen-reduced, each unit

    HCPCS Level II code P9073 denotes a single unit of pheresis platelet product that has undergone pathogen reduction; the service is the provision of a pathogen-reduced platelet unit typically prepared in a blood bank or transfusion service and administered in an inpatient hospital, outpatient hospital, or ambulatory infusion/ transfusion center setting.

    For related coverage guidance, see recent payer policy updates: Epithelial Cell Cytology in Breast Cancer Risk Assessment, Chemotherapy Observation or Inpatient Hospitalization (for New Mexico Only), Umbilical Cord Blood Harvesting and Storage for Future Use (for Indiana Only).

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    • Billing CodesCPT, HCPCS, DRG & more
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    Clinical & Coding Specifications

    Clinical Context

    A typical patient receiving P9073 is an adult or pediatric inpatient or outpatient with thrombocytopenia or platelet dysfunction requiring transfusion support, such as a patient undergoing chemotherapy for hematologic malignancy, a patient with aplastic anemia, or a surgical patient with active bleeding and low platelet count. The blood bank supplies apheresis-derived, pathogen‑reduced platelet unit(s) to reduce infectious risk. Clinical workflow: the treating physician documents indication and obtains informed consent; laboratory verifies platelet count and orders transfusion; the transfusion service requests P9073 from blood bank inventory or external supplier; pre‑transfusion testing (type and screen, crossmatch if indicated) and patient identification checks are completed; the platelet unit is issued, transported under controlled conditions to the point of care; nursing administers transfusion while monitoring for reactions; post‑transfusion platelet count and clinical response are documented.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    36430Transfusion, therapeutic, plasma exchange; plasma exchange (plasmapheresis), requiring removal and replacement of plasmaNot directly the same as platelet transfusion but may be performed in patients requiring apheresis procedures or exchange therapies in hematologic conditions
    36460Therapeutic apheresis, not otherwise specifiedRelated to apheresis procedures; apheresis collection of platelets is upstream from distribution of apheresis platelet units
    99000Handling and/or special transportation of specimenMay apply to special handling/transport of blood products in some billing contexts (facility-specific)
    36415Collection of venous blood by venipuncturePerformed for pre‑transfusion type and screen testing prior to issuing P9073
    87070Culture, blood, aerobic and anaerobic; single or multipleUsed when evaluating suspected transfusion‑related infection, complementary to pathogen‑reduced product use

    Related Modifiers

    10 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    25CPT modifier 25 indicates that on the same day as another procedure or service, the same physician or other qualified health care professional provided a significant, separately identifiable…- When to apply: Use modifier 25 only on an E/M code to indicate the same provider delivered a significant, separately identifiable E/M service on the same day as another procedure or service — i.e.,…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
    90Modifier ‑90 (Reference/Outside Laboratory) indicates that a laboratory test was performed by an entity other than the treating or reporting provider. The American Medical Association defines…- Use CPT modifier -90 when a laboratory test is performed by an outside/reference laboratory (an entity other than the treating or reporting physician or qualified professional) and the claim needs…
    91Modifier 91 — “Repeat Clinical Diagnostic Laboratory Test” — is appended when the exact same CPT laboratory test is performed more than once for the same patient on the same day because serial,…- Use modifier 91 when the exact same CPT laboratory test is performed more than once on the same patient on the same date because serial or repeated testing is medically necessary to monitor…

    Related Provider Taxonomies

    8 rows

    Taxonomy CodeSpecialtyNotes
    207K00000XAllergy & Immunology PhysicianAn allergist-immunologist is trained in evaluation, physical and laboratory diagnosis, and management of disorders involving the immune system. Select…
    314000000XSkilled Nursing Facility(1) A skilled nursing facility is a facility or distinct part of an institution whose primary function is to provide medical, continuous nursing, and …
    363A00000XPhysician AssistantA physician assistant is a person who has successfully completed an accredited education program for physician assistant, is licensed by the state and…
    207XS0114XAdult Reconstructive Orthopaedic Surgery PhysicianRecognized by several state medical boards as a fellowship subspecialty program of orthopaedic surgery, adult reconstructive orthopaedic surgeons deal…
    2471S1302XSonography Radiologic TechnologistA radiologic technologist who specializes in sonography and is appropriately educated and trained, consistent with nationally recognized standards, st…
    103TP0814XPsychoanalysis PsychologistA psychologist whose specialty is distinguished from other specialties by its body of knowledge and its intensive treatment approaches. It aims at str…
    242T00000XPerfusionistA perfusionist operates extracorporeal circulation and autotransfusion equipment during any medical situation where it is necessary to support or temp…
    335V00000XPortable X-ray and/or Other Portable Diagnostic Imaging SupplierA supplier that provides one or more of the following portable services, including but not limited to, x-ray, electrocardiogram (EKG), long-term EKG (…

    Related ICD-10-CM Codes

    26 rows

    ICD-10-CM CodeDescription
    C85.90Non-Hodgkin lymphoma, unspecified, unspecified site
    C92.00Acute myeloblastic leukemia, not having achieved remission
    C92.10Chronic myeloid leukemia, BCR/ABL-positive, not having achieved remission
    C95.10Chronic leukemia of unspecified cell type not having achieved remission
    C95.90Leukemia, unspecified not having achieved remission
    D47.3Essential (hemorrhagic) thrombocythemia
    D61.810Antineoplastic chemotherapy induced pancytopenia
    D61.9Aplastic anemia, unspecified
    D64.9Anemia, unspecified
    D69.0Allergic purpura

    Showing 1–10 of 26

    Related Payer Policy Updates

    Specialty: Hematology/Oncology1 / 4

    10 rows

    PolicyPayerEffective Date
    Epithelial Cell Cytology in Breast Cancer Risk AssessmentOscar Health2026-10-01
    Chemotherapy Observation or Inpatient Hospitalization (for New Mexico Only)UnitedHealthcare2026-08-01
    Umbilical Cord Blood Harvesting and Storage for Future Use (for Indiana Only)UnitedHealthcare2026-08-01
    Antibody-Drug ConjugatesPremera Bluecross2026-08-01
    Chimeric Antigen Receptor (CAR) T-Cell TherapyColorado Rocky Mountain Health Plans2026-08-01
    Allogeneic Hematopoietic Progenitor Cell TherapyAmbetter Georgia2026-08-01
    Umbilical Cord Blood Harvesting and Storage for Future Use (for Idaho Only)UnitedHealthcare2026-08-01
    Umbilical Cord Blood Harvesting and Storage for Future Use (for New Jersey Only)UnitedHealthcare2026-08-01
    Umbilical Cord Blood Harvesting and Storage for Future Use (for Ohio Only)UnitedHealthcare2026-08-01
    Reblozyl (luspatercept-aamt) Medical Benefit Drug PolicyUnitedHealthcare2026-08-01

    Related Codes

    HCPCS-LEVEL-II-P2029-CONGO-RED-BLOOD-TEST

    HCPCS P2029: Congo red, blood

    HCPCS-P2028-CEPHALIN-FLOCCULATION-BLOOD

    HCPCS Level II P2028: Cephalin Flocculation, Blood

    HCPCS-P2031-HAIR-ANALYSIS-EXCLUDING-ARSENIC

    HCPCS P2031: Hair Analysis (Excluding Arsenic)

    HCPCS-P2033-THYMOL-TURBIDITY-BLOOD-LAB-TEST

    HCPCS P2033: Thymol Turbidity, Blood

    HCPCS-P2038-MUCOPROTEIN-BLOOD-SEROMUCOID-LAB-TEST

    HCPCS Level II P2038: Mucoprotein (Seromucoid) Blood Test

    HCPCS-P3000-SCREENING-PAP-SMEAR-TECHNICIAN-SUPERVISED

    HCPCS Level II P3000: Screening Papanicolaou Smear by Technician

    HCPCS-P3001-SCREENING-PAP-SMEAR-CERVICAL-VAGINAL

    HCPCS Level II P3001: Screening Papanicolaou Smear, Up to Three Smears

    HCPCS-P7001-QUANTITATIVE-URINE-BACTERIAL-CULTURE-SENSITIVITY

    HCPCS P7001: Urine Bacterial Culture, Quantitative with Sensitivity

    HCPCS-P9010-WHOLE-BLOOD-TRANSFUSION-PER-UNIT

    HCPCS Level II P9010: Blood (whole) for Transfusion, per Unit

    HCPCS-P9011-BLOOD-SPLIT-UNIT

    HCPCS Level II P9011: Blood, Split Unit

    Showing 1–10 of 58

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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