HCPCS P9070: Pooled Pathogen-Reduced Frozen Plasma, Per Unit - OpenPayer

Summary & Overview

HCPCS P9070: Pooled Pathogen-Reduced Frozen Plasma, Per Unit

HCPCS Level II code P9070 denotes a unit of pooled, pathogen-reduced frozen plasma. Plasma products with pathogen reduction are increasingly used to lower transfusion-transmitted infection risks and are relevant across hospital and transfusion service workflows. This code matters nationally because it standardizes billing for a specialized plasma product that may have different supply, storage, and clinical-use considerations compared with single-donor plasma.

Key payers addressed in this analysis include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find a concise overview of clinical context for pathogen-reduced pooled plasma, typical sites of service where the product is used, and the payers commonly covering these items. The publication also summarizes billing benchmarks, coverage considerations, and notable policy updates affecting reimbursement coding and use of pathogen-reduced plasma.

This summary equips revenue cycle, clinical, and policy stakeholders with the core facts about P9070, how it fits into transfusion service operations, and the payer landscape for coverage and claims reporting at a national level.

AetnaBlue Cross Blue ShieldCigna HealthUnitedHealthcareMedicareP9070HCPCS Level IIplasmapathogen reductionblood productstransfusionhospitalblood bank

Billing Code Overview

HCPCS Level II code P9070 describes plasma, pooled multiple donor, pathogen reduced, frozen, each unit. This code represents supply of biologic plasma that has been collected from multiple donors, processed with pathogen-reduction methods, frozen, and dispensed as an individual unit.

Service type: Blood product transfusion supply (therapeutic or replacement plasma unit)
Typical site of service: Hospital inpatient and outpatient settings, blood banks, transfusion centers, and other clinical settings where plasma products are administered or stored for transfusion

Clinical & Coding Specifications

Clinical Context

A hospitalized adult patient with traumatic hemorrhage or a coagulopathy following massive transfusion requires plasma replacement. The blood bank issues P9070 (plasma, pooled multiple donor, pathogen reduced, frozen, each unit) to restore clotting factors after thawing and transfusion. Typical workflow: clinician documents indication (e.g., acute major bleeding, reversal of warfarin in life‑threatening hemorrhage, disseminated intravascular coagulation), orders replacement plasma in the electronic medical record, and places a blood bank request specifying product attributes (pooled, pathogen‑reduced). The transfusion service crossmatches/compatibility checks, thaws the frozen units per institutional protocol, and delivers units to the floor or operating room. Nursing verifies patient identity, obtains informed consent per institutional policy, monitors vital signs and transfusion reactions during and after infusion, and documents volume and unit identifiers in the medical record. Common settings include inpatient acute care wards, operating rooms, and emergency departments. Typical patients are perioperative trauma patients, patients with massive transfusion protocols activated, or patients with severe coagulopathy requiring plasma factor replacement.

Coding Specifications

Modifier	Description	When to Use
`00`	No modifier — standard reporting	Use when no additional modifier is required; report the base HCPCS code as billed for a complete, routine unit.

Related Codes

HCPCS-P9047-ALBUMIN-25-50ML-INFUSION

HCPCS P9047: Infusion of Human Albumin 25%, 50 ml

HCPCS-P3001-SCREENING-PAP-SMEAR-CERVICAL-VAGINAL

HCPCS P3001: Screening Papanicolaou Smear, Cervical or Vaginal

HCPCS-P9039-RED-BLOOD-CELLS-DEGLYCEROLIZED-UNIT

HCPCS P9039: Red Blood Cells, Deglycerolized, Each Unit

HCPCS-P9040-RED-BLOOD-CELLS-LEUKOCYTES-REDUCED-IRRADIATED-UNIT

HCPCS P9040: Red Blood Cells, Leukocytes Reduced, Irradiated, Each Unit

HCPCS-P9041-ALBUMIN-5PCT-50ML-INFUSION

HCPCS P9041: Infusion of Albumin (Human) 5% 50 ml

HCPCS-P9055-APHERESIS-PLATELETS-LEUKOCYTE-REDUCED-CMV-NEGATIVE

HCPCS Level II P9055: Apheresis Platelets, Leukocyte-Reduced, CMV-Negative

HCPCS-P9100-PLATELET-PATHOGEN-TEST

HCPCS P9100: Platelet Pathogen(s) Test

HCPCS-P9052-HLA-MATCHED-LEUKOCYTE-REDUCED-PLATELET-UNIT-APHERESIS

HCPCS P9052: HLA-Matched, Leukocyte-Reduced Platelet Unit (Apheresis)

HCPCS-P9057-FROZEN-DEGLYCEROLIZED-WASHED-RBC-LEUKOCYTE-REDUCED-IRRADIATED

HCPCS P9057: Frozen/Deglycerolized/Washed, Leukocyte-Reduced, Irradiated RBC Unit

HCPCS-P9615-CATHETERIZATION-SPECIMEN-COLLECTION-MULTIPLE-PATIENTS

HCPCS P9615: Catheterization for Collection of Specimen(s), Multiple Patients

Showing 1–10 of 58

Taxonomy Code	Specialty	Notes
`208D00000X`	Hematology	Physicians who manage transfusion decisions, coagulopathy, and blood product utilization.
`207K00000X`	Transfusion Medicine (Pathology)	Pathologists and transfusion medicine specialists overseeing blood bank operations and product selection.
`2084P0800X`	Critical Care Medicine	Intensivists ordering plasma for massive transfusion or coagulopathy in critically ill patients.
`207L00000X`	Anesthesiology	Anesthesiologists coordinating intraoperative transfusion for bleeding control.
`163W00000X`	Emergency Medicine	Emergency physicians initiating massive transfusion and ordering plasma in the ED.

Related Diagnoses

ICD-10 Code	Description	Clinical Relevance
`D68.32`	Acquired coagulation factor deficiency	Indicates a need for factor replacement with plasma when specific concentrates are not available.
`D68.4`	Acquired coagulation factor inhibitors	May require plasma or alternative products to manage bleeding due to inhibitors.
`D62`	Acute posthemorrhagic anemia	Associated with significant blood loss where plasma may be used as part of massive transfusion protocols.
`O72.2`	Postpartum hemorrhage, other and unspecified	Severe obstetric bleeding where plasma is commonly used in resuscitation.
`T80.6XXA`	Infection following infusion, initial encounter	Relevant as a diagnosis to track transfusion reactions or complications (monitoring and documentation).
`R58`	Hemorrhage, not elsewhere classified	General acute bleeding indication where plasma may be indicated to correct coagulopathy.
`D65`	Disseminated intravascular coagulation (DIC)	Classic indication for plasma to replace consumed clotting factors in DIC management.
`Z92.82`	Personal history of transfusion reaction	Important for transfusion planning; may influence product selection such as pathogen‑reduced pooled plasma.

Related CPT Codes

CPT Code	Description	Relationship to This Procedure
`36415`	Collection of venous blood by venipuncture	Performed prior to transfusion for baseline labs, crossmatch, and compatibility testing.
`36430`	Transfusion, blood product administration (peripheral or central line), single or multiple products, lavage and/or infusion	CPT for the actual administration of blood products; documents nursing/infusion service for the plasma transfusion event.
`85025`	Blood count; complete (CBC) with automated differential WBC count	Common laboratory test before/after transfusion to assess hemoglobin and response to blood product therapy.
`86140`	Antibody screen, each patient	Used by the blood bank to screen recipient antibodies prior to crossmatch and issuing plasma units.
`86850`	Crossmatch; recipient and donor blood by serologic test (major and minor)	Performed in transfusion compatibility testing before issuing plasma in certain circumstances.