HCPCS Level II J9176: Injection, elotuzumab, 1 mg

HCPCS Level II code J9176 describes the drug supply for an injection of elotuzumab, billed per 1 mg; the service represents administration of a monoclonal antibody oncology medication and is typically reported when the drug is provided for infusion or injection in an outpatient infusion center or hospital outpatient department setting.

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HCPCS Level II J9176: Injection, elotuzumab, 1 mg

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Get alerted when payer policies referencing J9176 are released or updated.

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Clinical & Coding Specifications

Clinical Context

A typical patient is an adult with relapsed or refractory multiple myeloma who is a candidate for immunotherapy with elotuzumab. The patient presents to an outpatient infusion center or hospital outpatient department for intravenous administration of J9176 (elotuzumab) dosed per provider orders. Prior to infusion, oncology nursing performs medication verification, allergy check, baseline vital signs, and premedication orders (antipyretic, antihistamine, corticosteroid) as indicated. An indwelling peripheral IV or central venous access device is used depending on venous access and therapy plan. The infusion is administered by an oncology-certified infusion nurse with monitoring for infusion reactions; vital signs are recorded at baseline, periodically during infusion, and post-infusion. The encounter includes documentation of diagnosis(es) justifying therapy, medication lot and NDC verification, infusion start/stop times, any reactions and interventions, and instructions for follow-up oncology visits and laboratory monitoring (CBC, CMP). Typical sites of service are outpatient oncology infusion centers, hospital outpatient departments, and occasionally skilled nursing facilities with appropriate oncology infusion capabilities.

Related CPT Codes

CPT Code	Description	Relationship to This Procedure
`96413`	Chemotherapy administration, intravenous infusion technique; initiation of infusion up to 1 hour, single or initial substance/drug	Used when initiating an IV infusion of a chemotherapy or biologic agent such as elotuzumab for up to 1 hour
`96415`	Chemotherapy administration, each additional hour (list separately in addition to code for primary infusion)	Billed for each additional hour of infusion time when elotuzumab infusion exceeds the initial hour
`96417`	Chemotherapy administration, additional sequential infusion, same agent/line (per hour)	Used when multiple-hour continuous infusions require add-on billing (apply per payer rules)
`96365`	Intravenous infusion, initial, up to 1 hour, therapeutic, prophylactic, or diagnostic; other than chemotherapy	Occasionally used for non-chemotherapy biologic infusions in facility settings depending on payer policy
`99070`	Supplies and material (e.g., saline flushes, IV tubing)	Billed for non-covered supplies used in the administration of `J9176` per facility or payer guidelines

Related Modifiers

5 rows

Modifier	Description	When to Use
22	Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…	- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
52	Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…	- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
53	Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…	- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
76	Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…	- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
78	CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…	- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…

Related Provider Taxonomies

8 rows

Taxonomy Code	Specialty	Notes
208000000X	Pediatrics Physician	A pediatrician is concerned with the physical, emotional and social health of children from birth to young adulthood. Care encompasses a broad spectru…
207RC0000X	Cardiovascular Disease Physician	An internist who specializes in diseases of the heart and blood vessels and manages complex cardiac conditions such as heart attacks and life-threaten…
363A00000X	Physician Assistant	A physician assistant is a person who has successfully completed an accredited education program for physician assistant, is licensed by the state and…
363L00000X	Nurse Practitioner	(1) A registered nurse provider with a graduate degree in nursing prepared for advanced practice involving independent and interdependent decision mak…
174400000X	Specialist	An individual educated and trained in an applied knowledge discipline used in the performance of work at a level requiring knowledge and skills beyond…
282E00000X	Long Term Care Hospital	Long-term care hospitals (LTCHs) furnish extended medical and rehabilitative care to individuals who are clinically complex and have multiple acute or…
246QH0600X	Histology Specialist/Technologist	Technologists, Technicians & Other Technical Service Providers · Specialist/Technologist, Pathology
311ZA0620X	Adult Care Home Facility	A custodial care facility providing supportive and personal care services to disabled and/or elderly individuals who cannot function independently in …

Related Codes

HCPCS-J9000-DOXORUBICIN-10MG-INJECTION

HCPCS J9000: Doxorubicin Hydrochloride Injection, 10 mg

HCPCS-J9003-LEUPROLIDE-INJECTABLE-CAMCEVI-1MG

HCPCS Level II J9003: Leuprolide injectable (camcevi etm), 1 mg

HCPCS-J9010-ALEMTUZUMAB-INJECTION-10MG

HCPCS Level II J9010: Injection, alemtuzumab, 10 mg

HCPCS-J9011-DATOPOTAMAB-DERUXTECAN-INJECTION-1MG

HCPCS J9011: Datopotamab Deruxtecan Injection, 1 mg

HCPCS-J9015-ALDESLEUKIN-INJECTION-SINGLE-USE-VIAL

HCPCS Level II J9015: Aldesleukin Injection, Single-Use Vial

HCPCS-J9017-ARSENIC-TRIOXIDE-INJECTION-1MG

HCPCS J9017: Arsenic Trioxide Injection, 1 mg

HCPCS-J9019-ASPARAGINASE-ERWINAZE-INJECTION-1000-IU

HCPCS Level II J9019: Asparaginase (Erwinaze) Injection, 1,000 IU

HCPCS-J9020-ASPARAGINASE-INJECTION-10000-UNITS

HCPCS J9020: Asparaginase Injection, 10,000 Units

HCPCS-J9021-ASPARAGINASE-RYLAZE-INJECTION-0-1-MG

HCPCS Level II J9021: Injection, asparaginase (Rylaze), 0.1 mg

HCPCS-J9022-ATEZOLIZUMAB-INJECTION-10MG

HCPCS J9022: Injection, atezolizumab 10 mg

Showing 1–10 of 227

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

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Clinical & Coding Specifications

Clinical Context

Related CPT Codes

CPT Code	Description	Relationship to This Procedure
`96413`	Chemotherapy administration, intravenous infusion technique; initiation of infusion up to 1 hour, single or initial substance/drug	Used when initiating an IV infusion of a chemotherapy or biologic agent such as elotuzumab for up to 1 hour
`96415`	Chemotherapy administration, each additional hour (list separately in addition to code for primary infusion)	Billed for each additional hour of infusion time when elotuzumab infusion exceeds the initial hour
`96417`	Chemotherapy administration, additional sequential infusion, same agent/line (per hour)	Used when multiple-hour continuous infusions require add-on billing (apply per payer rules)
`96365`	Intravenous infusion, initial, up to 1 hour, therapeutic, prophylactic, or diagnostic; other than chemotherapy	Occasionally used for non-chemotherapy biologic infusions in facility settings depending on payer policy
`99070`	Supplies and material (e.g., saline flushes, IV tubing)	Billed for non-covered supplies used in the administration of `J9176` per facility or payer guidelines

Related Modifiers

5 rows

Modifier	Description	When to Use
22	Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…	- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
52	Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…	- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
53	Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…	- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
76	Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…	- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
78	CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…	- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…

Related Provider Taxonomies

8 rows

Taxonomy Code	Specialty	Notes
208000000X	Pediatrics Physician	A pediatrician is concerned with the physical, emotional and social health of children from birth to young adulthood. Care encompasses a broad spectru…
207RC0000X	Cardiovascular Disease Physician	An internist who specializes in diseases of the heart and blood vessels and manages complex cardiac conditions such as heart attacks and life-threaten…
363A00000X	Physician Assistant	A physician assistant is a person who has successfully completed an accredited education program for physician assistant, is licensed by the state and…
363L00000X	Nurse Practitioner	(1) A registered nurse provider with a graduate degree in nursing prepared for advanced practice involving independent and interdependent decision mak…
174400000X	Specialist	An individual educated and trained in an applied knowledge discipline used in the performance of work at a level requiring knowledge and skills beyond…
282E00000X	Long Term Care Hospital	Long-term care hospitals (LTCHs) furnish extended medical and rehabilitative care to individuals who are clinically complex and have multiple acute or…
246QH0600X	Histology Specialist/Technologist	Technologists, Technicians & Other Technical Service Providers · Specialist/Technologist, Pathology
311ZA0620X	Adult Care Home Facility	A custodial care facility providing supportive and personal care services to disabled and/or elderly individuals who cannot function independently in …

Related Codes

HCPCS-J9000-DOXORUBICIN-10MG-INJECTION

HCPCS J9000: Doxorubicin Hydrochloride Injection, 10 mg

HCPCS-J9003-LEUPROLIDE-INJECTABLE-CAMCEVI-1MG

HCPCS Level II J9003: Leuprolide injectable (camcevi etm), 1 mg

HCPCS-J9010-ALEMTUZUMAB-INJECTION-10MG

HCPCS Level II J9010: Injection, alemtuzumab, 10 mg

HCPCS-J9011-DATOPOTAMAB-DERUXTECAN-INJECTION-1MG

HCPCS J9011: Datopotamab Deruxtecan Injection, 1 mg

HCPCS-J9015-ALDESLEUKIN-INJECTION-SINGLE-USE-VIAL

HCPCS Level II J9015: Aldesleukin Injection, Single-Use Vial

HCPCS-J9017-ARSENIC-TRIOXIDE-INJECTION-1MG

HCPCS J9017: Arsenic Trioxide Injection, 1 mg

HCPCS-J9019-ASPARAGINASE-ERWINAZE-INJECTION-1000-IU

HCPCS Level II J9019: Asparaginase (Erwinaze) Injection, 1,000 IU

HCPCS-J9020-ASPARAGINASE-INJECTION-10000-UNITS

HCPCS J9020: Asparaginase Injection, 10,000 Units

HCPCS-J9021-ASPARAGINASE-RYLAZE-INJECTION-0-1-MG

HCPCS Level II J9021: Injection, asparaginase (Rylaze), 0.1 mg

HCPCS-J9022-ATEZOLIZUMAB-INJECTION-10MG

HCPCS J9022: Injection, atezolizumab 10 mg

Showing 1–10 of 227

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

HCPCS Level II J9176: Injection, elotuzumab, 1 mg

Sign up for hcpcs J9176 policy alerts

HCPCS Level II J9176: Injection, elotuzumab, 1 mg

Sign up for hcpcs J9176 policy alerts

Clinical & Coding Specifications

Clinical Context

Related CPT Codes

Related Modifiers

Related Provider Taxonomies

Related Codes

What does HCPCS code J9176 represent and where is it typically used?

What clinical and documentation elements should accompany a J9176 claim?

Which administration and supply CPT codes are commonly billed with J9176?

Which modifiers are applicable when billing J9176 and when are they used?

Which payers are covered in the analysis and does the page provide payer‑specific reimbursement rates?

References

Clinical & Coding Specifications

Clinical Context

Related CPT Codes

Related Modifiers

Related Provider Taxonomies

Related Codes

What does HCPCS code J9176 represent and where is it typically used?

What clinical and documentation elements should accompany a J9176 claim?

Which administration and supply CPT codes are commonly billed with J9176?

Which modifiers are applicable when billing J9176 and when are they used?

Which payers are covered in the analysis and does the page provide payer‑specific reimbursement rates?

References