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    v1.0.28
    OpenPayerBilling CodesDrugs Administered Other than Oral MethodHCPCS hcpcs-j3010-fentanyl-citrate-injection-0-1-mg
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    HCPCS Level II J3010: Injection, fentanyl citrate, 0.1 mg

    HCPCS Level II code J3010 describes the drug supply for an injection of fentanyl citrate, 0.1 mg, intended for parenteral administration as an opioid analgesic injection used in settings such as hospital inpatient, outpatient, emergency department, or clinic depending on clinical need; the code represents the medication component for billing when the 0.1 mg fentanyl citrate dose is supplied for injection.

    For related coverage guidance, see recent payer policy updates: Epithelial Cell Cytology in Breast Cancer Risk Assessment, Chemotherapy Observation or Inpatient Hospitalization (for New Mexico Only), Umbilical Cord Blood Harvesting and Storage for Future Use (for Indiana Only).

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    Table of contents

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    • Billing CodesCPT, HCPCS, DRG & more
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    Clinical & Coding Specifications

    Clinical Context

    A patient presents to an outpatient surgical center or hospital procedural unit requiring procedural analgesia or anesthesia for a painful intervention. Typical scenarios include short, painful procedures such as wound debridement, burn care, dental extraction in a medically complex patient, or anesthesia adjunct for minor surgical procedures. The medication is supplied as J3010 (Injection, fentanyl citrate, 0.1 mg) and is administered intravenously by a licensed clinician (anesthesiologist, nurse anesthetist, or intensivist) as part of monitored anesthesia care (MAC) or general anesthesia.

    A typical workflow: the patient arrives for the scheduled procedure; pre-procedure assessment documents indication, allergies, airway evaluation, and concurrent medications. Standard monitoring (pulse oximetry, blood pressure, ECG, capnography if sedated) is applied. A clinician draws and doses the fentanyl citrate according to weight and clinical needs; documentation records the drug name, J3010 billing unit(s), dose administered, route (intravenous), time, and administering clinician. Post-procedure recovery includes monitoring for respiratory depression, sedation level, and pain control before discharge or transfer to an inpatient bed. Billing uses J3010 with appropriate units and may add modifiers per payer rules to indicate aspects such as professional service, NCCI-related circumstances, or provider specialty.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    00320Anesthesia for procedures on the integumentary system on the extremities (e.g., burns, debridement)Often billed for anesthesia services when J3010 is used as part of general or regional anesthesia for wound care or debridement
    00562Anesthesia for lower intestinal tract procedures (e.g., colonoscopy)Fentanyl may be administered as part of monitored anesthesia care or general anesthesia for endoscopic procedures covered by this anesthesia code
    00740Anesthesia for upper urinary tract procedures (e.g., cystoscopy)Commonly used when fentanyl is given as adjunct analgesia during urologic procedures
    00840Anesthesia for procedures on the pelvis (e.g., minor gynecologic procedures)Fentanyl administration supports analgesia during gynecologic operative or diagnostic procedures
    99152Moderate sedation services (initial 15 minutes intra-service time)When procedural sedation is used instead of general anesthesia, fentanyl J3010 may be administered and reported alongside moderate sedation codes
    96372Therapeutic, prophylactic, or diagnostic injection (e.g., medication administration)When an injection administration service is billed in addition to the drug supply (per payer rules), this code may appear in the workflow

    Related Modifiers

    7 rows

    ModifierDescriptionWhen to Use
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    25CPT modifier 25 indicates that on the same day as another procedure or service, the same physician or other qualified health care professional provided a significant, separately identifiable…- When to apply: Use modifier 25 only on an E/M code to indicate the same provider delivered a significant, separately identifiable E/M service on the same day as another procedure or service — i.e.,…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    91Modifier 91 — “Repeat Clinical Diagnostic Laboratory Test” — is appended when the exact same CPT laboratory test is performed more than once for the same patient on the same day because serial,…- Use modifier 91 when the exact same CPT laboratory test is performed more than once on the same patient on the same date because serial or repeated testing is medically necessary to monitor…

    Related Provider Taxonomies

    8 rows

    Taxonomy CodeSpecialtyNotes
    2084P0800XPsychiatry PhysicianA Psychiatrist specializes in the prevention, diagnosis, and treatment of mental disorders, emotional disorders, psychotic disorders, mood disorders, …
    367A00000XAdvanced Practice MidwifeAdvanced practice midwifery encompasses the independent provision of care during pregnancy, childbirth, and the postpartum period; sexual and reproduc…
    363L00000XNurse Practitioner(1) A registered nurse provider with a graduate degree in nursing prepared for advanced practice involving independent and interdependent decision mak…
    176B00000XMidwifeA Midwife is a trained professional with special expertise in supporting women to maintain a healthy pregnancy birth, offering expert individualized c…
    1223G0001XGeneral Practice DentistryA general dentist is the primary dental care provider for patients of all ages. The general dentist is responsible for the diagnosis, treatment, manag…
    111NX0100XOccupational Health ChiropractorOccupational Health is that specialty within the chiropractic profession that deals with the prevention and management of work related injuries. It al…
    207Q00000XFamily Medicine PhysicianFamily Medicine is the medical specialty which is concerned with the total health care of the individual and the family. It is the specialty in breadt…
    163WX0601XOtorhinolaryngology & Head-Neck Registered NurseNursing Service Providers · Registered Nurse

    Related ICD-10-CM Codes

    24 rows

    ICD-10-CM CodeDescription
    C79.51Secondary malignant neoplasm of bone
    G43.909Migraine, unspecified, not intractable, without status migrainosus
    G44.1Vascular headache, not elsewhere classified
    G44.209Tension-type headache, unspecified, not intractable
    G89.3Neoplasm related pain (acute) (chronic)
    G89.4Chronic pain syndrome
    M17.11Unilateral primary osteoarthritis, right knee
    M19.071Primary osteoarthritis, right ankle and foot
    M25.50Pain in unspecified joint
    M25.561Pain in right knee

    Showing 1–10 of 24

    Related Payer Policy Updates

    Specialty: Hematology/Oncology1 / 3

    10 rows

    PolicyPayerEffective Date
    Epithelial Cell Cytology in Breast Cancer Risk AssessmentOscar Health2026-10-01
    Chemotherapy Observation or Inpatient Hospitalization (for New Mexico Only)UnitedHealthcare2026-08-01
    Umbilical Cord Blood Harvesting and Storage for Future Use (for Indiana Only)UnitedHealthcare2026-08-01
    Antibody-Drug ConjugatesPremera Bluecross2026-08-01
    Chimeric Antigen Receptor (CAR) T-Cell TherapyColorado Rocky Mountain Health Plans2026-08-01
    Allogeneic Hematopoietic Progenitor Cell TherapyAmbetter Georgia2026-08-01
    Umbilical Cord Blood Harvesting and Storage for Future Use (for Idaho Only)UnitedHealthcare2026-08-01
    Umbilical Cord Blood Harvesting and Storage for Future Use (for New Jersey Only)UnitedHealthcare2026-08-01
    Umbilical Cord Blood Harvesting and Storage for Future Use (for Ohio Only)UnitedHealthcare2026-08-01
    Reblozyl (luspatercept-aamt) Medical Benefit Drug PolicyUnitedHealthcare2026-08-01

    Related Codes

    HCPCS-J0013-ESKETAMINE-NASAL-SPRAY-1MG

    HCPCS Level II J0013: Esketamine Nasal Spray, 1 mg

    HCPCS-J0120-INJECTION-TETRACYCLINE-250MG

    HCPCS Level II J0120: Injection, Tetracycline, up to 250 mg

    HCPCS-J0121-OMADACYCLINE-INJECTION-1MG

    HCPCS Level II J0121: Omadacycline Injection, 1 mg

    HCPCS-J0122-ERAVACYCLINE-INJECTION-1MG

    HCPCS Level II J0122: Injection, eravacycline, 1 mg

    HCPCS-J0129-ABATACEPT-INJECTION-10MG-PHYSICIAN-SUPERVISED

    HCPCS Level II J0129: Abatacept Injection, 10 mg

    HCPCS-J0130-INJECTION-ABCIXIMAB-10MG

    HCPCS Level II J0130: Injection abciximab, 10 mg

    HCPCS-J0131-INJECTION-ACETAMINOPHEN-10MG-PARENTERAL-ANALGESIC

    HCPCS Level II J0131: Injection, Acetaminophen 10 mg

    HCPCS-J0132-INJECTION-ACETYLCYSTEINE-100MG-INJECTABLE-MEDICATION

    HCPCS Level II J0132: Injection, Acetylcysteine 100 mg

    HCPCS-J0133-ACYCLOVIR-INJECTION-5MG

    HCPCS Level II J0133: Injection, Acyclovir 5 mg

    HCPCS-J0134-ACETAMINOPHEN-INJECTION-FRESENIUS-KABI-10MG

    HCPCS Level II J0134: Injection, Acetaminophen (10 mg)

    Showing 1–10 of 991

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    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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