Summary & Overview
HCPCS J3000: Injection, Streptomycin Up to 1 gm
HCPCS Level II code J3000 denotes the injectable administration of streptomycin up to 1 gram. This code is used to bill for a single therapeutic dose of the antibiotic when administered parenterally. Nationally, accurate coding for injectable antibiotics like streptomycin is important for clinical documentation, pharmacy oversight, and payer adjudication due to potential safety monitoring and drug-specific coverage rules.
Key payers included in this analysis are Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find clinical context for when J3000 is used, common sites of service where the injection is administered, and an overview of billing considerations that influence reimbursement and claim processing. The publication summarizes expected benchmarks, notes on payer coverage patterns, and any relevant policy or coding updates affecting injectable antibiotic claims.
This summary is intended to support clinical coders, billing staff, pharmacy administrators, and policy analysts who need a concise reference for HCPCS Level II code J3000 and its role in outpatient and hospital-based drug administration workflows.
Billing Code Overview
HCPCS Level II code J3000 describes an injection of streptomycin, up to 1 gram. This code represents a single administration of the antibiotic streptomycin by injection. The service type is therapeutic drug administration (injectable antibiotic). The typical site of service is outpatient clinic, physician office, or hospital outpatient department where parenteral antibiotics are administered.
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Clinical & Coding Specifications
Clinical Context
A typical patient receiving J3000 (Injection, streptomycin, up to 1 gm) is an adult or pediatric patient being treated for a streptomycin‑sensitive mycobacterial infection or certain gram‑negative infections when streptomycin is indicated. The patient may present to an outpatient infectious disease clinic, hospital inpatient ward, public health clinic, or specialty tuberculosis (TB) treatment center.
A realistic scenario: a 45‑year‑old patient with confirmed pulmonary tuberculosis caused by a streptomycin‑sensitive Mycobacterium tuberculosis strain requires intramuscular streptomycin as part of a multi‑drug regimen. The clinical workflow includes: initial infectious disease or public health evaluation, laboratory confirmation and sensitivity testing, order entry for J3000 with dose verification, informed consent and allergy check, preparation of streptomycin for intramuscular administration (typically gluteal or vastus lateralis), site antisepsis, injection by an authorized clinician (e.g., physician, nurse, or public health clinician), post‑injection observation for adverse reactions (ototoxicity, nephrotoxicity, allergic reaction), documentation of lot number and units administered, and scheduling of follow‑up visits with audiometry and renal function monitoring as clinically indicated.
Coding Specifications
| Modifier | Description | When to Use |
|---|---|---|
00 |