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    v1.0.28
    OpenPayerBilling CodesDrugs Administered Other than Oral MethodHCPCS hcpcs-j2920-methylprednisolone-injection-up-to-40-mg
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    HCPCS Level II J2920: Methylprednisolone Injection, up to 40 mg

    HCPCS Level II code J2920 denotes an injection of methylprednisolone sodium succinate up to 40 mg, a short-acting systemic corticosteroid formulation typically administered as an intramuscular or intravenous injection in outpatient clinics, physician offices, or hospital outpatient departments for anti-inflammatory and immunosuppressive indications; this billing code is used to report the specific drug and dose delivered when documenting medication administration and preparing professional or facility claims for the injectable corticosteroid service.

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    • Billing CodesCPT, HCPCS, DRG & more
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    Clinical & Coding Specifications

    Clinical Context

    A 58-year-old patient with a history of chronic lumbar radiculopathy and episodic inflammatory flares presents to an outpatient ambulatory infusion suite for an intramuscular or intra-articular corticosteroid injection. The clinician documents focal pain, reduced range of motion, and a trial of conservative therapies (NSAIDs, physical therapy) with inadequate relief. After informed consent, the provider prepares methylprednisolone sodium succinate up to 40 mg for administration. Typical workflow: pre-procedure assessment (vitals, allergy review, anticoagulation status), site preparation and optional local anesthetic, administration of the injection (intramuscular, intra-articular, or periarticular), post-procedure monitoring for immediate adverse reaction, and brief discharge instructions. The service commonly occurs in an outpatient clinic, physician office, ambulatory surgery center, or outpatient infusion center.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    20610Arthrocentesis, aspiration and/or injection, major joint or bursa (e.g., shoulder, hip, knee)Commonly performed when delivering intra-articular methylprednisolone to treat joint inflammation; may include aspiration prior to injection.
    20605Arthrocentesis, aspiration and/or injection, intermediate joint or bursa (e.g., elbow, ankle)Used for injections into intermediate-sized joints when treating localized inflammatory conditions.
    20550Injection(s); single tendon sheath, or ligament, aponeurosis (e.g., trigger finger)Applies when corticosteroid is injected into a tendon sheath or small soft-tissue structure.
    96372Therapeutic, prophylactic, or diagnostic injection (specify substance or drug); subcutaneous or intramuscularUsed when methylprednisolone is given as an intramuscular injection in an office or clinic setting.
    77002Fluoroscopic guidance for needle placement (e.g., spine, joint)Used when image guidance is required to place the needle accurately for intra-articular or perineural steroid injection.

    Related Modifiers

    6 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…

    Related Provider Taxonomies

    8 rows

    Taxonomy CodeSpecialtyNotes
    208100000XPhysical Medicine & Rehabilitation PhysicianPhysical medicine and rehabilitation, also referred to as rehabilitation medicine, is the medical specialty concerned with diagnosing, evaluating, and…
    207R00000XInternal Medicine PhysicianA physician who provides long-term, comprehensive care in the office and the hospital, managing both common and complex illness of adolescents, adults…
    207L00000XAnesthesiology PhysicianAn anesthesiologist is trained to provide pain relief and maintenance, or restoration, of a stable condition during and immediately following an opera…
    183500000XPharmacistAn individual licensed by the appropriate state regulatory agency to engage in the practice of pharmacy. The practice of pharmacy includes, but is no…
    333600000XPharmacyA facility used by pharmacists for the compounding and dispensing of medicinal preparations and other associated professional and administrative servi…
    163WD0400XDiabetes Educator Registered NurseNursing Service Providers · Registered Nurse
    261QX0203XRadiation Oncology Clinic/CenterAmbulatory Health Care Facilities · Clinic/Center
    207N00000XDermatology PhysicianA dermatologist is trained to diagnose and treat pediatric and adult patients with benign and malignant disorders of the skin, mouth, external genital…

    Related ICD-10-CM Codes

    25 rows

    ICD-10-CM CodeDescription
    G56.01Carpal tunnel syndrome, right upper limb
    G56.21Lesion of ulnar nerve, right upper limb
    G57.01Lesion of sciatic nerve, right lower limb
    M17.11Unilateral primary osteoarthritis, right knee
    M17.12Unilateral primary osteoarthritis, left knee
    M19.071Primary osteoarthritis, right ankle and foot
    M19.072Primary osteoarthritis, left ankle and foot
    M25.561Pain in right knee
    M25.562Pain in left knee
    M25.571Pain in right ankle and joints of right foot

    Showing 1–10 of 25

    Related Codes

    HCPCS-J0013-ESKETAMINE-NASAL-SPRAY-1MG

    HCPCS Level II J0013: Esketamine Nasal Spray, 1 mg

    HCPCS-J0120-INJECTION-TETRACYCLINE-250MG

    HCPCS Level II J0120: Injection, Tetracycline, up to 250 mg

    HCPCS-J0121-OMADACYCLINE-INJECTION-1MG

    HCPCS Level II J0121: Omadacycline Injection, 1 mg

    HCPCS-J0122-ERAVACYCLINE-INJECTION-1MG

    HCPCS Level II J0122: Injection, eravacycline, 1 mg

    HCPCS-J0129-ABATACEPT-INJECTION-10MG-PHYSICIAN-SUPERVISED

    HCPCS Level II J0129: Abatacept Injection, 10 mg

    HCPCS-J0130-INJECTION-ABCIXIMAB-10MG

    HCPCS Level II J0130: Injection abciximab, 10 mg

    HCPCS-J0131-INJECTION-ACETAMINOPHEN-10MG-PARENTERAL-ANALGESIC

    HCPCS Level II J0131: Injection, Acetaminophen 10 mg

    HCPCS-J0132-INJECTION-ACETYLCYSTEINE-100MG-INJECTABLE-MEDICATION

    HCPCS Level II J0132: Injection, Acetylcysteine 100 mg

    HCPCS-J0133-ACYCLOVIR-INJECTION-5MG

    HCPCS Level II J0133: Injection, Acyclovir 5 mg

    HCPCS-J0134-ACETAMINOPHEN-INJECTION-FRESENIUS-KABI-10MG

    HCPCS Level II J0134: Injection, Acetaminophen (10 mg)

    Showing 1–10 of 991

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    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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