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    OpenPayerBilling CodesProcedures / Professional ServicesHCPCS hcpcs-g9561-opioid-therapy-over-six-weeks
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    HCPCS G9561: Patients Prescribed Opiates for Longer Than Six Weeks

    HCPCS Level II code G9561 documents patients prescribed opiates for longer than six weeks and is used to indicate prolonged opioid therapy management; the service type is chronic opioid monitoring and management, typically provided in outpatient primary care, pain management clinics, or behavioral health settings.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 54-year-old patient with chronic low back pain has been prescribed opioid therapy by their primary care provider for the past nine months. The patient attends a scheduled follow-up visit in an outpatient primary care clinic to review ongoing opioid therapy, assess pain control, evaluate functional status, screen for opioid use disorder risk, and consider dose adjustment or tapering. The clinical workflow includes medication reconciliation, pain and functional assessment, review of Prescription Drug Monitoring Program (PDMP) data, urine drug testing if indicated, documentation of informed consent and treatment agreement, and coordination with pain management or behavioral health specialists as needed. Typical documentation captures duration of opioid use (>6 weeks), current medications and dosages, risk stratification, rationale for continued therapy, and any changes to the treatment plan. Typical site of service is outpatient office or ambulatory care; services may also occur in pain clinics or primary care clinics. Common payors include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, BUCA, and Medicare.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    99213Office or other outpatient visit for the evaluation and management of an established patient, typically 15 minutesCommon E/M code used for routine follow-up visits to assess ongoing opioid therapy and make medication decisions.
    99406Smoking and tobacco use cessation counseling, intermediate, 3-10 minutesOften provided as adjunct counseling during visits focused on risk reduction and behavioral interventions for patients on long-term opioids.
    80305Drug test(s), presumptive, any number of drug classes; capable of being read by immunoassay with instrumented platform, includes sample validationFrequently used for urine drug screening to monitor adherence and detect non-prescribed substances.
    96127Brief emotional/behavioral assessment (e.g., depression inventory)Used for quick screening of mood or risk factors that influence opioid management and safety planning.
    99490Chronic care management services, at least 20 minutes of clinical staff time directed by a physician or other qualified health care professional, per calendar monthMay be used when ongoing management of chronic opioid therapy is part of monthly care coordination for patients with multiple chronic conditions.

    Related Modifiers

    8 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    54Modifier ‑54 (“Surgical care only”) is appended to a CPT surgical procedure when the reporting surgeon performs the intraoperative (surgical) component but does not furnish the preoperative and/or…- Use modifier -54 when the reporting surgeon provided only the intraoperative (surgical) component of a procedure and preoperative and/or postoperative management has been or will be provided by…
    55Modifier –55 indicates the billing provider furnished only postoperative management for a procedure that has a global surgical period. According to AAPC, this modifier is appended to the same CPT…- Use modifier -55 when billing the same CPT surgical code that has a 10- or 90-day global period and you, as a provider other than the original surgeon, furnished ONLY postoperative management (no…
    56Modifier ‑56 indicates the reporting provider furnished only the preoperative management for a surgical procedure and did not perform the intraoperative or postoperative care. It is used in…- Use Modifier -56 when a provider performs only the preoperative management in a split‑care situation (one physician manages preop care while a different physician performs the intraoperative…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…

    Related Provider Taxonomies

    8 rows

    Taxonomy CodeSpecialtyNotes
    208D00000XGeneral Practice PhysicianA physician who specializes in the general practice of diagnosing, treating, and managing patients with a variety of illnesses and conditions.
    207R00000XInternal Medicine PhysicianA physician who provides long-term, comprehensive care in the office and the hospital, managing both common and complex illness of adolescents, adults…
    207L00000XAnesthesiology PhysicianAn anesthesiologist is trained to provide pain relief and maintenance, or restoration, of a stable condition during and immediately following an opera…
    208M00000XHospitalist PhysicianHospitalists are physicians whose primary professional focus is the general medical care of hospitalized patients. Their activities include patient ca…
    174V00000XClinical EthicistA clinical ethicist has been trained in bioethics and ethics case consultation. The clinical ethicist addresses medical-ethical dilemmas arising in c…
    2085N0700XNeuroradiology PhysicianA radiologist who diagnoses and treats diseases utilizing imaging procedures as they relate to the brain, spine and spinal cord, head, neck and organs…
    323P00000XPsychiatric Residential Treatment FacilityA residential treatment facility (RTF) is a facility or distinct part of a facility that provides to children and adolescents, a total, twenty-four ho…
    283XC2000XChildren's Rehabilitation HospitalHospitals · Rehabilitation Hospital

    Related ICD-10-CM Codes

    26 rows

    ICD-10-CM CodeDescription
    F11.10Opioid abuse, uncomplicated
    F11.20Opioid dependence, uncomplicated
    F11.21Opioid dependence, in remission
    G43.909Migraine, unspecified, not intractable, without status migrainosus
    G57.00Lesion of sciatic nerve, unspecified lower limb
    G89.29Other chronic pain
    G89.4Chronic pain syndrome
    M16.11Unilateral primary osteoarthritis, right hip
    M17.0Bilateral primary osteoarthritis of knee
    M17.11Unilateral primary osteoarthritis, right knee

    Showing 1–10 of 26

    Related Codes

    HCPCS-G9490-HOME-ASSESSMENT-NON-HOMEBOUND

    HCPCS G9490: Home Visit Patient Assessment for Non-Homebound Beneficiary

    HCPCS-G0008-INFLUENZA-VACCINE-ADMINISTRATION

    HCPCS G0008: Administration of Influenza Virus Vaccine

    HCPCS-G0009-PNEUMOCOCCAL-VACCINE-ADMINISTRATION

    HCPCS G0009: Administration of Pneumococcal Vaccine

    HCPCS-G0010-HEPATITIS-B-VACCINE-ADMINISTRATION

    HCPCS G0010: Administration of Hepatitis B Vaccine

    HCPCS-G0011-PREP-COUNSELING-HIV-RISK-REDUCTION-ADHERENCE

    HCPCS G0011: Individual PrEP Counseling, HIV Risk Assessment

    HCPCS-G0012-PRE-EXPOSURE-PROPHYLAXIS-INJECTION-HIV-PREVENTION

    HCPCS G0012: Injection of PrEP Drug for HIV Prevention

    HCPCS-G0013-PREP-INDIVIDUAL-COUNSELING-HIV-RISK-REDUCTION

    HCPCS G0013: Individual PrEP Counseling by Clinical Staff

    HCPCS-G0017-PSYCHOTHERAPY-CRISIS-FIRST-60-MINUTES-NON-OFFICE

    HCPCS G0017: Psychotherapy for Crisis, First 60 Minutes

    HCPCS-G0018-PSYCHOTHERAPY-CRISIS-ADDITIONAL-30-MINUTES-NON-OFFICE

    HCPCS G0018: Psychotherapy for Crisis, Additional 30 Minutes

    HCPCS-G0019-COMMUNITY-HEALTH-INTEGRATION-SDOH-CARE-COORDINATION

    HCPCS G0019: Community Health Integration, Person-Centered Assessment

    Showing 1–10 of 1996

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    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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