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    v1.0.28
    OpenPayerBilling CodesProcedures / Professional ServicesHCPCS hcpcs-g2064-comprehensive-care-management-single-high-risk-disease
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    HCPCS G2064: Comprehensive Care Management for Single High-Risk Disease

    HCPCS Level II code G2064 describes comprehensive care management services for a single high-risk disease (principal care management) involving at least 30 minutes of physician or other qualified health professional time per calendar month; the service focuses on a complex chronic condition present for at least three months that places the patient at risk of hospitalization or has recently caused hospitalization and requires a disease-specific care plan, frequent medication regimen adjustments, or unusually complex management due to comorbidities — service type: chronic care management/principal care management, typical site of service: outpatient clinic, physician office, or other ambulatory care setting.

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    Clinical & Coding Specifications

    Clinical Context

    A 72-year-old patient with a single complex chronic condition such as advanced congestive heart failure (CHF) has been enrolled in a comprehensive care management program using billing code G2064. The patient has had at least one hospitalization in the prior 12 months for decompensated heart failure and requires frequent medication adjustments (diuretics, ACE inhibitors) and a disease-specific care plan with close monitoring. Each calendar month a physician or other qualified health care professional spends at least 30 minutes on care coordination activities focused on the CHF: medication reconciliation and adjustment, coordination with cardiology and home health, arranging durable medical equipment, patient education on weight and symptom monitoring, and updates to the disease-specific care plan.

    Clinical workflow: After hospital discharge or identification as high-risk, the primary clinician documents the eligible chronic condition and develops a disease-specific care plan. Monthly care management encounters are scheduled (telephonic or face-to-face) and documented, with time tracked to confirm at least 30 minutes of clinician time. Interventions documented include medication regimen changes, referrals to specialists, care-plan revisions, and documentation of risk for hospitalization. Communication with other care team members (nurse care manager, pharmacist, home health) and patient/caregiver education are recorded. Billing uses G2064 for the monthly comprehensive care management service when all code criteria are met.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    99490Chronic care management services, at least 20 minutes of clinical staff time directed by a physician or other qualified health care professional, per calendar month, with required elementsMay be billed for less complex, time-based chronic care management when the patient has multiple chronic conditions but not a single high-risk disease requiring G2064.
    99487Complex chronic care management services, first hour of clinical staff time directed by a physician or other qualified health care professional, per calendar month, with required elements and high-complexity medical decision makingUsed for patients with multiple complex chronic conditions requiring higher complexity care management; often coordinated with G2064 when single-condition focus differs.
    99439Chronic care management services, each additional 20 minutes of clinical staff time directed by a physician or other qualified health care professional, per calendar monthUsed to add time-based increments for chronic care management when additional documented time is needed beyond base services.
    99495Transitional care management services with moderate medical decision complexity (communication within 2 business days, face-to-face within 14 calendar days)Often performed after hospital discharge before enrolling or concurrently with monthly comprehensive disease-focused management under G2064.
    99091Collection and interpretation of physiologic data digitally stored and/or transmitted by the patient to the physician or other qualified health care professional, requiring a minimum of 30 minutes of timeMay be used when RPM data collection and interpretation contribute to the monthly care management for the single high-risk disease.

    Related Modifiers

    9 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    54Modifier ‑54 (“Surgical care only”) is appended to a CPT surgical procedure when the reporting surgeon performs the intraoperative (surgical) component but does not furnish the preoperative and/or…- Use modifier -54 when the reporting surgeon provided only the intraoperative (surgical) component of a procedure and preoperative and/or postoperative management has been or will be provided by…
    55Modifier –55 indicates the billing provider furnished only postoperative management for a procedure that has a global surgical period. According to AAPC, this modifier is appended to the same CPT…- Use modifier -55 when billing the same CPT surgical code that has a 10- or 90-day global period and you, as a provider other than the original surgeon, furnished ONLY postoperative management (no…
    56Modifier ‑56 indicates the reporting provider furnished only the preoperative management for a surgical procedure and did not perform the intraoperative or postoperative care. It is used in…- Use Modifier -56 when a provider performs only the preoperative management in a split‑care situation (one physician manages preop care while a different physician performs the intraoperative…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…

    Related Provider Taxonomies

    8 rows

    Taxonomy CodeSpecialtyNotes
    207Q00000XFamily Medicine PhysicianFamily Medicine is the medical specialty which is concerned with the total health care of the individual and the family. It is the specialty in breadt…
    207R00000XInternal Medicine PhysicianA physician who provides long-term, comprehensive care in the office and the hospital, managing both common and complex illness of adolescents, adults…
    208000000XPediatrics PhysicianA pediatrician is concerned with the physical, emotional and social health of children from birth to young adulthood. Care encompasses a broad spectru…
    363L00000XNurse Practitioner(1) A registered nurse provider with a graduate degree in nursing prepared for advanced practice involving independent and interdependent decision mak…
    367500000XCertified Registered Nurse Anesthetist(1) A licensed registered nurse with advanced specialty education in anesthesia who, in collaboration with appropriate health care professionals, prov…
    2080P0205XPediatric Endocrinology PhysicianA pediatrician who provides expert care to infants, children and adolescents who have diseases that result from an abnormality in the endocrine glands…
    207YX0905XOtolaryngology/Facial Plastic Surgery PhysicianAn otolaryngologist who specializes in the diagnosis and surgical treatment of head and neck conditions.
    208200000XPlastic Surgery PhysicianA plastic surgeon deals with the repair, reconstruction or replacement of physical defects of form or function involving the skin, musculoskeletal sys…

    Related Codes

    HCPCS-G9490-HOME-ASSESSMENT-NON-HOMEBOUND

    HCPCS G9490: Home Visit Patient Assessment for Non-Homebound Beneficiary

    HCPCS-G0008-INFLUENZA-VACCINE-ADMINISTRATION

    HCPCS G0008: Administration of Influenza Virus Vaccine

    HCPCS-G0009-PNEUMOCOCCAL-VACCINE-ADMINISTRATION

    HCPCS G0009: Administration of Pneumococcal Vaccine

    HCPCS-G0010-HEPATITIS-B-VACCINE-ADMINISTRATION

    HCPCS G0010: Administration of Hepatitis B Vaccine

    HCPCS-G0011-PREP-COUNSELING-HIV-RISK-REDUCTION-ADHERENCE

    HCPCS G0011: Individual PrEP Counseling, HIV Risk Assessment

    HCPCS-G0012-PRE-EXPOSURE-PROPHYLAXIS-INJECTION-HIV-PREVENTION

    HCPCS G0012: Injection of PrEP Drug for HIV Prevention

    HCPCS-G0013-PREP-INDIVIDUAL-COUNSELING-HIV-RISK-REDUCTION

    HCPCS G0013: Individual PrEP Counseling by Clinical Staff

    HCPCS-G0017-PSYCHOTHERAPY-CRISIS-FIRST-60-MINUTES-NON-OFFICE

    HCPCS G0017: Psychotherapy for Crisis, First 60 Minutes

    HCPCS-G0018-PSYCHOTHERAPY-CRISIS-ADDITIONAL-30-MINUTES-NON-OFFICE

    HCPCS G0018: Psychotherapy for Crisis, Additional 30 Minutes

    HCPCS-G0019-COMMUNITY-HEALTH-INTEGRATION-SDOH-CARE-COORDINATION

    HCPCS G0019: Community Health Integration, Person-Centered Assessment

    Showing 1–10 of 1996

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    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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