HCPCS Level II E1353: Regulator for Oxygen/Respiratory Equipment

HCPCS Level II code E1353 describes a regulator device used with oxygen or other medical gas delivery systems; the service type is durable medical equipment and the typical site of service is home or outpatient settings where patients receive supplemental oxygen or respiratory support.

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HCPCS Level II E1353: Regulator for Oxygen/Respiratory Equipment

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Get alerted when payer policies referencing E1353 are released or updated.

Monitor payer policy activity

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Clinical & Coding Specifications

Clinical Context

A 62-year-old patient with chronic obstructive pulmonary disease (COPD) and progressive hypoventilation is evaluated in an outpatient durable medical equipment clinic for long-term oxygen therapy and ventilatory support. A clinician identifies the need for an oxygen regulator to control flow from a stationary oxygen concentrator or compressed oxygen cylinder during home therapy. The patient presents with current prescriptions for supplemental oxygen and demonstrates inability to safely self-regulate flow settings due to dexterity limitations. The respiratory therapist assesses device compatibility, determines the regulator model required for the patient’s oxygen source, documents medical necessity, and arranges delivery and patient education.

Typical clinical workflow:

Referral from pulmonologist or primary care provider with order for home oxygen support and associated supplies.
Respiratory therapist evaluates patient’s oxygen delivery system, measures required flow range, and selects an appropriate regulator (billing code E1353).
Supplier obtains prior authorization if required, documents clinical indications (e.g., hypoxemia, COPD exacerbation history), and records supplier and clinician taxonomy and supplier invoice details.
Delivery to patient’s home with education on use, safety checks, and documentation of serial numbers and linkage to the oxygen source.

Related CPT Codes

CPT Code	Description	Relationship to This Procedure
`94660`	Continuous positive airway pressure ventilation (CPAP), initiation and management	May be performed in evaluation of hypoventilation where a regulator for supplemental oxygen is provided concurrently for home therapy.
`94010`	Spirometry, including graphic record, total and timed vital capacity	Pulmonary function testing that commonly precedes prescription of home oxygen and related regulator equipment.
`94760`	Noninvasive ear or pulse oximetry for oxygen saturation; single determination	Used during assessment to document oxygenation and establish flow settings that dictate regulator specifications.
`99070`	Supplies and materials (not otherwise specified) provided by the physician over and above those usually included with the office visit	May be used by suppliers or clinicians to bill for small additional supplies or attachments associated with the regulator.
`99214`	Office or other outpatient visit for the evaluation and management of an established patient	Typical evaluation visit code when assessing need for home oxygen and ordering a regulator.

Related Modifiers

5 rows

Modifier	Description	When to Use
52	Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…	- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
53	Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…	- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
62	Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…	- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
78	CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…	- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
80	CPT® Modifier 80 (Assistant Surgeon) is appended to a surgical CPT code when a physician (MD or DO) provides full, continuous assistance throughout the operative procedure. It is intended only for…	- Use CPT Modifier -80 when a physician (MD or DO) serves as an assistant surgeon and provides full, continuous assistance throughout the entire operative procedure; append -80 to the surgical CPT…

Related Provider Taxonomies

8 rows

Taxonomy Code	Specialty	Notes
1835P1300X	Psychiatric Pharmacist	A licensed pharmacist who has demonstrated specialized knowledge and skill in optimizing care of patients with psychiatric illness by assessing and mo…
374700000X	Technician	(1) A person with specialized training in a narrow field of expertise whose occupation requires training and is skilled in specific technical processe…
261QB0400X	Birthing Clinic/Center	A freestanding birth center is a health facility other than a hospital where childbirth is planned to occur away from the pregnant woman's residence, …
2080H0002X	Pediatric Hospice and Palliative Medicine Physician	A pediatrician with special knowledge and skills to prevent and relieve the suffering experienced by patients with life-limiting illnesses. This speci…
2084H0002X	Hospice and Palliative Medicine (Psychiatry & Neurology) Physician	A psychiatrist or neurologist with special knowledge and skills to prevent and relieve the suffering experienced by patients with life-limiting illnes…
2279P1006X	Pulmonary Function Technologist Registered Respiratory Therapist	An individual who is trained and qualified to perform pulmonary diagnostic tests. In the course of conducting these tests, the Pulmonary Function Tec…
2082S0105X	Surgery of the Hand (Plastic Surgery) Physician	A plastic surgeon with additional training in the investigation, preservation, and restoration by medical, surgical and rehabilitative means of all st…
2279P3900X	Neonatal/Pediatric Registered Respiratory Therapist	The care and treatment of premature infants, newborns and children. This includes management of mechanical ventilation, assessment, diagnostics and g…

Related ICD-10-CM Codes

25 rows

ICD-10-CM Code	Description
E03.9	Hypothyroidism, unspecified
E10.9	Type 1 diabetes mellitus without complications
E11.9	Type 2 diabetes mellitus without complications
E66.9	Obesity, unspecified
E78.5	Hyperlipidemia, unspecified
F32.9	Major depressive disorder, single episode, unspecified
F41.9	Anxiety disorder, unspecified
G30.9	Alzheimer's disease, unspecified
G47.00	Insomnia, unspecified
I10	Essential (primary) hypertension

Showing 1–10 of 25

HCPCS E0100: Cane, Adjustable or Fixed, With Tip

HCPCS-E0105-CANE-QUAD-THREE-PRONG-MOBILITY-AID

HCPCS Level II E0105: Cane, Quad or Three-Prong, Includes Tips

HCPCS-E0110-FOREARM-CRUTCHES-PAIR-DME-MOBILITY

HCPCS Level II E0110: Forearm Crutches, Pair, Complete with Tips and Handgrips

HCPCS-E0111-CRUTCH-FOREARM-DURABLE-MEDICAL-EQUIPMENT

HCPCS Level II E0111: Crutch, Forearm, With Tip and Handgrips

HCPCS-E0112-UNDERARM-WOOD-CRUTCHES-PAIR

HCPCS Level II E0112: Underarm Wooden Crutches, Pair

HCPCS-E0113-CRUTCH-UNDERARM-WOOD-ADJUSTABLE-FIXED-WITH-PAD-TIP-HANDGRIP

HCPCS Level II E0113: Crutch Underarm, Wood, Adjustable or Fixed

HCPCS-E0114-UNDERARM-CRUTCHES-PAIR-ADJUSTABLE-FIXED

HCPCS Level II E0114: Underarm (Axillary) Crutches, Adjustable or Fixed, Pair

HCPCS-E0116-UNDERARM-CRUTCH-NON-WOOD-ADJUSTABLE-FIXED

HCPCS E0116: Underarm Crutch, Non-Wood, Adjustable/Fixed with Pad

HCPCS-E0117-ARTICULATING-SPRING-ASSISTED-UNDERARM-CRUTCH

HCPCS Level II E0117: Crutch, Underarm, Articulating, Spring-Assisted

HCPCS-E0118-LOWER-LEG-PLATFORM-CRUTCH-SUBSTITUTE

HCPCS E0118: Crutch Substitute, Lower Leg Platform

Showing 1–10 of 670

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

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Trek Health ingests and normalizes Transparency in Coverage data and payer policy updates to give provider organizations a clear view of how commercial reimbursement behaves across markets, payers, and services. Our platform transforms raw payer disclosures into structured intelligence that supports contract evaluation, payer negotiations, and service line strategy. By combining market benchmarks with ongoing policy visibility, Trek helps teams identify variability, risk, and opportunity in commercial reimbursement. The result is faster insight, stronger negotiating positions, and more informed financial decisions.

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Clinical & Coding Specifications

Clinical Context

Typical clinical workflow:

Referral from pulmonologist or primary care provider with order for home oxygen support and associated supplies.
Respiratory therapist evaluates patient’s oxygen delivery system, measures required flow range, and selects an appropriate regulator (billing code E1353).
Supplier obtains prior authorization if required, documents clinical indications (e.g., hypoxemia, COPD exacerbation history), and records supplier and clinician taxonomy and supplier invoice details.
Delivery to patient’s home with education on use, safety checks, and documentation of serial numbers and linkage to the oxygen source.

Related CPT Codes

CPT Code	Description	Relationship to This Procedure
`94660`	Continuous positive airway pressure ventilation (CPAP), initiation and management	May be performed in evaluation of hypoventilation where a regulator for supplemental oxygen is provided concurrently for home therapy.
`94010`	Spirometry, including graphic record, total and timed vital capacity	Pulmonary function testing that commonly precedes prescription of home oxygen and related regulator equipment.
`94760`	Noninvasive ear or pulse oximetry for oxygen saturation; single determination	Used during assessment to document oxygenation and establish flow settings that dictate regulator specifications.
`99070`	Supplies and materials (not otherwise specified) provided by the physician over and above those usually included with the office visit	May be used by suppliers or clinicians to bill for small additional supplies or attachments associated with the regulator.
`99214`	Office or other outpatient visit for the evaluation and management of an established patient	Typical evaluation visit code when assessing need for home oxygen and ordering a regulator.

Related Modifiers

5 rows

Modifier	Description	When to Use
52	Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…	- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
53	Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…	- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
62	Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…	- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
78	CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…	- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
80	CPT® Modifier 80 (Assistant Surgeon) is appended to a surgical CPT code when a physician (MD or DO) provides full, continuous assistance throughout the operative procedure. It is intended only for…	- Use CPT Modifier -80 when a physician (MD or DO) serves as an assistant surgeon and provides full, continuous assistance throughout the entire operative procedure; append -80 to the surgical CPT…

Related Provider Taxonomies

8 rows

Taxonomy Code	Specialty	Notes
1835P1300X	Psychiatric Pharmacist	A licensed pharmacist who has demonstrated specialized knowledge and skill in optimizing care of patients with psychiatric illness by assessing and mo…
374700000X	Technician	(1) A person with specialized training in a narrow field of expertise whose occupation requires training and is skilled in specific technical processe…
261QB0400X	Birthing Clinic/Center	A freestanding birth center is a health facility other than a hospital where childbirth is planned to occur away from the pregnant woman's residence, …
2080H0002X	Pediatric Hospice and Palliative Medicine Physician	A pediatrician with special knowledge and skills to prevent and relieve the suffering experienced by patients with life-limiting illnesses. This speci…
2084H0002X	Hospice and Palliative Medicine (Psychiatry & Neurology) Physician	A psychiatrist or neurologist with special knowledge and skills to prevent and relieve the suffering experienced by patients with life-limiting illnes…
2279P1006X	Pulmonary Function Technologist Registered Respiratory Therapist	An individual who is trained and qualified to perform pulmonary diagnostic tests. In the course of conducting these tests, the Pulmonary Function Tec…
2082S0105X	Surgery of the Hand (Plastic Surgery) Physician	A plastic surgeon with additional training in the investigation, preservation, and restoration by medical, surgical and rehabilitative means of all st…
2279P3900X	Neonatal/Pediatric Registered Respiratory Therapist	The care and treatment of premature infants, newborns and children. This includes management of mechanical ventilation, assessment, diagnostics and g…

Related ICD-10-CM Codes

25 rows

ICD-10-CM Code	Description
E03.9	Hypothyroidism, unspecified
E10.9	Type 1 diabetes mellitus without complications
E11.9	Type 2 diabetes mellitus without complications
E66.9	Obesity, unspecified
E78.5	Hyperlipidemia, unspecified
F32.9	Major depressive disorder, single episode, unspecified
F41.9	Anxiety disorder, unspecified
G30.9	Alzheimer's disease, unspecified
G47.00	Insomnia, unspecified
I10	Essential (primary) hypertension

Showing 1–10 of 25

HCPCS E0100: Cane, Adjustable or Fixed, With Tip

HCPCS-E0105-CANE-QUAD-THREE-PRONG-MOBILITY-AID

HCPCS Level II E0105: Cane, Quad or Three-Prong, Includes Tips

HCPCS-E0110-FOREARM-CRUTCHES-PAIR-DME-MOBILITY

HCPCS Level II E0110: Forearm Crutches, Pair, Complete with Tips and Handgrips

HCPCS-E0111-CRUTCH-FOREARM-DURABLE-MEDICAL-EQUIPMENT

HCPCS Level II E0111: Crutch, Forearm, With Tip and Handgrips

HCPCS-E0112-UNDERARM-WOOD-CRUTCHES-PAIR

HCPCS Level II E0112: Underarm Wooden Crutches, Pair

HCPCS-E0113-CRUTCH-UNDERARM-WOOD-ADJUSTABLE-FIXED-WITH-PAD-TIP-HANDGRIP

HCPCS Level II E0113: Crutch Underarm, Wood, Adjustable or Fixed

HCPCS-E0114-UNDERARM-CRUTCHES-PAIR-ADJUSTABLE-FIXED

HCPCS Level II E0114: Underarm (Axillary) Crutches, Adjustable or Fixed, Pair

HCPCS-E0116-UNDERARM-CRUTCH-NON-WOOD-ADJUSTABLE-FIXED

HCPCS E0116: Underarm Crutch, Non-Wood, Adjustable/Fixed with Pad

HCPCS-E0117-ARTICULATING-SPRING-ASSISTED-UNDERARM-CRUTCH

HCPCS Level II E0117: Crutch, Underarm, Articulating, Spring-Assisted

HCPCS-E0118-LOWER-LEG-PLATFORM-CRUTCH-SUBSTITUTE

HCPCS E0118: Crutch Substitute, Lower Leg Platform

Showing 1–10 of 670

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

OpenPayer

HCPCS Level II E1353: Regulator for Oxygen/Respiratory Equipment

Sign up for hcpcs E1353 policy alerts

OpenPayer

HCPCS Level II E1353: Regulator for Oxygen/Respiratory Equipment

Sign up for hcpcs E1353 policy alerts

Clinical & Coding Specifications

Clinical Context

Related CPT Codes

Related Modifiers

Related Provider Taxonomies

Related ICD-10-CM Codes

Related Codes

References

Clinical & Coding Specifications

Clinical Context

Related CPT Codes

Related Modifiers

Related Provider Taxonomies

Related ICD-10-CM Codes

Related Codes

References

HCPCS Level II E1353: Regulator for Oxygen/Respiratory Equipment

Sign up for hcpcs E1353 policy alerts

HCPCS Level II E1353: Regulator for Oxygen/Respiratory Equipment

Sign up for hcpcs E1353 policy alerts

Clinical & Coding Specifications

Clinical Context

Related CPT Codes

Related Modifiers

Related Provider Taxonomies

Related ICD-10-CM Codes

Related Codes

What does HCPCS code E1353 represent and where is it typically used?

In what clinical situations is E1353 commonly used?

Which modifiers are commonly used with E1353 and when do they apply?

What related CPT codes should be considered when billing for a regulator under E1353?

Which payers and provider taxonomies are referenced for E1353 claims submissions?

References

Clinical & Coding Specifications

Clinical Context

Related CPT Codes

Related Modifiers

Related Provider Taxonomies

Related ICD-10-CM Codes

Related Codes

What does HCPCS code E1353 represent and where is it typically used?

In what clinical situations is E1353 commonly used?

Which modifiers are commonly used with E1353 and when do they apply?

What related CPT codes should be considered when billing for a regulator under E1353?

Which payers and provider taxonomies are referenced for E1353 claims submissions?

References