HCPCS Level II code C9355 denotes a collagen nerve cuff (neuromatrix), billed per 0.5 centimeter length. The code applies to an implantable biologic device used in surgical peripheral nerve repair to provide scaffold support and potentially improve regeneration outcomes. As an HCPCS Level II supply code, C9355 matters nationally for hospital and ambulatory surgery billing, device supply inventory, and surgical implant coding clarity.

Key payers covered in this analysis include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find a concise overview of how the code is used in surgical settings, expected sites of service, and the clinical context for peripheral nerve reconstruction procedures. The publication presents benchmark considerations for utilization and claim processing, common modifier usage patterns when applicable, and gaps where payer-specific coverage guidance or pricing information is not available.

This resource is intended to help coding, billing, and procurement teams understand the clinical purpose of C9355, the typical service environment, and what to look for when preparing claims and documentation for collagen nerve cuff implants.