HCPCS Level II code C9250 denotes a 2 ml vial of human plasma fibrin sealant (Artiss), vapor-heated and solvent-detergent processed, used as a surgical hemostatic and tissue sealant. This biologic adjunct is applied during operative and procedural care to control bleeding and facilitate tissue adherence, making it relevant across surgical specialties including plastic, reconstructive, and general surgery.

Key national payers covered in this analysis include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. The publication outlines how C9250 is classified for billing, summarizes payer coverage patterns, and highlights the clinical contexts in which the product is typically used.

Readers will find benchmarks for utilization and reimbursement structures, summaries of relevant payer policy themes, and clinical context for appropriate service lines and sites of service. The report also identifies common modifiers associated with procedural supply billing and notes gaps where data were not provided. This summary is intended for a national audience of billing professionals, revenue cycle managers, and surgical clinical leadership seeking concise guidance on the classification and billing context of HCPCS Level II code C9250.