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    v1.0.28
    OpenPayerBilling CodesOutpatient PPSHCPCS hcpcs-c7516-coronary-angiography-with-ivus-oct
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    HCPCS C7516: Coronary Angiography with IVUS/OCT Imaging

    HCPCS Level II code C7516 describes catheter placement in coronary artery(s) for coronary angiography with intraprocedural injection(s) and endoluminal imaging of the initial coronary vessel or graft using intravascular ultrasound (IVUS) or optical coherence tomography (OCT), including imaging supervision, interpretation, and report; service type: diagnostic coronary angiography with intravascular imaging during evaluation and/or therapeutic intervention; typical site of service: cardiac catheterization laboratory or interventional cardiology suite.

    For related coverage guidance, see recent payer policy updates: Cardiac Computed Tomography (CCT)/Coronary Computed Tomographic Angiography (CCTA), Cardiovascular Disease Risk Assessment, Biomarkers for Myocardial Infarction and Chronic Heart Failure.

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    Clinical & Coding Specifications

    Clinical Context

    A 64-year-old male with known coronary artery disease and recurrent exertional angina is referred for invasive coronary angiography to evaluate graft patency and native coronary lesions. The patient presents to the cardiac catheterization laboratory after pre-procedural consent and usual pre-op assessment (including review of antiplatelet/anticoagulant medications and renal function). Vascular access is achieved (femoral or radial) and selective catheterization of the coronary arteries is performed with intraprocedural contrast injections to define luminal stenoses. During the diagnostic evaluation, the interventional cardiologist performs intraluminal imaging of an initial coronary vessel using intravascular ultrasound (IVUS) to better characterize lesion morphology, measure reference vessel diameter, and guide decision-making for percutaneous coronary intervention (PCI). Imaging supervision, interpretation, and a written report are completed and documented in the procedural note. The typical site of service is an ambulatory catheterization laboratory or hospital cardiac catheterization suite. The service type is invasive diagnostic coronary angiography with intravascular imaging (IVUS/OCT) performed during diagnostic evaluation or therapeutic intervention.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    93454Catheter placement in coronary artery(s) for coronary angiography, including intraprocedural injections for coronary angiography, with or without left heart catheterization when performed; coronary angiography onlyOften reported for diagnostic coronary angiography; aligns with catheter placement and contrast injections portion of the service.
    93458Combined diagnostic and therapeutic coronary angiography including intraprocedural injection(s) for coronary angiography, and when performed, left heart catheterization; with coronary angiography and percutaneous transluminal coronary angioplasty (PTCA) when performedReported when diagnostic angiography is followed by therapeutic PCI during the same session; complements intravascular imaging that guides intervention.
    92928Percutaneous transcatheter placement of intracoronary stent(s), with coronary angioplasty when performed; single major coronary artery or branchBilled when stent placement is performed after lesion assessment with IVUS/OCT; intravascular imaging can guide stent sizing and optimization.
    92920Percutaneous transluminal coronary angioplasty (PTCA); single major coronary artery or branchUsed when balloon angioplasty is performed as the therapeutic component following angiography and imaging.
    93318Echocardiography, transesophageal, real-time with image documentation (2D) with or without M-mode recording; intraoperative or other procedure, including imaging supervision, interpretation and reportUsed when intra-procedural transesophageal echocardiography is performed concurrently for hemodynamic assessment or support during complex interventions.
    93567Intravascular ultrasound (IVUS), including image acquisition and interpretation; for intraluminal imaging during coronary procedures (when reported separately per payer policy)Used when IVUS imaging is reported separately from angiography interventions per payer guidance; complements C7516 when payers allow separate reporting.

    Related Modifiers

    8 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    73Modifier 73 indicates a facility-level outpatient hospital or ASC procedure that was discontinued after the patient was prepared and taken to the procedure/operating room but before any anesthesia…- When to use: Apply CPT modifier 73 on the FACILITY (outpatient hospital or ASC) claim when the patient has been fully prepared and physically taken into the procedure/operating room but the…

    Related Provider Taxonomies

    8 rows

    Taxonomy CodeSpecialtyNotes
    207RC0000XCardiovascular Disease PhysicianAn internist who specializes in diseases of the heart and blood vessels and manages complex cardiac conditions such as heart attacks and life-threaten…
    207RG0300XGeriatric Medicine (Internal Medicine) PhysicianAn internist who has special knowledge of the aging process and special skills in the diagnostic, therapeutic, preventive and rehabilitative aspects o…
    208000000XPediatrics PhysicianA pediatrician is concerned with the physical, emotional and social health of children from birth to young adulthood. Care encompasses a broad spectru…
    225700000XMassage TherapistAn individual trained in the manipulation of tissues (as by rubbing, stroking, kneading, or tapping) with the hand or an instrument for remedial or hy…
    224P00000XProsthetistA health care professional who is specifically educated and trained to manage comprehensive prosthetic patient care for individuals who have sustained…
    103TR0400XRehabilitation PsychologistA psychologist who specializes in the study and application of psychological principles on behalf of persons who have disability due to injury or illn…
    1223X2210XOrofacial Pain DentistryA dentist who assesses, diagnoses, and treats patients with complex chronic orofacial pain and dysfunction disorders, oromotor and jaw behavior disord…
    207RT0003XTransplant Hepatology PhysicianAn internist with special knowledge and the skill required of a gastroenterologist to care for patients prior to and following hepatic transplantation…

    Related Payer Policy Updates

    Specialty: Cardiology1 / 3

    6 rows

    PolicyPayerEffective Date
    Cardiac Computed Tomography (CCT)/Coronary Computed Tomographic Angiography (CCTA)univerahealthcare2026-10-15
    Cardiovascular Disease Risk AssessmentOscar Health2026-10-01
    Biomarkers for Myocardial Infarction and Chronic Heart FailureOscar Health2026-10-01
    Multiple Procedure Payment Reduction for Diagnostic Cardiovascular ProceduresBlue Cross Blue Shield - Maine2026-10-01
    Cardiovascular Disease Risk Assessmentblue cross blue shield - louisiana2026-09-15
    Cardiovascular Disease Risk AssessmentBlue Cross Blue Shield - New Mexico2026-09-04

    Related Codes

    HCPCS-C1713-IMPLANTABLE-ANCHOR-SCREW-BONE-FIXATION

    HCPCS C1713: Anchor/Screw for Bone or Soft Tissue Fixation (Implantable)

    HCPCS-C1714-TRANSLUMINAL-DIRECTIONAL-ATHERECTOMY-CATHETER

    HCPCS C1714: Catheter, transluminal atherectomy, directional

    HCPCS-C1715-BRACHYTHERAPY-NEEDLE

    HCPCS C1715: Brachytherapy Needle

    HCPCS-C1716-BRACHYTHERAPY-GOLD-198-SOURCE

    HCPCS C1716: Brachytherapy Source, Gold-198, Per Source

    HCPCS-C1717-HDR-BRACHYTHERAPY-IRIDIUM-192-SOURCE

    HCPCS C1717: HDR Iridium-192 Brachytherapy Source, Per Source

    HCPCS-C1719-BRACHYTHERAPY-IRIDIUM-192-SOURCE-NON-STRANDED

    HCPCS C1719: Brachytherapy Source, Iridium-192, Non-Stranded

    HCPCS-C1721-IMPLANTABLE-DUAL-CHAMBER-CARDIOVERTER-DEFIBRILLATOR

    HCPCS C1721: Cardioverter-Defibrillator, Dual Chamber (Implantable)

    HCPCS-C1724-ROTATIONAL-TRANSLUMINAL-ATHERECTOMY-CATHETER

    HCPCS Level II C1724: Rotational Transluminal Atherectomy Catheter

    HCPCS-C1725-TRANSLUMINAL-ANGIOPLASTY-CATHETER-NON-LASER

    HCPCS Level II C1725: Transluminal Angioplasty Catheter, Non-Laser

    HCPCS-C1726-NON-VASCULAR-BALLOON-DILATATION-CATHETER

    HCPCS C1726: Catheter, Balloon Dilatation, Non-Vascular

    Showing 1–10 of 603

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    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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