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    v1.0.28
    OpenPayerBilling CodesAdministrative, Miscellaneous and InvestigationalHCPCS hcpcs-a9563-sodium-phosphate-p32-therapeutic-per-millicurie
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    HCPCS Level II A9563: Sodium Phosphate P-32 Therapeutic, per mCi

    HCPCS Level II code A9563 describes sodium phosphate p-32, therapeutic, per millicurie, a radiopharmaceutical dosed by activity for therapeutic nuclear medicine applications; the service involves preparation and administration of the radiotherapeutic agent and is typically delivered in outpatient nuclear medicine or radiation oncology settings where sterile radiopharmaceutical handling and radiation safety measures are performed.

    For related coverage guidance, see recent payer policy updates: Interferential Stimulation Devices (for home use), Durable Medical Equipment (DME): Tumor Treating Fields (Alternating Electric Field Therapy) Medical Guideline, Durable Medical Equipment (DME): Bone Growth Stimulators Medical Guideline.

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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is an adult with a history of hyperthyroidism or a thyroid nodule refractory to medical therapy, referred to nuclear medicine for targeted radioisotope therapy. The treating team is commonly an endocrinologist or oncologist who documents indication, prior therapies, and informed consent. On the day of service the patient is evaluated in an outpatient nuclear medicine or hospital outpatient infusion suite. Baseline vitals and pregnancy status (where applicable) are confirmed. The nuclear medicine physician orders A9563 (sodium phosphate P-32, therapeutic, per millicurie) with the prescribed activity in millicuries. A radiopharmacy prepares the unit dose, verifies radioactivity, and performs appropriate labeling and radiation safety checks. The patient receives the dose orally or via the indicated route per protocol; staff monitor for immediate adverse reactions and provide post-therapy radiation safety and discharge instructions. Documentation includes indication, dose administered (millicurie), lot number, route, time of administration, consent, and any concurrent medications. Billing captures the per-millicurie charge using A9563 with appropriate modifiers to reflect unusual circumstances, multiple providers, or technical components as applicable.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    77336Continuing medical physics consultation, review of treatment chart, review of patient and treatment, and dosimetry as needed for radiopharmaceutical therapyUsed when dosimetry review or treatment planning is required for therapeutic radiopharmaceuticals
    96401Chemotherapy administration, subcutaneous or intramuscular; non-hormonal anti-neoplasticMay be used for administration reporting if parenteral therapeutic radiopharmaceuticals are administered in an infusion setting (site-dependent applicability)
    99070Supplies and materials (except spectacles), used for medical purposes, over and above those usually included with the office visit or other services rendered (eg, syringes, gauze)Used to report additional supplies related to radiopharmaceutical preparation and administration
    96415Chemotherapy administration, intravenous, push technique up to 15 minutesApplicable if short intravenous administration technique is used for certain radiopharmaceuticals (use per payer policy)
    99001Laboratory procedures and non-physician services in hospital that are not otherwise classifiedUse for ancillary services related to handling and disposal of radioactive waste when facility-specific billing is required

    Related Modifiers

    9 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    54Modifier ‑54 (“Surgical care only”) is appended to a CPT surgical procedure when the reporting surgeon performs the intraoperative (surgical) component but does not furnish the preoperative and/or…- Use modifier -54 when the reporting surgeon provided only the intraoperative (surgical) component of a procedure and preoperative and/or postoperative management has been or will be provided by…
    55Modifier –55 indicates the billing provider furnished only postoperative management for a procedure that has a global surgical period. According to AAPC, this modifier is appended to the same CPT…- Use modifier -55 when billing the same CPT surgical code that has a 10- or 90-day global period and you, as a provider other than the original surgeon, furnished ONLY postoperative management (no…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    80CPT® Modifier 80 (Assistant Surgeon) is appended to a surgical CPT code when a physician (MD or DO) provides full, continuous assistance throughout the operative procedure. It is intended only for…- Use CPT Modifier -80 when a physician (MD or DO) serves as an assistant surgeon and provides full, continuous assistance throughout the entire operative procedure; append -80 to the surgical CPT…
    82Modifier 82 is appended to a surgical CPT code to indicate that an attending physician acted as an assistant because a qualified resident surgeon was unavailable. In teaching hospitals it documents…- When to use: Append modifier 82 in teaching-hospital settings to indicate a physician served as an assistant surgeon because a qualified resident surgeon was unavailable (includes situations where…

    Related Provider Taxonomies

    8 rows

    Taxonomy CodeSpecialtyNotes
    207L00000XAnesthesiology PhysicianAn anesthesiologist is trained to provide pain relief and maintenance, or restoration, of a stable condition during and immediately following an opera…
    363A00000XPhysician AssistantA physician assistant is a person who has successfully completed an accredited education program for physician assistant, is licensed by the state and…
    208000000XPediatrics PhysicianA pediatrician is concerned with the physical, emotional and social health of children from birth to young adulthood. Care encompasses a broad spectru…
    208D00000XGeneral Practice PhysicianA physician who specializes in the general practice of diagnosing, treating, and managing patients with a variety of illnesses and conditions.
    320600000XIntellectual and/or Developmental Disabilities Residential Treatment FacilityA residential facility that provides habilitation services and other care and treatment to adults or children diagnosed with developmental and intelle…
    2472E0500XEEG TechnicianTechnologists, Technicians & Other Technical Service Providers · Technician, Other
    163WM1400XNurse Massage Therapist (NMT)Nursing Service Providers · Registered Nurse
    376K00000XNurse's Aide(1) An unlicensed individual who is trained to function in an assistive role to the licensed nurse in the provision of patient/client activities as de…

    Related ICD-10-CM Codes

    26 rows

    ICD-10-CM CodeDescription
    C22.0Liver cell carcinoma
    C41.9Malignant neoplasm of bone and articular cartilage, unspecified
    C43.9Malignant melanoma of skin, unspecified
    C73Malignant neoplasm of thyroid gland
    C75.1Malignant neoplasm of pituitary gland
    C75.2Malignant neoplasm of craniopharyngeal duct
    C75.8Malignant neoplasm with pluriglandular involvement, unspecified
    D09.3Carcinoma in situ of thyroid and other endocrine glands
    D34Benign neoplasm of thyroid gland
    D44.3Neoplasm of uncertain behavior of pituitary gland

    Showing 1–10 of 26

    Related Payer Policy Updates

    Specialty: Durable Medical Equipment (DME)1 / 3

    5 rows

    PolicyPayerEffective Date
    Interferential Stimulation Devices (for home use)Moda Health2026-10-01
    Durable Medical Equipment (DME): Tumor Treating Fields (Alternating Electric Field Therapy) Medical GuidelineWPS Health Insurance2026-10-01
    Durable Medical Equipment (DME): Bone Growth Stimulators Medical GuidelineWPS Health Insurance2026-10-01
    General Durable Medical Equipment (DME) Medical GuidelineWPS Health Insurance2026-10-01
    Prior Authorization for Durable Medical Equipment (DME)Blue Cross Blue Shield - Rhode Island2026-10-01

    Related Codes

    HCPCS-A9150-NON-PRESCRIPTION-DRUGS

    HCPCS Level II A9150: Non-prescription Drugs

    HCPCS-A9152-SINGLE-ORAL-VITAMIN-MINERAL-DOSE

    HCPCS A9152: Single Oral Vitamin/Mineral/Trace Element

    HCPCS-A9153-MULTIVITAMIN-ORAL-PER-DOSE

    HCPCS A9153: Multiple Vitamins, Oral, Per Dose

    HCPCS-A9154-ARTIFICIAL-SALIVA-1ML

    HCPCS Level II A9154: Artificial saliva, 1 ml

    HCPCS-A9155-ARTIFICIAL-SALIVA-30ML

    HCPCS Level II A9155: Artificial Saliva, 30 mL

    HCPCS-A9156-ORAL-MUCOADHESIVE-PER-1ML

    HCPCS Level II A9156: Oral Mucoadhesive, Per 1 ml

    HCPCS-A9180-PEDICULOSIS-TOPICAL-TREATMENT-PATIENT-ADMINISTRATION

    HCPCS Level II A9180: Pediculosis Topical Treatment for Patient/Caretaker

    HCPCS-A9268-PROGRAMMER-TRANSIENT-INGESTED-CAPSULE

    HCPCS Level II A9268: Programmer for Transient Orally Ingested Capsule

    HCPCS-A9269-PROGRAMMABLE-TRANSIENT-ORAL-CAPSULE

    HCPCS Level II A9269: Programmable Orally Ingested Capsule, Per Month

    HCPCS-A9270-NON-COVERED-ITEM-OR-SERVICE

    HCPCS A9270: Non-covered Item or Service

    Showing 1–10 of 138

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    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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